Results 21 to 30 of about 64,951 (237)
TRPV1 agonist, capsaicin, induces axon outgrowth after injury via Ca2+/PKA signaling [PDF]
, 2018 Preconditioning nerve injuries activate a pro-regenerative program that enhances axon regeneration for most classes of sensory neurons. However, nociceptive sensory neurons and central nervous system neurons regenerate poorly.
DiAntonio, Aaron +4 more
core +2 more sources
Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]
, 2017 Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core +1 more source
TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice [PDF]
, 2017 The capsaicin receptor TRPV1 has been widely characterized in the sensory system as a key component of pain and inflammation. A large amount of evidence shows that TRPV1 is also functional in the brain although its role is still debated.
Chiurchiù, Valerio +16 more
core +3 more sources
Stimulation of TRPV1 by green laser light [PDF]
, 2012 Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Gu, Quanbao +3 more
core +2 more sources
The Basal Thermal Sensitivity of the TRPV1 Ion Channel Is Determined by PKCβII [PDF]
, 2014 Copyright © 2014 the authors 0270-6474/14/348246-13$15.00/0.Peer reviewedPublisher ...
Hasan, Raquibul, Li, Lin, Zhang, Xuming
core +1 more source
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]
, 2007 The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
AlQatari, M +3 more
core +1 more source
Effects of Capsaicin on Adipogenic Differentiation in Bovine Bone Marrow Mesenchymal Stem Cell [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 Capsaicin is a major constituent of hot chili peppers that influences lipid metabolism in animals. In this study, we explored the effects of capsaicin on adipogenic differentiation of bovine bone marrow mesenchymal stem cells (BMSCs) in a dose- and time ...
Jin Young Jeong +8 more
doaj +1 more source
Frontiers in Chemistry, 2022 Silibinin and capsaicin both are natural product molecules with diverse biological activities. In this article, we investigated the anti-inflammatory effects of silibinin combined with capsaicin in lipopolysaccharide (LPS)-induced RAW264.7 cells.
Yingying Zheng +10 more
doaj +1 more source
Resilience to capsaicin-induced mitochondrial damage in trigeminal ganglion neurons
Molecular Pain, 2020 Capsaicin is an agonist of transient receptor potential cation channel subfamily V member 1 (TRPV1). Strong TRPV1 stimulation with capsaicin causes mitochondrial damage in primary sensory neurons.
Mamoru Shibata +7 more
doaj +1 more source
The Mysteries of Capsaicin-Sensitive Afferents
Frontiers in Physiology, 2020 A fundamental subdivision of nociceptive sensory neurons is named after their unique sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin-sensitive afferents.
Michael J. M. Fischer +2 more
doaj +1 more source