Results 11 to 20 of about 1,264,013 (289)
Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 Members of the TRP superfamily of ion channels mediate mechanosensation in some organisms, and have been suggested as candidates for the mechanotransduction channel in vertebrate hair cells.
Xudong Wu +8 more
doaj +2 more sources
Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna [PDF]
, 2011 [cat] Aquesta tesi es centra en la genètica de la migranya. La migranya comuna és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap.
Carreño, Oriel
core +6 more sources
TRP channels and analgesia [PDF]
Life Sciences, 2013 Since cloning and characterizing the first nociceptive ion channel Transient Receptor Potential (TRP) Vanilloid 1 (TRPV1), other TRP channels involved in nociception have been cloned and characterized, which include TRP Vanilloid 2 (TRPV2), TRP Vanilloid 3 (TRPV3), TRP Vanilloid 4 (TRPV4), TRP Ankyrin 1 (TRPA1) and TRP Melastatin 8 (TRPM8), more ...
Louis S, Premkumar, Mruvil, Abooj
openaire +2 more sources
Signal Transduction and Targeted Therapy, 2023 Transient receptor potential (TRP) channels are sensors for a variety of cellular and environmental signals. Mammals express a total of 28 different TRP channel proteins, which can be divided into seven subfamilies based on amino acid sequence homology ...
Miao Zhang +5 more
doaj +1 more source
TRP channels at a glance [PDF]
Journal of Cell Science, 2004 The t ransient r eceptor p otential (TRP) superfamily consists of a diverse set of proteins whose primary function is to regulate the plasma membrane permeability of animal cells to a variety of ions.
Raghu, Padinjat, Simon, Andrews
openaire +2 more sources
TRP channels in thermosensation
Current Opinion in Neurobiology, 2022 The ability to sense external temperature is assumed by somatosensory neurons, in which temperature information is converted to neural activity by afferent input to the central nervous system. Somatosensory neurons consist of various populations with specialized gene expression, including thermosensitive transient receptor potential ion channels ...
Makiko Kashio, Makoto Tominaga
openaire +2 more sources
Definition of two agonist types at the mammalian cold-activated channel TRPM8
eLife, 2016 Various TRP channels act as polymodal sensors of thermal and chemical stimuli, but the mechanisms whereby chemical ligands impact on TRP channel gating are poorly understood.
Annelies Janssens +8 more
doaj +1 more source
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]
, 2007 The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
Hjerling-Leffler, J +4 more
core +1 more source
Phosphorylation of the Drosophila transient receptor potential ion channel is regulated by the phototransduction cascade and involves several protein kinases and phosphatases. [PDF]
PLoS ONE, 2013 Protein phosphorylation plays a cardinal role in regulating cellular processes in eukaryotes. Phosphorylation of proteins is controlled by protein kinases and phosphatases.
Olaf Voolstra +4 more
doaj +1 more source
A novel ion channel formed by interaction of TRPML3 with TRPV5. [PDF]
, 2013 TRPML3 and TRPV5 are members of the mucolipin (TRPML) and TRPV subfamilies of transient receptor potential (TRP) cation channels. Based on sequence similarities of the pore forming regions and on structure-function evidence, we hypothesized that the pore
Becker, Lars +14 more
core +2 more sources