Results 1 to 10 of about 133,784 (309)

Transient Receptor Potential Channel Polymorphisms Are Associated with the Somatosensory Function in Neuropathic Pain Patients [PDF]

PLoS ONE, 2011
Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic ...
Frank Faltraco, Herta Flor, Sierk Haenisch   +2 more
exaly   +3 more sources

MAMMALIAN TRANSIENT RECEPTOR POTENTIAL TRPA1 CHANNELS: FROM STRUCTURE TO DISEASE [PDF]

, 2019
The transient receptor potential ankyrin (TRPA) channels are Ca2+-permeable nonselective cation channels remarkably conserved through the animal kingdom.
Boonen, Brett, Brett Boonen, Yeranddy A. Alpizar, Startek, Justyna B., Alvarez-Collazo, Julio, Alpizar, Yeranddy A., Julio Alvarez-Collazo, Talavera, Karel, Bernd Nilius, Naert, Robbe, Alicia Sanchez, Karel Talavera, Nilius, Bernd, AGUIAR ALPIZAR, Yeranddy, Robbe Naert, Alpizar, Yeranddy A, Justyna B. Startek, Startek, Justyna B, Sanchez, Alicia   +18 more
core   +2 more sources

Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel [PDF]

, 2011
This study investigated the role of urocortin (UCN), a member of the corticotrophin-releasing factor (CRF) family of peptides, in osteoclast maturation and function.
Hashethra Kumar, Charlotte E Combs, Locke, Ian C., Combs, C., Pirianov, G., Anthony P Albert, McCormick, James, Lawrence, K.M., Combs, Charlotte E., Locke, I.C., Fuller, K., Chambers, T.J., Albert, Anthony P., Ian C Locke, Fuller, Karen, Chambers, Timothy J., Grisha Pirianov, Albert, A.P., Pirianov, Grisha, Kumar, H., Karen Fuller, McCormick, J., Lawrence, Kevin M., James McCormick, Kumar, Hashethra, Timothy J Chambers, Kevin M Lawrence   +26 more
core   +2 more sources

Site-Specific Transient Receptor Potential Channel Mechanisms and Their Characteristics for Targeted Chronic Itch Treatment. [PDF]

Biomolecules
Go EJ, Lee JY, Kim YH, Park CK.
europepmc   +3 more sources

Anti-Inflammatory Effects of Serotonin Receptor and Transient Receptor Potential Channel Ligands in Human Small Intestinal Epithelial Cells [PDF]

Current Issues in Molecular Biology, 2023
Gregory Ian Robinson, Bo Wang, Marta Gerasymchuk   +2 more
exaly   +2 more sources

A Transient Receptor Potential Channel Expressed in Taste Receptor Cells

Nature Neuroscience, 2002
We used differential screening of cDNAs from individual taste receptor cells to identify candidate taste transduction elements in mice. Among the differentially expressed clones, one encoded Trpm5, a member of the mammalian family of transient receptor ...
Kozak, J. Ashot, J. Ashot Kozak, Cristian A. Pérez, Pérez, Cristian A., Minqing Rong, Hailin Zhang, Preuss, Axel K., Max, Marianna, Margolskee, Robert F., Rong, Minqing, Axel K. Preuss, Liquan Huang, Marianna Max, Robert F. Margolskee, Zhang, Hailin, Huang, Liquan   +15 more
core   +5 more sources

Transient Receptor Potential Channels and Itch

International Journal of Molecular Sciences, 2022
Transient Receptor Potential (TRP) channels are multifunctional sensory molecules that are abundant in the skin and are involved in the sensory pathways of itch, pain, and inflammation. In this review article, we explore the complex physiology of different TRP channels, their role in modulating itch sensation, and their contributions to the ...
Mahmoud, Omar, Soares, Georgia Biazus, Yosipovitch, Gil   +2 more
openaire   +2 more sources

Transient Receptor Potential (TRP) Channels [PDF]

, 2018
Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta, Taylor E T, Hughes, Vera Y, Moiseenkova-Bell   +2 more
openaire   +3 more sources

Transient Receptor Potential Cation Channels in Disease [PDF]

Physiological Reviews, 2007
The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd, Owsianik, Grzegorz, Voets, Thomas, Peters, John A.   +3 more
openaire   +2 more sources

The role of transient receptor potential channels in metastasis

Biomedicine & Pharmacotherapy, 2023
Metastasis is the hallmark of failed tumor treatment and is typically associated with death due to cancer. Transient receptor potential (TRP) channels affect changes in intracellular calcium concentrations and participate at every stage of metastasis.
Suwen, Bai, Yuan, Wei, Rong, Liu, Yuhua, Chen, Wanling, Ma, Minghua, Wang, Li, Chen, Yumei, Luo, Juan, Du   +8 more
openaire   +2 more sources