Results 21 to 30 of about 133,784 (309)

Drosophila TRPM channel is essential for the control of extracellular magnesium levels [PDF]

, 2010
The TRPM group of cation channels plays diverse roles ranging from sensory signaling to Mg2+ homeostasis. In most metazoan organisms the TRPM subfamily is comprised of multiple members, including eight in humans. However, the Drosophila TRPM subfamily is
Vladimir Chubanov, Craig Montell, Chen, Xiaodi, Xiaodi Chen, Anna S Dietz, Dietz, Anna S., Anna S. Dietz, Chubanov, Vladimir, Thomas Hofmann, Thomas Gudermann, Chen Xiaodi, Hofmann Thomas, Chubanov Vladimir, Dietz Anna S., Montell Craig, Gudermann, Thomas, Gudermann Thomas, Montell, Craig, Hofmann, Thomas   +18 more
core   +1 more source

Roles of transient receptor potential channels in pain [PDF]

Brain Research Reviews, 2009
Pain perception begins with the activation of primary sensory nociceptors. Over the past decade, flourishing research has revealed that members of the Transient Receptor Potential (TRP) ion channel family are fundamental molecules that detect noxious stimuli and transduce a diverse range of physical and chemical energy into action potentials in ...
Cheryl L, Stucky, Adrienne E, Dubin, Nathaniel A, Jeske, Sacha A, Malin, David D, McKemy, Gina M, Story   +5 more
openaire   +2 more sources

Transient Receptor Potential Channels and Metabolism.

Molecules and cells, 2019
Transient receptor potential (TRP) channels are nonselective cationic channels, conserved among flies to humans. Most TRP channels have well known functions in chemosensation, thermosensation, and mechanosensation. In addition to being sensing environmental changes, many TRP channels are also internal sensors that help maintain homeostasis.
Dhakal, Subash, Lee, Youngseok
openaire   +2 more sources

Canonical transient receptor potential channels in diabetes [PDF]

Experimental Biology and Medicine, 2012
Canonical transient receptor potential (TRPC) channel proteins have been identified as downstream molecules in a G protein-coupled receptor signaling pathway and are involved in a variety of cell functions due to their ability to regulate intracellular calcium signaling.
Sarabeth, Graham, Joseph P, Yuan, Rong, Ma   +2 more
openaire   +2 more sources

TRPM1 (transient receptor potential cation channel, subfamily M, member 1) [PDF]

, 2010
Review on TRPM1 (transient receptor potential cation channel, subfamily M, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Setaluri, V, S Devi, V Setaluri, Devi, S
core   +1 more source

The Transient Receptor Potential Superfamily of Ion Channels [PDF]

Journal of the American Society of Nephrology, 2004
ABSTRACT. The transient receptor potential (TRP) superfamily of proteins is cation-selective ion channels with six predicted transmembrane segments and intracellularly localized amino and carboxyl termini. Members of the TRP superfamily are identified on the basis of amino acid sequence and structural similarity and are classified into TRPC, TRPV, TRPM,
openaire   +2 more sources

Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes

, 2009
We investigate activation mechanisms of native TRPC1/C5/C6 channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and ...
Anthony P. Albert, Saleh, Sohag N., Albert, Anthony P., Sohag N. Saleh, William A. Large, Large, William A., Large, WA, Saleh, SN, Albert, AP   +8 more
core   +1 more source

Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel

, 2020
Increased generation of reactive oxygen species (ROS) and altered Ca2+ handling cause vascular damage in hypertension. Mechanisms linking these systems are unclear, but TRPM2 (transient receptor potential melastatin 2) could be important because TRPM2 is
Karla B. Neves, Aikaterini Anagnostopoulou, Rhian M. Touyz, Rhéure Alves-Lopes, Silvia Lacchini, Augusto C. Montezano, Francisco J. Rios   +6 more
core   +1 more source

TRPV1 (transient receptor potential cation channel, subfamily V, member 1) [PDF]

, 2010
Review on TRPV1 (transient receptor potential cation channel, subfamily V, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Santoni, G, Nabissi, M, NABISSI, MASSIMO, SANTONI, Giorgio   +3 more
core   +1 more source

TRPV6 (transient receptor potential cation channel, subfamily V, member 6) [PDF]

, 2010
Review on TRPV6 (transient receptor potential cation channel, subfamily V, member 6), with data on DNA, on the protein encoded, and where the gene is ...
Hediger, MA, Suzuki, Y, Y Suzuki, MA Hediger   +3 more
core   +1 more source