Results 41 to 50 of about 11,727,590 (290)
Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna [PDF]
, 2011 [cat] Aquesta tesi es centra en la genètica de la migranya. La migranya comuna és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap.
Carreño, Oriel
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Frontiers in Cardiovascular Medicine, 2022 Heart failure (HF) remains the leading cause of death, morbidity, and medical expenses worldwide. Treatments for HF with reduced ejection fraction have progressed in recent years; however, acute decompensated heart failure remains difficult to treat. The
Kun Ding +7 more
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Modulation of Transient Receptor Potential C Channel Activity by Cholesterol
Frontiers in Pharmacology, 2019 Changes of cholesterol level in the plasma membrane of cells have been shown to modulate ion channel function. The proposed mechanisms underlying these modulations include association of cholesterol to a single binding site at a single channel ...
Rita Gutorov +6 more
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Responses to transient receptor potential (TRP) channel agonists in Chlamydomonas reinhardtii
Biology Open, 2020 Pungent substances, such as capsaicin and gingerol, activate the transient receptor potential (TRP)-V1 channel and affect the feeding behaviors of animals.
Mamoru Wada +2 more
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Structural insights into TRPV2 activation by small molecules
Nature Communications, 2022 A non-selective calcium channel transient receptor potential vanilloid 2 (TRPV2) is a potential drug target. Here, the authors employ cryo-electron microscopy, in silico docking, and electrophysiology to identify a binding site for an activator 2 ...
Ruth A. Pumroy +11 more
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Roles of transient receptor potential channels in pain [PDF]
Brain Research Reviews, 2009 Pain perception begins with the activation of primary sensory nociceptors. Over the past decade, flourishing research has revealed that members of the Transient Receptor Potential (TRP) ion channel family are fundamental molecules that detect noxious stimuli and transduce a diverse range of physical and chemical energy into action potentials in ...
Cheryl L, Stucky +5 more
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Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]
, 2007 The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
Hjerling-Leffler, J +4 more
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Transient Receptor Potential Channels and Metabolism.
Molecules and cells, 2019 Transient receptor potential (TRP) channels are nonselective cationic channels, conserved among flies to humans. Most TRP channels have well known functions in chemosensation, thermosensation, and mechanosensation. In addition to being sensing environmental changes, many TRP channels are also internal sensors that help maintain homeostasis.
Dhakal, Subash, Lee, Youngseok
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Redox Regulation of Transient Receptor Potential Channels [PDF]
Antioxidants & Redox Signaling, 2014 Significance: Environmental and endogenous reactive species such as reactive oxygen species (ROS), reactive nitrogen species (RNS), and other electrophiles are not only known to exert toxic effects on organisms, but are also emerging as molecules that mediate cell ...
Kozai, Daisuke +2 more
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Drug Design, Development and Therapy, 2020 Jin Yu, Caifeng Zhu, Jiazhen Yin, Dongrong Yu, Feng Wan, Xuanli Tang, Xue Jiang Department of Nephrology, Guangxing Hospital Affiliated to ZheJiang Chinese Medical University (Key Laboratory of Zhejiang Province, Management of Kidney Disease), Hangzhou ...
Yu J +6 more
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