Results 51 to 60 of about 11,016,750 (197)
The Transient Receptor Potential Vanilloid 4 Channel and Cardiovascular Disease Risk Factors
Frontiers in Physiology, 2021 Vascular endothelial cells regulate arterial tone through the release of nitric oxide and other diffusible factors such as prostacyclin and endothelium derived hyperpolarizing factors.
Kenichi Goto, Takanari Kitazono
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TRPV1 (transient receptor potential cation channel, subfamily V, member 1) [PDF]
, 2010 Review on TRPV1 (transient receptor potential cation channel, subfamily V, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Santoni, G +3 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
TRPM1 (transient receptor potential cation channel, subfamily M, member 1) [PDF]
, 2010 Review on TRPM1 (transient receptor potential cation channel, subfamily M, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Setaluri, V, S Devi, V Setaluri, Devi, S
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
FEBS Open BioSensing environmental temperature is a complex process involving an array of channels expressed by nociceptive sensory neurons but is critical to allow animals to move away from suboptimal environments and find environments with ideal temperatures ...
Tadahiro Sawao +3 more
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Neural Regeneration ResearchInherited retinal degeneration refers to untreatable blinding diseases characterized by progressive photoreceptor loss. Photoreceptor degeneration is often associated with an excessive activation of poly(ADP-ribose) polymerase and Ca2+-dependent calpain ...
Jie Yan +9 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2021 Migraine is a common neurological disorder with few available treatment options. Recently, we have demonstrated the role of transient receptor potential cation channel subfamily C member 4 (TRPC4) in itch and the modulation of the calcitonin gene-related
Cinder Faith Cohen +5 more
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