Results 11 to 20 of about 11,727,590 (290)
Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator? [PDF]
Cells, 2014 In contrast to other Classical Transient Receptor Potential TRPC channels the function of TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain substantial functional signals over background in response to over-expression
Alexander Dietrich +2 more
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Transient Receptor Potential (TRP) Channels in Health and Disease
Cells, 2019 Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel, now named TRPC1, was cloned and published (reviewed in [...]
Alexander Dietrich
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A transient receptor potential channel expressed in taste receptor cells
Nature Neuroscience, 2002 We used differential screening of cDNAs from individual taste receptor cells to identify candidate taste transduction elements in mice. Among the differentially expressed clones, one encoded Trpm5, a member of the mammalian family of transient receptor potential (TRP) channels.
Pérez, Cristian A. +7 more
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Transient Receptor Potential Channels and Itch
International Journal of Molecular Sciences, 2022 Transient Receptor Potential (TRP) channels are multifunctional sensory molecules that are abundant in the skin and are involved in the sensory pathways of itch, pain, and inflammation. In this review article, we explore the complex physiology of different TRP channels, their role in modulating itch sensation, and their contributions to the ...
Mahmoud, Omar +2 more
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Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
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Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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Exploration of Targeted Anti-tumor Therapy, 2021 Cancer is an aging-associated disease and caused by genomic instability that is driven by the accumulation of mutations and epimutations in the aging process.
Wen-Li Hsu +3 more
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Thermo-sensitive TRP channels and prevention of major chronic diseases
Di-san junyi daxue xuebao, 2022 American scientists David Julius and Ardem Patapoutian won the Nobel Prize in physiology or medicine in 2021 for their groundbreaking discoveries of capsaicin receptor TRPV1 and menthol receptor TRPM8, revealing the secrets of temperature perception. The
ZHU Zhiming, LIU Daoyan
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Transient Receptor Potential Canonical Channels in Health and Disease: A 2020 Update [PDF]
, 2021 This 2020 Special Issue “TRPC channels” of Cells was dedicated to commemorating the 25th anniversary of discovery of the Transient Receptor Potential Canonical (TRPC) channel subfamily [...
Alexander G. Obukhov +7 more
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Frontiers in Physiology, 2022 Cardiac fibroblasts make up a major proportion of non-excitable cells in the heart and contribute to the cardiac structural integrity and maintenance of the extracellular matrix.
Asfree Gwanyanya +2 more
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