Porcine transient receptor potential channel 1 promotes adipogenesis and lipid deposition [PDF]
Journal of Lipid ResearchAdipose tissue, an important organ involved in energy metabolism and endocrine, is closely related to animal meat quality and human health. Transient receptor potential channel 1 (TRPC1), an ion transporter, is adipocytes’ major Ca2+ entry channel ...
Yu Fu +7 more
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Peripheral glutamate receptor and transient receptor potential channel mechanisms of craniofacial muscle pain [PDF]
Molecular Pain, 2020 Temporomandibular joint disorder is a common chronic craniofacial pain condition, often involving persistent, widespread craniofacial muscle pain.
Man-Kyo Chung, Jin Y Ro
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Transient Receptor Potential Channel Ankyrin 1: A Unique Regulator of Vascular Function [PDF]
Cells, 2021 TRPA1 (transient receptor potential ankyrin 1), the lone member of the mammalian ankyrin TRP subfamily, is a Ca2+-permeable, non-selective cation channel.
Michael G. Alvarado +2 more
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Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice [PDF]
Frontiers in Molecular Neuroscience, 2021 Migraine is a common neurological disorder with few available treatment options. Recently, we have demonstrated the role of transient receptor potential cation channel subfamily C member 4 (TRPC4) in itch and the modulation of the calcitonin gene-related
Cinder Faith Cohen +5 more
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The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature [PDF]
Frontiers in Immunology, 2017 Canonical or classical transient receptor potential channel 6 (TRPC6) is a Ca2+-permeable non-selective cation channel that is widely expressed in the heart, lung, and vascular tissues.
Monika Malczyk +8 more
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Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts [PDF]
Cardiology Journal, 2020 BACKGROUND: Cardiac fibroblasts (CFs) are principal extracellular matrix-producing cells. In response to injury, CFs transdifferentiate into myofibroblasts. Intracellular calcium (Ca2+) signaling, involved in fibroblast proliferation and differentiation,
Min-Soo Ahn +12 more
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Mouse transient receptor potential channel type 6 selectively regulates agonist-induced platelet function [PDF]
Biochemistry and Biophysics Reports, 2019 While changes in intracellular calcium levels is a central step in platelet activation and thrombus formation, the contribution and mechanism of receptor-operated calcium entry (ROCE) via transient receptor potential channels (TRPCs) in platelets remains
Enma V. Paez Espinosa +4 more
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A novel ion channel formed by interaction of TRPML3 with TRPV5. [PDF]
, 2013 TRPML3 and TRPV5 are members of the mucolipin (TRPML) and TRPV subfamilies of transient receptor potential (TRP) cation channels. Based on sequence similarities of the pore forming regions and on structure-function evidence, we hypothesized that the pore
Becker, Lars +4 more
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mSphere, 2023 Transient receptor potential (TRP) channels are evolutionarily conserved integral membrane proteins. They serve as crucial mediators of sensory signals and have profound effects on cellular functions.
Hongchen Wang +3 more
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Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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