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TRP Channels in Skin Biology and Pathophysiology
Pharmaceuticals, 2016 Ion channels of the Transient Receptor Potential (TRP) family mediate the influx of monovalent and/or divalent cations into cells in response to a host of chemical or physical stimuli. In the skin, TRP channels are expressed in many cell types, including
Michael J. Caterina, Zixuan Pang
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Post-Translational Modifications of TRP Channels
Cells, 2014 Transient receptor potential (TRP) channels constitute an ancient family of cation channels that have been found in many eukaryotic organisms from yeast to human.
Olaf Voolstra, Armin Huber
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TRP channels as potential targets for antischistosomals
International Journal for Parasitology: Drugs and Drug Resistance, 2018 Ion channels are membrane protein complexes that underlie electrical excitability in cells, allowing ions to diffuse through cell membranes in a regulated fashion. They are essential for normal functioning of the neuromusculature and other tissues.
Swarna Bais, Robert M. Greenberg
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Annual Review of Biochemistry, 2007 The TRP (Transient Receptor Potential) superfamily of cation channels is remarkable in that it displays greater diversity in activation mechanisms and selectivities than any other group of ion channels. The domain organizations of some TRP proteins are also unusual, as they consist of linked channel and enzyme domains.
Kartik, Venkatachalam, Craig, Montell
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TRP Channels in Digestive Tract Cancers. [PDF]
, 2020 Cancers of the digestive tract are among the most prevalent types of cancer. These types of cancers are often diagnosed at a late stage, which results in a poor prognosis.
Borgström, Anna +7 more
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TRP channels at a glance [PDF]
Journal of Cell Science, 2004 The t ransient r eceptor p otential (TRP) superfamily consists of a diverse set of proteins whose primary function is to regulate the plasma membrane permeability of animal cells to a variety of ions.
Raghu, Padinjat, Simon, Andrews
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TRP channels in thermosensation
Current Opinion in Neurobiology, 2022 The ability to sense external temperature is assumed by somatosensory neurons, in which temperature information is converted to neural activity by afferent input to the central nervous system. Somatosensory neurons consist of various populations with specialized gene expression, including thermosensitive transient receptor potential ion channels ...
Makiko Kashio, Makoto Tominaga
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Signal Transduction and Targeted Therapy, 2023 Transient receptor potential (TRP) channels are sensors for a variety of cellular and environmental signals. Mammals express a total of 28 different TRP channel proteins, which can be divided into seven subfamilies based on amino acid sequence homology ...
Miao Zhang +5 more
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The Role of Membrane Lipids in Light-Activation of Drosophila TRP Channels
Biomolecules, 2022 Transient Receptor Potential (TRP) channels constitute a large superfamily of polymodal channel proteins with diverse roles in many physiological and sensory systems that function both as ionotropic and metabotropic receptors.
Rita Gutorov +5 more
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Role of TRP channels in lymphatic function. [PDF]
Front PhysiolAccumulating evidence establishes intracellular Ca 2+ signaling as a central regulator of lymphatic endothelial function, with transient receptor potential (TRP) channels emerging as key ...
Cao X, Chen YL.
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