Transient Receptor Potential (TRP) Channels in Haematological Malignancies: An Update [PDF]
Biomolecules, 2021 Transient receptor potential (TRP) channels are improving their importance in different cancers, becoming suitable as promising candidates for precision medicine.
Federica Maggi +7 more
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Transient Receptor Potential (TRP) Channels in Health and Disease [PDF]
Cells, 2019 Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel, now named TRPC1, was cloned and published (reviewed in [...]
Alexander Dietrich
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Pharmaceuticals, 2018 Based on clinical and preclinical evidence, Transient Receptor Potential (TRP) channels have emerged as potential drug targets for the treatment of osteoarthritis, rheumatoid arthritis, and gout. This review summarizes the relevant data supporting a role
Tabitha Galindo, Jose Reyna, Andy Weyer
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Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts [PDF]
Pharmaceuticals, 2017 2017 marks the 20th anniversary of the molecular cloning by David Julius and colleagues (1997) of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1) [1].
Susan Huang, Arpad Szallasi
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Transient Receptor Potential (TRP) Channels in Pain, Neuropsychiatric Disorders, and Epilepsy [PDF]
International Journal of Molecular Sciences, 2023 Pharmacomodulation of membrane channels is an essential topic in the study of physiological conditions and disease status. Transient receptor potential (TRP) channels are one such family of nonselective cation channels that have an important influence ...
Som Singh +2 more
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Transient Receptor Potential (TRP) Channels: Markers and Therapeutic Targets for Cancer? [PDF]
Biomolecules, 2022 This Special Issue in Biomolecules explores the roles of Transient Receptor Potential channels (TRPs) in cancer [...]
Maria Beatrice Morelli +1 more
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Functional Importance of Transient Receptor Potential (TRP) Channels in Neurological Disorders [PDF]
Frontiers in Cell and Developmental Biology, 2021 Transient receptor potential (TRP) channels are transmembrane protein complexes that play important roles in the physiology and pathophysiology of both the central nervous system (CNS) and the peripheral nerve system (PNS).
Kihwan Lee +5 more
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Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers. [PDF]
PLoS Neglected Tropical Diseases, 2018 The anthelmintic praziquantel (±PZQ) serves as a highly effective antischistosomal therapy. ±PZQ causes a rapid paralysis of adult schistosome worms and deleterious effects on the worm tegument.
Gihan S Gunaratne +3 more
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Signal Transduction and Targeted Therapy, 2023 Transient receptor potential (TRP) channels are sensors for a variety of cellular and environmental signals. Mammals express a total of 28 different TRP channel proteins, which can be divided into seven subfamilies based on amino acid sequence homology ...
Miao Zhang +5 more
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Pathophysiological Roles of Transient Receptor Potential (Trp) Channels and Zinc Toxicity in Brain Disease [PDF]
International Journal of Molecular Sciences, 2023 Sang Won Suh, Bo Young Choi, A Ra Kho
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