Results 31 to 40 of about 19,126 (203)
Acta Pharmaceutica Sinica B, 2022 Transient receptor potential (TRP) channels are one primary type of calcium (Ca2+) permeable channels, and those relevant transmembrane and intracellular TRP channels were previously thought to be mainly associated with the regulation of cardiovascular ...
Tiecheng Zhong +7 more
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A polycycstin-type transient receptor potential (Trp) channel that is activated by ATP [PDF]
Biology Open, 2016 ATP and ADP are ancient extra-cellular signalling molecules that in Dictyostelium amoebae cause rapid, transient increases in cytosolic calcium due to an influx through the plasma membrane. This response is independent of hetero-trimeric G-proteins, the putative IP3 receptor IplA and all P2X channels.
David Traynor, Robert R. Kay
openaire +3 more sources
Pharmaceuticals, 2018 Based on clinical and preclinical evidence, Transient Receptor Potential (TRP) channels have emerged as potential drug targets for the treatment of osteoarthritis, rheumatoid arthritis, and gout. This review summarizes the relevant data supporting a role
Tabitha Galindo, Jose Reyna, Andy Weyer
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Transient Receptor Potential Channels and Inflammatory Bowel Disease
Frontiers in Immunology, 2020 The transient receptor potential (TRP) cation channels are present in abundance across the gastrointestinal (GI) tract, serving as detectors for a variety of stimuli and secondary transducers for G-protein coupled receptors.
Yiding Chen +8 more
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Frontiers in Cellular Neuroscience, 2023 BackgroundTransient receptor potential (TRP) channels have been found to have significant implications in neuronal outgrowth, survival, inflammatory neurogenic pain, and various epileptogenic processes.
Ishak Suat Ovey +7 more
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TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
Cells, 2021 The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate array of stimuli, interacts with a multitude of proteins, and is modulated
Trine L. Toft-Bertelsen, Nanna MacAulay
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Potential role of transient receptor potential (TRP) channels in bladder cancer cells. [PDF]
J Physiol Sci, 2014 Transient receptor potential (TRP) channels play important roles in thermal, chemical, and mechanical sensation in various tissues. In this study, we investigated the differences in urothelial TRP channels between normal urothelial cells and bladder cancer cells.
Mizuno H +7 more
europepmc +3 more sources
Purification of Functional Human TRP Channels Recombinantly Produced in Yeast
Cells, 2019 (1) Background: Human transient receptor potential (TRP) channels constitute a large family of ion-conducting membrane proteins that allow the sensation of environmental cues.
Liying Zhang +7 more
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Function of TRP channels in monocytes/macrophages
Frontiers in Immunology, 2023 The transient receptor potential channel (TRP channel) family is a kind of non- specific cation channel widely distributed in various tissues and organs of the human body, including the respiratory system, cardiovascular system, immune system, etc.
Jiangbo Wu +33 more
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Arquivos de Neuro-Psiquiatria, 2022 Background Pain is an uncomfortable sensation in the body. Kaempferol is a flavonoid with antinociceptive effects. Transient receptor potential (TRP) channels have been characterized in the sensory system.
Mohammad Mahdi Zarei +2 more
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