Results 11 to 20 of about 19,126 (203)
Transient receptor potential (TRP) channels in the airway: role in airway disease [PDF]
British Journal of Pharmacology, 2014 Over the last few decades, there has been an explosion of scientific publications reporting the many and varied roles of transient receptor potential (TRP) ion channels in physiological and pathological systems throughout the body. The aim of this review is to summarize the existing literature on the role of TRP channels in the lungs and discuss what ...
Eric Dubuis
exaly +7 more sources
Transient receptor potential (TRP) gene superfamily encoding cation channels [PDF]
Human Genomics, 2011 Transient receptor potential (TRP) non-selective cation channels constitute a superfamily, which contains 28 different genes. In mammals, this superfamily is divided into six subfamilies based on differences in amino acid sequence homology between the ...
Pan Zan, Yang Hua, Reinach Peter S
doaj +3 more sources
Editorial: Transient receptor potential channels (TRP): signal transduction
Frontiers in Molecular Biosciences, 2023 Alexander Dietrich +3 more
doaj +3 more sources
Transient Receptor Potential (TRP) Channels in Tumor Vascularization. [PDF]
Int J Mol Sci, 2022 Tumor diseases are unfortunately quick spreading, even though numerous studies are under way to improve early diagnosis and targeted treatments that take into account both the different characteristics associated with the various tumor types and the conditions of individual patients.
Perna A +8 more
europepmc +6 more sources
Transient Receptor Potential (TRP) Channels. [PDF]
Subcell Biochem, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Samanta A +2 more
europepmc +5 more sources
Transient Receptor Potential (TRP) Channels in Airway Toxicity and Disease: An Update. [PDF]
Cells, 2022 Our respiratory system is exposed to toxicants and pathogens from both sides: the airways and the vasculature. While tracheal, bronchial and alveolar epithelial cells form a natural barrier in the airways, endothelial cells protect the lung from perfused toxic compounds, particulate matter and invading microorganism in the vascular system.
Müller I +5 more
europepmc +4 more sources
Transient Receptor Potential (TRP) channels in T cells. [PDF]
Semin Immunopathol, 2016 The transient receptor potential (TRP) family of ion channels is widely expressed in many cell types and plays various physiological roles. Growing evidence suggests that certain TRP channels are functionally expressed in the immune system. Indeed, an increasing number of reports have demonstrated the functional expression of several TRP channels in ...
Bertin S, Raz E.
europepmc +4 more sources
Role of Known Transient Receptor Potential Vanilloid Channels in Modulating Cardiac Mechanobiology
Frontiers in Physiology, 2021 The transient receptor potential (TRP) channels have been described in almost every mammalian cell type. Several members of the Vanilloid (TRPV) subtype have been found to play important roles in modulating cardiac structure and function through Ca2 ...
Michael Miller +6 more
doaj +1 more source
Transient receptor potential (TRP) channels and cardiac fibrosis. [PDF]
Curr Top Med Chem, 2013 Cardiac fibrosis is associated with most cardiac diseases. Fibrosis is an accumulation of excessive extracellular matrix proteins (ECM) synthesized by cardiac fibroblasts and myofibroblasts. Fibroblasts are the most prevalent cell type in the heart, comprising 75% of cardiac cells.
Yue Z, Zhang Y, Xie J, Jiang J, Yue L.
europepmc +4 more sources
Materials Today Advances, 2023 Reactive oxygen species (ROS) play an important role in regulating various physiological functions by activating specific ion channels to mediate cell growth, proliferation, regeneration, and apoptosis.
Boying Li +7 more
doaj +1 more source