Results 31 to 40 of about 32,080 (252)
The role of transient receptor potential channels in joint diseases [PDF]
European Cells & Materials, 2017 ransient receptor potential channels (TRP channels) are cation selective transmembrane receptors with diverse structures, activation mechanisms and physiological functions.
O Krupkova, J Zvick, K Wuertz-Kozak
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Sequence and structural conservation reveal fingerprint residues in TRP channels
eLife, 2022 Transient receptor potential (TRP) proteins are a large family of cation-selective channels, surpassed in variety only by voltage-gated potassium channels.
Deny Cabezas-Bratesco +7 more
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Sensing with TRP channels [PDF]
Nature Chemical Biology, 2005 Drosophila melanogaster flies carrying the trp (transient receptor potential) mutation are rapidly blinded by bright light, because of the absence of a Ca2+-permeable ion channel in their photoreceptors. The identification of the trp gene and the search for homologs in yeast, flies, worms, zebrafish and mammals has led to the discovery of a large ...
Voets, Thomas +3 more
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Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels.
PLoS ONE, 2023 Transient receptor potential (TRP) channels are activated by various extracellular and intracellular stimuli and are involved in many physiological events.
Manae Tatsumi +8 more
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Purification of Functional Human TRP Channels Recombinantly Produced in Yeast
Cells, 2019 (1) Background: Human transient receptor potential (TRP) channels constitute a large family of ion-conducting membrane proteins that allow the sensation of environmental cues.
Liying Zhang +7 more
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Cannabinoid Ligands Targeting TRP Channels
Frontiers in Molecular Neuroscience, 2019 Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of chemical and physical stimuli.
Chanté Muller +2 more
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Frontiers in Cell and Developmental Biology, 2021 Malignant glioma including glioblastoma (GBM) is the most common group of primary brain tumors. Despite standard optimized treatment consisting of extensive resection followed by radiotherapy/concomitant and adjuvant therapy, GBM remains one of the most ...
Giorgia Chinigò +7 more
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Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 The transient receptor potential (TRP) channels are a large family of proteins with six main subfamilies termed the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and TRPA (ankyrin) groups. The sheer number of different TRPs with distinct functions supports the statement that these channels are involved in ...
S E, Jordt, B E, Ehrlich
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Cells, 2018 Chemicals can exhibit significant toxic properties. While for most compounds, unspecific cell damaging processes are assumed, a plethora of chemicals exhibit characteristic odors, suggesting a more specific interaction with the human body.
Dirk Steinritz +4 more
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