Results 31 to 40 of about 886,471 (280)
Annual Review of Biochemistry, 2007 The TRP (Transient Receptor Potential) superfamily of cation channels is remarkable in that it displays greater diversity in activation mechanisms and selectivities than any other group of ion channels. The domain organizations of some TRP proteins are also unusual, as they consist of linked channel and enzyme domains.
Kartik, Venkatachalam, Craig, Montell
openaire +3 more sources
Current Research in Physiology, 2021 Members of the transient receptor potential (TRP) channels that are expressed in the kidney have gained prominence in recent years following discoveries of their role in maintaining the integrity of the filtration barrier, regulating tubular reabsorption
Praghalathan Kanthakumar +1 more
doaj +1 more source
Targeting TRP channels: recent advances in structure, ligand binding, and molecular mechanisms [PDF]
Frontiers in Molecular Neuroscience, 2023 Transient receptor potential (TRP) channels are a large and diverse family of transmembrane ion channels that are widely expressed, have important physiological roles, and are associated with many human diseases.
Jian Huang +3 more
doaj +2 more sources
Frontiers in Immunology, 2023 Transient receptor potential (TRP) channels are a class of transmembrane proteins that can sense a variety of physical/chemical stimuli, participate in the pathological processes of various diseases and have attracted increasing attention from ...
Yuping Zheng +7 more
doaj +1 more source
Neuroscience Insights, 2023 The transient receptor potential (TRP) superfamily of ion channels in humans comprises voltage-gated, non-selective cation channels expressed both in excitable as well as non-excitable cells. Four TRP channel subunits associate to create functional homo-
Santosh Anand, Senthilkumar Rajagopal
doaj +1 more source
TRP Channels in Digestive Tract Cancers. [PDF]
, 2020 Cancers of the digestive tract are among the most prevalent types of cancer. These types of cancers are often diagnosed at a late stage, which results in a poor prognosis.
Borgström, Anna +11 more
core +2 more sources
TRP channels at a glance [PDF]
Journal of Cell Science, 2004 The t ransient r eceptor p otential (TRP) superfamily consists of a diverse set of proteins whose primary function is to regulate the plasma membrane permeability of animal cells to a variety of ions.
Raghu, Padinjat, Simon, Andrews
openaire +2 more sources
Signal Transduction and Targeted Therapy, 2023 Transient receptor potential (TRP) channels are sensors for a variety of cellular and environmental signals. Mammals express a total of 28 different TRP channel proteins, which can be divided into seven subfamilies based on amino acid sequence homology ...
Miao Zhang +5 more
doaj +1 more source
TRP channels: Role in neurodegenerative diseases and therapeutic targets
Heliyon, 2023 TRP (Transient receptor potential) channels are integral membrane proteins consisting of a superfamily of cation channels that allow permeability of both monovalent and divalent cations. TRP channels are subdivided into six subfamilies: TRPC, TRPV, TRPM,
Mashoque Ahmad Rather +6 more
doaj +1 more source
TRP channels in thermosensation
Current Opinion in Neurobiology, 2022 The ability to sense external temperature is assumed by somatosensory neurons, in which temperature information is converted to neural activity by afferent input to the central nervous system. Somatosensory neurons consist of various populations with specialized gene expression, including thermosensitive transient receptor potential ion channels ...
Makiko Kashio, Makoto Tominaga
openaire +2 more sources