Results 51 to 60 of about 852,547 (280)
Frontiers in Cell and Developmental Biology, 2021 Malignant glioma including glioblastoma (GBM) is the most common group of primary brain tumors. Despite standard optimized treatment consisting of extensive resection followed by radiotherapy/concomitant and adjuvant therapy, GBM remains one of the most ...
Giorgia Chinigò +7 more
doaj +1 more source
Purification of Functional Human TRP Channels Recombinantly Produced in Yeast
Cells, 2019 (1) Background: Human transient receptor potential (TRP) channels constitute a large family of ion-conducting membrane proteins that allow the sensation of environmental cues.
Liying Zhang +7 more
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TRP channels as biological sensors [PDF]
, 2008 TRP is the most recently discovered family of ion channels and display the largest structure and function diversity among ion channels. Most TRP channels are key elements in sensory cells, where they are involved in the response to a broad range of ...
Astorga, Guadalupe, Bacigalupo, Juan
core
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
X-ray crystallography of TRP channels
Channels, 2018 Transient receptor potential (TRP) ion channels are molecular sensors of a large variety of stimuli including temperature, mechanical stress, voltage, small molecules including capsaicin and menthol, and lipids such as phosphatidylinositol 4,5 ...
Appu K. Singh +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy
, 2018 Cellular transport of ions, especially by ion channels, regulates physiological function. The transient receptor potential (TRP) channels, with 30 identified so far, are cation channels with high calcium permeability.
Bishnoi, M. +15 more
core +1 more source
The pharmacology of
British Journal of Pharmacology, 2014 This themed issue of the British Journal of Pharmacology contains review and research articles on recent advances in transient receptor potential (TRP) channel pharmacology. The review articles, written by a panel of distinguished experts, address the rapid progress in TRP channel research in fields as diverse as oncology, urology, dermatology ...
Peter, Holzer, Angelo A, Izzo
openaire +3 more sources
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
Advanced Healthcare Materials, EarlyView.The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source
Cells, 2018 Chemicals can exhibit significant toxic properties. While for most compounds, unspecific cell damaging processes are assumed, a plethora of chemicals exhibit characteristic odors, suggesting a more specific interaction with the human body.
Dirk Steinritz +4 more
doaj +1 more source