Results 51 to 60 of about 886,471 (280)
Frontiers in Cell and Developmental Biology, 2021 Malignant glioma including glioblastoma (GBM) is the most common group of primary brain tumors. Despite standard optimized treatment consisting of extensive resection followed by radiotherapy/concomitant and adjuvant therapy, GBM remains one of the most ...
Giorgia Chinigò +7 more
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 The progression of cells from a normal differentiated state in which rates of proliferation and apoptosis are balanced to a tumorigenic and metastatic state involves the accumulation of mutations in multiple key signalling proteins and the evolution and clonal selection of more aggressive cell phenotypes. These events are associated with changes in the
Prevarskaya, Natalia +2 more
openaire +4 more sources
Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels.
PLoS ONE, 2023 Transient receptor potential (TRP) channels are activated by various extracellular and intracellular stimuli and are involved in many physiological events.
Manae Tatsumi +8 more
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Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
TRP channels as biological sensors [PDF]
, 2008 TRP is the most recently discovered family of ion channels and display the largest structure and function diversity among ion channels. Most TRP channels are key elements in sensory cells, where they are involved in the response to a broad range of ...
Astorga, Guadalupe, Bacigalupo, Juan
core
Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy
, 2018 Cellular transport of ions, especially by ion channels, regulates physiological function. The transient receptor potential (TRP) channels, with 30 identified so far, are cation channels with high calcium permeability.
Bishnoi, M. +15 more
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Cells, 2018 Chemicals can exhibit significant toxic properties. While for most compounds, unspecific cell damaging processes are assumed, a plethora of chemicals exhibit characteristic odors, suggesting a more specific interaction with the human body.
Dirk Steinritz +4 more
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Advanced Science, EarlyView.ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
TRP Channels and Pruritus [PDF]
, 2013 Itch (pruritus) is one of the most often seen sensory phenomena in clinical practice. Recent neurophysiological findings proposed the existence of a novel pruriceptive system which includes a multitude of pruritogenic (itch-inducing) peripheral mediators,
Tóth, Balázs István +2 more
core +1 more source
X-ray crystallography of TRP channels
Channels, 2018 Transient receptor potential (TRP) ion channels are molecular sensors of a large variety of stimuli including temperature, mechanical stress, voltage, small molecules including capsaicin and menthol, and lipids such as phosphatidylinositol 4,5 ...
Appu K. Singh +3 more
doaj +1 more source