Results 31 to 40 of about 963,526 (173)

Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]

, 2013
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Howell, Matthew, Hacker, Christian, Lucocq, John Milton, Lucocq, John, Bhella, David   +4 more
core   +1 more source

ATP-Bound State of the Uncoupling Protein 1 (UCP1) from Molecular Simulations

, 2023
The uncoupling protein 1 (UCP1) dissipates the transmembrane (TM) proton gradient in the inner mitochondrial membrane (IMM) by leaking protons across the membrane and producing heat in the process.
Luise Jacobsen (10179291), Laura Lydersen (17333604), Himanshu Khandelia (241326)   +2 more
core   +2 more sources

Essential mitochondrial activity in Physcomitrium patens relies on complementary cytochrome and alternative oxidase pathways

The Plant Journal, Volume 127, Issue 5, September 2026.
SUMMARY Mitochondrial respiration catalyses the transfer of electrons from NADH to oxygen through the activity of five multiprotein complexes. In plants, mitochondria also possess additional alternative electron transport pathways, including the alternative oxidase (AOX) pathway, which transfers electrons from ubiquinol to O2, bypassing the cytochrome ...
Shun‐Ling Tan, Antoni M. Vera‐Vives, Heyu Wang, Xing Huang, Claudia Beraldo, Alessandro Alboresi, Tomas Morosinotto   +6 more
wiley   +1 more source

Simulated Microgravity Reprograms Host Cell Architecture and Mitochondrial Function, Altering Toxoplasma gondii Growth

FASEB BioAdvances, Volume 8, Issue 7, July 2026.
Simulated microgravity (SMG) induces host‐cell‐specific mitochondrial remodeling that differentially regulates T. gondii intracellular growth. Mitochondrial dysfunction with reduced ATP production is associated with impaired parasite invasion and growth in HFF, whereas mitochondrial adaptation with increased ATP production in Vero cells is associated ...
Musfika Tasnim Shirin, Takafumi Yamada, Daisuke Kondoh, Hiroki Bochimoto, Kentaro Kato   +4 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, Volume 4, Issue 2, June 2026.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats

The Journal of Physiology, Volume 604, Issue 12, Page 4678-4706, 15 June 2026.
Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe, Audrys Pauza, Olivia M. S. Gold, Xin Shen, Fernanda Brognara, Rosanna Roberts Nonu, Dylan K. Pen, Aabharika Bose, Emma N. Bardsley, Anna P. Ponnampalam, Davi J. A. Moraes, Julian F. R. Paton   +11 more
wiley   +1 more source

Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]

, 2005
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Spyer, K. Michael, Llaudet, E, Gourine, Alexander V., Spyer, KM, Dale, Nicholas, Llaudet, Enrique, Dale, N, Gourine, AV   +7 more
core   +1 more source

HIF‐Regulated Pannexin‐1 Channel Drives Luminal ATP Accumulation in Kidney Cysts

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Autosomal dominant polycystic kidney disease causes progressive cyst enlargement in the kidneys, leading to hypoxia and induction of HIF‐1α. Our study identifies HIF‐1α‐dependent transcriptional upregulation of Pannexin1 (PANX1) in the apical membrane of cyst epithelial cells, promoting ATP release into the cyst lumen.
Kathrin Skoczynski, Julia Katharina Scholz, Raluca Ursu, Johannes Schödel, Steffen Grampp, Stephanie Naas, Victoria Lauer, Mario Schiffer, Maike Büttner‐Herold, Bjoern Buchholz, Andre Kraus   +10 more
wiley   +1 more source

Aggregation of Phosphates Enhances Enzyme Activity in Aqueous Solution

ChemPhysChem, Volume 27, Issue 9, 14 May 2026.
At high millimolar concentrations, adenosine triphosphate aggregates in aqueous solution. This can increase the catalytic activity of enzymes such as cytochrome c, horse radish peroxidase, and laccase. Diffusion coefficients and viscosities of tetrabutylammonium dihydrogen phosphate ([NBu4]+[H2PO4]−), potassium dihydrogen phosphate (K+[H2PO4 ...
Sourav Bajpayee, Velsuba Murugan, William S. Price, Subinoy Rana, Jonathon E. Beves   +4 more
wiley   +1 more source

Ontogeny of purinergic receptor-regulated Ca2+ signaling in mouse cortical collecting duct epithelium [PDF]

, 2002
Changes in ATP-induced increase in {[}Ca2+], during collecting duct ontogeny were studied in primary monolayer cultures of mouse ureteric bud (UB) and cortical collecting duct (CCD) cells by Fura-PE3 fluorescence ratio imaging.
Tschop, J., Borscheid, R., Huber, S. M., Braun, G. S., Horster, M. F.   +4 more
core   +1 more source