Results 1 to 10 of about 13,400,035 (354)
Estrogenic control of mitochondrial function
Redox Biology, 2020 Sex-based differences in human disease are caused in part by the levels of endogenous sex steroid hormones which regulate mitochondrial metabolism. This review updates a previous review on how estrogens regulate metabolism and mitochondrial function that
Carolyn M. Klinge
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Mitochondrial calcium shapes B cell signaling and mitochondrial function [PDF]
Frontiers in ImmunologyIntroductionCalcium (Ca2+) signaling plays a pivotal role in determining B cell fate, shaping processes such as activation, differentiation, anergy or apoptosis.
Hakan Taskiran +15 more
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European Psychiatry, 2023 Introduction Current evidence has hypothesized the involvement of mitochondrial dysfunction during the acute episodes of BD compared to symptomatic remission.
A. Giménez-Palomo +12 more
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Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response. [PDF]
, 2010 The pro-apoptotic function of p53 has been well defined in preventing genomic instability and cell transformation. However, the intriguing fact that p53 contributes to a pro-survival advantage of tumor cells under DNA damage conditions raises a critical ...
Duru, Nadire +5 more
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Antioxidants, 2022 Intrauterine growth restriction (IUGR) affects 5–10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al.
Glòria Garrabou +11 more
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The Key Role of Mitochondrial Function in Health and Disease
Antioxidants, 2023 The role of mitochondrial function in health and disease has become increasingly recognized, particularly in the last two decades. Mitochondrial dysfunction as well as disruptions of cellular bioenergetics have been shown to be ubiquitous in some of the ...
Iñigo San-Millán
semanticscholar +1 more source
Role of Copper on Mitochondrial Function and Metabolism
Frontiers in Molecular Biosciences, 2021 Copper is essential for life processes like energy metabolism, reactive oxygen species detoxification, iron uptake, and signaling in eukaryotic organisms.
L. Ruíz +2 more
semanticscholar +1 more source
Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond.
Free Radical Biology & Medicine, 2022 Mitochondria are unique and essential organelles that mediate many vital cellular processes including energy metabolism and cell death. The transcription factor Nrf2 (NF-E2 p45-related factor 2) has emerged in the last few years as an important modulator
Noemí Esteras, A. Abramov
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Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells
bioRxiv, 2021 We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and to neurons in mice ...
A. D'Souza +15 more
semanticscholar +1 more source
Mammalian AKT, the Emerging Roles on Mitochondrial Function in Diseases
Aging and Disease, 2022 Mitochondrial dysfunction may play a crucial role in various diseases due to its roles in the regulation of energy production and cellular metabolism. Serine/threonine kinase (AKT) is a highly recognized antioxidant, immunomodulatory, anti-proliferation,
Xiaoxian Xie +4 more
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