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PLANT UNCOUPLING MITOCHONDRIAL PROTEINS
Annual Review of Plant Biology, 2006Uncoupling proteins (UCPs) are membrane proteins that mediate purine nucleotide-sensitive free fatty acid-activated H+ flux through the inner mitochondrial membrane. After the discovery of UCP in higher plants in 1995, it was acknowledged that these proteins are widely distributed in eukaryotic organisms.
Eugenio Vercesi, Anibal +5 more
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Mechanisms of mitochondrial protein import
Essays in Biochemistry, 2000Mitochondria import most of their proteins from the cytosol. Precursor forms of most matrix proteins as well as some IM and IMS proteins are synthesized on cytoplasmic ribosomes with N-terminal cleavable signal sequences. Many other mitochondrial proteins including IM carrier proteins contain internal targeting sequences.
D M, Gordon, A, Dancis, D, Pain
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Mitochondrial transport proteins of the brain
Journal of Neuroscience Research, 2007Abstract In this study, cellular distribution and activity of glutamate and γ‐aminobutyric acid (GABA) transport as well as oxoglutarate transport across brain mitochondrial membranes were investigated.
D A, Berkich +5 more
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Supernumerary proteins of mitochondrial ribosomes
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014Messenger RNAs encoded by mitochondrial genomes are translated on mitochondrial ribosomes that have unique structure and protein composition compared to prokaryotic and cytoplasmic ribosomes. Mitochondrial ribosomes are a patchwork of core proteins that share homology with prokaryotic ribosomal proteins and new, supernumerary proteins that can be ...
Oliver, Rackham, Aleksandra, Filipovska
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The Mitochondrial Protein Import Motor
Biological Chemistry, 2000Mitochondrial proteins are synthesized as precursor proteins in the cytosol and are posttranslationally imported into the organelle. A complex system of translocation machineries recognizes and transports the precursor polypeptide across the mitochondrial membranes.
Strub, Andreas +3 more
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Proteomic Analysis of Mitochondrial Proteins
2004Publisher Summary The chapter discusses the proteomic analysis of mitochondrial proteins. Mitochondria play a central role in multiple cellular processes. In addition, mitochondrial dysfunction has been implicated in the cause of numerous diseases and disorders, including defects in energy metabolism, alzheimer's and parkinson's diseases, cancer ...
Mary F, Lopez +7 more
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Solubilization of mitochondrial proteins
Biochimica et Biophysica Acta (BBA) - General Subjects, 1964R K, BURKHARD, G, KROPF
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Mining the mitochondrial proteome
Nature Reviews Molecular Cell Biology, 2022Paulina Strzyz, Strzyz Paulina
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Mechanisms of BCL-2 family proteins in mitochondrial apoptosis
Nature Reviews Molecular Cell Biology, 2023Peter E Czabotar +2 more
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