Results 41 to 50 of about 2,483,935 (295)

Mitochondrial protein import [PDF]

, 1988
Transport of nuclear-encoded precursor proteins into mitochondria includes proteolytic cleavage of aminoterminal targeting sequences in the mitochondrial matrix. We have isolated the processing activity from Neurospora crassa.
Hawlitschek, Gerhard, Schneider, Helmut, Tropschug, Maximilian, Hartl, Franz-Ulrich, Neupert, Walter, Schmidt, Bernd   +5 more
core   +1 more source

Mechanisms of Modulation of Mitochondrial Architecture

Biomolecules, 2023
Mitochondrial network architecture plays a critical role in cellular physiology. Indeed, alterations in the shape of mitochondria upon exposure to cellular stress can cause the dysfunction of these organelles.
Juan Pablo Muñoz, Fernanda Luisa Basei, María Laura Rojas, David Galvis, Antonio Zorzano   +4 more
doaj   +1 more source

Transport of proteins into mitochondria [PDF]

, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core   +1 more source

Targeting and Insertion of Membrane Proteins in Mitochondria

Frontiers in Cell and Developmental Biology, 2021
Mitochondrial membrane proteins play an essential role in all major mitochondrial functions. The respiratory complexes of the inner membrane are key for the generation of energy. The carrier proteins for the influx/efflux of essential metabolites to/from
Ross Eaglesfield, Kostas Tokatlidis
doaj   +1 more source

Early steps in mitochondrial protein import [PDF]

, 1990
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Stuart, Rosemary A., Neupert, Walter, Nicholson, Donald W.   +2 more
core   +1 more source

Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide

Frontiers in Medicine, 2018
The biological roles of heme and nonheme nitrosyl complexes in physiological and pathophysiological conditions as metabolic key players are considered in this study. Two main physiological functions of protein nitrosyl complexes are discussed—(1) a depot
Anatoly N. Osipov, Tatiana V. Machneva, Evgeny A. Buravlev, Evgeny A. Buravlev, Yury A. Vladimirov, Yury A. Vladimirov   +5 more
doaj   +1 more source

Generation of a mitochondrial protein compendium in Dictyostelium discoideum

iScience, 2022
Summary: The social ameba Dictyostelium discoideum has emerged as a powerful model to study mitochondrial genetics and bioenergetics. However, a comprehensive inventory of mitochondrial proteins that is critical to understanding mitochondrial processes ...
Anna V. Freitas, Jake T. Herb, Miao Pan, Yong Chen, Marjan Gucek, Tian Jin, Hong Xu   +6 more
doaj   +1 more source

Mitochondrial Protein Import [PDF]

, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Pfanner, Nikolaus, Tropschug, Maximilian, Neupert, Walter   +2 more
core   +1 more source

Biochemical and Proteomic Analyses in Drought-Tolerant Wheat Mutants Obtained by Gamma Irradiation

Plants
The bread wheat cultivar (Triticum aestivum L. cv. Sagittario) as a parental line and its mutant, drought-tolerant lines (Mutant lines 4 and 5) were subjected to polyethylene glycol (PEG)-induced drought.
Ayşe Şen, Tamer Gümüş, Aslıhan Temel, İrfan Öztürk, Özge Çelik   +4 more
doaj   +1 more source

A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria [PDF]

, 1994
The novel genetic method of "sheltered RIP" (repeat induced point mutation) was used to generate a Neurospora crassa mutant in which MOM19, a component of the protein import machinery of the mitochondrial outer membrane, can be depleted.
W Neupert, Lill, Roland, Harkness, Troy A.A.,, van der Klei, Ida, Neupert, Walter, Harkness, Troy A. A., Klei, Ida J. van der, TA Harkness, Klei, Ida van der,, Nargang, Frank E.,, I van der Klei, Neupert, Walter,, Lill, Roland,, van der Klei, Ida ; id_orcid, Nargang, Frank E., FE Nargang, R Lill   +16 more
core   +3 more sources