Results 21 to 30 of about 600,085 (261)
ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway
Life Science Alliance, 2021 The GET pathway is required to target non-imported mitochondrial carrier proteins to the endoplasmic reticulum, which prevents their deposition into Hsp42-dependent protein foci.
Tianyao Xiao +2 more
doaj +1 more source
THE MITOCHONDRIAL PROTEIN IMPORT APPARATUS [PDF]
Annual Review of Biochemistry, 1990 INTRODUCTION .. . . 331 THE PRECURSOR PROTEINS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 Targeting Signals 332 Translocation Competence 335 IMPORT RECEPTORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . .
Pfanner, Nikolaus, Neupert, Walter
openaire +4 more sources
Sorting of exclusive mitochondrial proteins from the Mitoproteome database
Bulletin of the National Research Centre, 2022 World Wide Web and scientific literature record information regarding several organelles and mitochondria is not an exception. However, currently mitochondrial databases also provide information about non-mitochondrial proteins.
Deepak Yadav +5 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Background: Metabolic syndrome (MS) is a global epidemic that has great socioeconomic and public health implications. This study reports observed effects of the Shexiang Baoxin Pill (SBP) in a rat model of MS and explores its underlying mechanisms of ...
Dan Wei +5 more
doaj +1 more source
Dual targeted mitochondrial proteins are characterized by lower MTS parameters and total net charge. [PDF]
PLoS ONE, 2008 BACKGROUND: In eukaryotic cells, identical proteins can be located in different subcellular compartments (termed dual-targeted proteins). METHODOLOGY/PRINCIPAL FINDINGS: We divided a reference set of mitochondrial proteins (published single gene studies)
Maya Dinur-Mills, Merav Tal, Ophry Pines
doaj +1 more source
Frontiers in Physiology, 2022 Mitochondria contain their own DNA, mitochondrial DNA, which encodes thirteen proteins. However, mitochondria require thousands of proteins encoded in the nucleus to carry out their many functions.
Aditya Sen, Aditya Sen, Rachel T. Cox
doaj +1 more source
Archives of Medical Science, 2019 Introduction One of the crucial mechanisms following spinal cord injury is mitochondria-associated cell death. Minocycline, an anti-inflammatory drug, is well known to impede mitochondrial cell death.
Guolei Zhang +3 more
doaj +1 more source
Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system [PDF]
Open Biology, 2017 Mitochondria are pivotal organelles in eukaryotic cells. The complex proteome of mitochondria comprises proteins that are encoded by nuclear and mitochondrial genomes. The biogenesis of mitochondrial proteins requires their transport in an unfolded state
Piotr Bragoszewski +2 more
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Cell Reports, 2023 Summary: In mammals, about 99% of mitochondrial proteins are synthesized in the cytosol as precursors that are subsequently imported into the organelle. The mitochondrial health and functions rely on an accurate quality control of these imported proteins.
Julie Lavie +11 more
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Mechanisms of Modulation of Mitochondrial Architecture
Biomolecules, 2023 Mitochondrial network architecture plays a critical role in cellular physiology. Indeed, alterations in the shape of mitochondria upon exposure to cellular stress can cause the dysfunction of these organelles.
Juan Pablo Muñoz +4 more
doaj +1 more source