Results 21 to 30 of about 910,991 (300)

ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway

Life Science Alliance, 2021
The GET pathway is required to target non-imported mitochondrial carrier proteins to the endoplasmic reticulum, which prevents their deposition into Hsp42-dependent protein foci.
Tianyao Xiao, Viplendra PS Shakya, Adam L Hughes   +2 more
doaj   +1 more source

Mitochondrial molecular chaperones [PDF]

, 1994
After synthesis in the cytosol, most mitochondrial proteins must traverse mitochondrial membranes to reach their functional location. During this process, proteins become unfolded and then refold to attain their native conformation after crossing the ...
Atencio, Caplan, Caplan, Cheng, Craig, Cyr, Deshales, Eilers, Gambill, Glick, Glick, Hartl, Hartl, Hwang, Johnson, Kang, Kiebler, Langer, Liberek, Manning-Krieg, Neupert, Ostermann, Palleros, Rassow, Rospert, Sanders, Scherer, Schleyer, Schröder, Simon, Vestweber, Voos, Xia   +32 more
core   +1 more source

Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]

, 2006
The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial ...
Abdul, Appleby, Armstrong, Bai, Bourges, Buchet, Chai, Claros, Da Cruz, Dey, Du, Garcia, Gianazza, Joseph, King, King, Lescuyer, Luche, Manjasetty, Martinus, Perkins, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Santoni, Sharma, Sharp, Sherer, Singh, Sinha, Suzuki, Tastet, Taylor, Tryoen-Toth, Ugalde, Wiedemann, Zamzami, Zischka   +39 more
core   +4 more sources

RNAi-based gene silencing in primary mouse and human adipose tissues

Journal of Lipid Research, 2007
Cultured adipocyte cell lines are a model system widely used to study adipose function, but they exhibit significant physiological differences compared with primary cells from adipose tissue.
Vishwajeet Puri, Abhijit Chakladar, Joseph V. Virbasius, Silvana Konda, Aimee M. Powelka, My Chouinard, G. Nana Hagan, Richard Perugini, Michael P. Czech   +8 more
doaj   +1 more source

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ades, Allmann, Ardail, Ardail, Ardail, Attardi, Baker, Biermans, Biermans, Brdiczka, Brdiczka, Eilers, Glick, Hackenbrock, Hackenbrock, Hackenbrock, Hartl, Hartl, Hines, Hwang, Kellems, Kiebler, Knoll, Lill, Lithgow, Malhotra, Martin, Marzuki, McEnery, Murakami, Nicolay, Ohlendieck, Pain, Pfanner, Pfanner, Pfanner, Pon, Rassow, Rassow, Rassow, Rojo, Schleyer, Schwaiger, Stuart, Suissa, Söllner, Söllner, Söllner, van Venetië, Vestweber, Vestweber, Vignais, Watson, Werner, Wienhues, Zara   +55 more
core   +1 more source

Sorting of exclusive mitochondrial proteins from the Mitoproteome database

Bulletin of the National Research Centre, 2022
World Wide Web and scientific literature record information regarding several organelles and mitochondria is not an exception. However, currently mitochondrial databases also provide information about non-mitochondrial proteins.
Deepak Yadav, Bharti Thakur, Deepak Kumar, Sheemona Chowdhary, Rajasri Bhattacharyya, Dibyajyoti Banerjee   +5 more
doaj   +1 more source

Kinetic Studies on the Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in Intact Cells of Neurospora crassa [PDF]

, 1977
The transport of cytoplasmically synthesized mitochondrial proteins was investigated in whole cells of Neurospora crassa, using dual labelling and immunological techniques.
Hallermayer, Gerhard, Neupert, Walter, Zimmermann, Richard   +2 more
core   +1 more source

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis [PDF]

Nucleic Acids Research, 2012
Mitochondrial ribosomes and translation factors co-purify with mitochondrial nucleoids of human cells, based on affinity protein purification of tagged mitochondrial DNA binding proteins. Among the most frequently identified proteins were ATAD3 and prohibitin, which have been identified previously as nucleoid components, using a variety of methods ...
He, J, Cooper, HM, Reyes, A, Di Re, M, Sembongi, H, Litwin, TR, Gao, J, Neuman, KC, Fearnley, IM, Spinazzola, A, Walker, JE, Holt, IJ   +11 more
openaire   +3 more sources

Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa [PDF]

, 1977
Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction.
Andrews T. M., Bingham R. W., Blair G. E., Davidian N. M., Dobberstein B., Dolken G., Gaitskhoki V. S., Godinot C., Gonzalez-Cadavid N. F., Gonzalez-Cadavid N. F., Grollmann A. P., Hallermayer G., Kadenbach B., Kadenbach B., Kadenbach B., Kellems R. E., Kellems R. E., Kellems R. E., Kellems R. E., Marra E., Milstein C., Morris A., O'Brien R. L., Pfaff E., Redman C. M., Shore G. C., Takanami M., Tata J. R., Weiss H., Wojtczak L., Wojtczak L.   +30 more
core   +1 more source

THE MITOCHONDRIAL PROTEIN IMPORT APPARATUS [PDF]

Annual Review of Biochemistry, 1990
INTRODUCTION .. . . 331 THE PRECURSOR PROTEINS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 Targeting Signals 332 Translocation Competence 335 IMPORT RECEPTORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . .
Pfanner, Nikolaus, Neupert, Walter
openaire   +4 more sources