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Mitochondrial Dynamics in Mitochondrial Diseases
Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial ...
Juan M. Suárez-Rivero +9 more
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Players in Mitochondrial Dynamics and Female Reproduction
Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and mitochondrial quality control.
Weiwei Zou +12 more
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Correcting abnormal mitochondrial dynamics to facilitate tumor treatment
Mitochondrial dynamics are closely related to various cellular physiological activities, including cell proliferation, homeostasis, and cell migration, and are regulated by a variety of enzymes, proteins and cytokines.
Bowen Yang, Yumeng Lin, Ying-Qiang Shen
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Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu +7 more
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Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi +2 more
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There is growing evidence that mitochondrial dynamics play a role in mitochondrial function quality control. Recent studies have discovered that physical activity can aid in maintaining a healthy mitochondrial population and may even counteract the ...
Ángel J. Zamora-Ramírez +1 more
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Cardiac ischemia-reperfusion (I/R) injury is associated with mitochondrial dysfunction. Recent studies have reported that mitochondrial function is determined by mitochondrial dynamics.
Yuanyan Deng +5 more
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In neurodegenerative diseases, neurodegeneration has been related to several mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria, impaired mitophagy, and blocked mitochondria mitochondrial transport in axons.
Danying Yang +16 more
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Impacts of impaired mitochondrial dynamics in hearing loss: Potential therapeutic targets
Mitochondria are the powerhouse of the cells. Under physiological conditions, mitochondrial fission and fusion maintain a dynamic equilibrium in the cytoplasm, which is referred to as mitochondrial dynamics.
Tianyuan Zou +29 more
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Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are pivotal to tissue homeostasis, repair, and regeneration due to their potential for self-renewal, multilineage differentiation, and immune modulation.
Lin Ren +17 more
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