Results 1 to 10 of about 49,263 (303)

Mitochondrial fusion and fission in vascular disease

Hypertension Research
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FMRP gains mitochondrial fission control

Nature Cell Biology
Carissa L. Sirois, Soraya O. Sandoval, Xinyu Zhao   +2 more
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Mitochondrial Fission/Fusion

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Role of mitochondrial fission in stress susceptibility

Lab Animal
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Mitochondrial fission factor (MFF) frameshift variant in Bullmastiffs with mitochondrial fission encephalopathy [PDF]

Animal Genetics, 2022
AbstractFamilial cerebellar ataxia with hydrocephalus in Bullmastiffs was described almost 40 years ago as a monogenic autosomal recessive trait. We investigated two young Bullmastiffs showing similar clinical signs. They developed progressive gait and behavioural abnormalities with an onset at around 6 months of age.
Matthias Christen, Rodrigo Gutierrez‐Quintana, Helene Vandenberghe, Adriana Kaczmarska, Jacques Penderis, Roberto José‐López, Angie Rupp, Ian R. Griffiths, Vidhya Jagannathan, Tosso Leeb   +9 more
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Elastocapillary Instability in Mitochondrial Fission [PDF]

Physical Review Letters, 2015
Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. Here we propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission.
Gonzalez-Rodriguez, David, Sart, Sébastien, Babataheri, Avin, Tareste, David, Barakat, Abdul, Clanet, Christophe, Husson, Julien   +6 more
openaire   +8 more sources

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

Membranes, 2022
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi, Azza Salah, Ayman W. El-Hattab   +2 more
doaj   +3 more sources

Mitochondrial fusion, fission, and mitochondrial toxicity [PDF]

Toxicology, 2017
Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as well as processes such as intracellular transport. These processes maintain mitochondrial homeostasis, regulate mitochondrial form, volume and function, and are increasingly ...
Joel N Meyer, Anthony L Luz
exaly   +3 more sources

Deceleration of fusion-fission cycles improves mitochondrial quality control during aging. [PDF]

PLoS Computational Biology, 2012
Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer.
Marc Thilo Figge, Andreas S Reichert, Michael Meyer-Hermann, Heinz D Osiewacz   +3 more
doaj   +2 more sources

Mitochondrial membrane tension governs fission [PDF]

Cell Reports, 2018
Abstract During mitochondrial fission, key molecular and cellular factors assemble on the outer mitochondrial membrane, where they coordinate to generate constriction. Constriction sites can eventually divide, or reverse upon disassembly of the machinery. However, a role for membrane tension in mitochondrial fission, although speculated,
Mahecic, Dora, Carlini, Lina, Kleele, Tatjana, Colom Diego, Adai, Goujon, Antoine, Matile, Stefan, Roux, Aurélien, Manley, Suliana   +7 more
core   +8 more sources