Results 11 to 20 of about 1,174,031 (334)
Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders
Membranes, 2022 Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi +2 more
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Mitochondrial fission factor (MFF) frameshift variant in Bullmastiffs with mitochondrial fission encephalopathy [PDF]
Animal Genetics, 2022 AbstractFamilial cerebellar ataxia with hydrocephalus in Bullmastiffs was described almost 40 years ago as a monogenic autosomal recessive trait. We investigated two young Bullmastiffs showing similar clinical signs. They developed progressive gait and behavioural abnormalities with an onset at around 6 months of age.
Matthias Christen +9 more
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Pharmacological Research, 2023 Dysregulated mitochondrial metabolism occurs in several pathological processes characterized by cell proliferation and migration. Nonetheless, the role of mitochondrial fission is not well appreciated in cardiac fibrosis, which is accompanied by enhanced
Bin Tu +13 more
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Cell Death and Disease, 2022 Previous studies have demonstrated dysregulated mitochondrial dynamics in fibrotic livers and hepatocytes. Little is currently known about how mitochondrial dynamics are involved, nor is it clear how mitochondrial dynamics participate in hepatic stellate
Yanni Zhou +8 more
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International Journal of Molecular Sciences, 2023 Mitochondria, the membrane-bound cell organelles that supply most of the energy needed for cell function, are highly regulated, dynamic organelles bearing the ability to alter both form and functionality rapidly to maintain normal physiological events ...
Nir Qvit
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Molecular Cell, 2023 SUMMARY Mitophagy plays an important role in mitochondrial homeostasis by selective degradation of mitochondria. During mitophagy, mitochondria should be fragmented to allow engulfment within autophagosomes, whose capacity is exceeded by the typical ...
Tomotake Kanki, Tetsu Saigusa
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Mitochondrial Fission, Fusion, and Stress [PDF]
Science, 2012 Mitochondrial Dynamics Mitochondria—the powerhouses of the cell—are autonomous organelles with their own genomes. Within cells, mitochondria are remarkably dynamic, continually moving around the cytoplasm and undergoing fusion and fission reactions ...
R. Youle, A. M. van der Bliek
semanticscholar +3 more sources
Elastocapillary Instability in Mitochondrial Fission [PDF]
Physical Review Letters, 2015 Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. Here we propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission.
Gonzalez-Rodriguez, David +6 more
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Cancer Communications, 2022 Mitochondria are dynamic organelles that constantly change their morphology through fission and fusion processes. Recently, abnormally increased mitochondrial fission has been observed in several types of cancer.
Tao Yang, Jinliang Xing, Jibin Li
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Antioxidants, 2023 Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal physiology and under conditions of stress. Its dysregulation has been associated with several metabolic diseases, including, but not limited to, obesity, type 2 ...
Tianzheng Yu +3 more
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