Results 21 to 30 of about 49,263 (303)
Nature Communications, 2023 Mitochondrial morphology, which is controlled by mitochondrial fission and fusion, is an important regulator of the thermogenic capacity of brown adipocytes.
Donghua Hu +11 more
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Mitochondrial Fission, Fusion, and Stress [PDF]
Science, 2012 Mitochondrial Dynamics Mitochondria—the powerhouses of the cell—are autonomous organelles with their own genomes. Within cells, mitochondria are remarkably dynamic, continually moving around the cytoplasm and undergoing fusion and fission reactions. Youle and van der Bliek (p. 1062 )
Richard J, Youle +1 more
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PLoS Genetics, 2020 Balanced mitochondrial fission and fusion play an important role in shaping and distributing mitochondria, as well as contributing to mitochondrial homeostasis and adaptation to stress.
Ana Terriente-Felix +2 more
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Mechanisms of Mitochondrial Fission and Fusion [PDF]
Cold Spring Harbor Perspectives in Biology, 2013 Mitochondria continually change shape through the combined actions of fission, fusion, and movement along cytoskeletal tracks. The lengths of mitochondria and the degree to which they form closed networks are determined by the balance between fission and fusion rates. These rates are influenced by metabolic and pathogenic conditions inside mitochondria
Alexander M, van der Bliek +2 more
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A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
Cell Reports, 2021 Summary: Mitochondria are highly dynamic organelles subjected to fission and fusion events. During mitosis, mitochondrial fission ensures equal distribution of mitochondria to daughter cells. If and how this process can actively drive mitotic progression
Evanthia Pangou +15 more
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New therapeutic directions in type II diabetes and its complications: mitochondrial dynamics
Frontiers in Endocrinology, 2023 As important organelles of energetic and metabolism, changes in the dynamic state of mitochondria affect the homeostasis of cellular metabolism. Mitochondrial dynamics include mitochondrial fusion and mitochondrial fission.
Shengnan Wang +7 more
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Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. [PDF]
PLoS ONE, 2017 Adipocyte differentiation is regulated by intracellular reactive oxygen species (ROS) generation and mitochondrial fission and fusion processes. However, the correlation between intracellular ROS generation and mitochondrial remodeling during adipocyte ...
Jung-Hak Kim +5 more
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Pharmacological Research, 2023 Dysregulated mitochondrial metabolism occurs in several pathological processes characterized by cell proliferation and migration. Nonetheless, the role of mitochondrial fission is not well appreciated in cardiac fibrosis, which is accompanied by enhanced
Bin Tu +13 more
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An Ancient Fission of Mitochondrial cox1 [PDF]
Molecular Biology and Evolution, 2009 Many genes inherited from the alpha-proteobacterial ancestor of mitochondria have undergone evolutionary transfer to the nuclear genome in eukaryotes. In some rare cases, genes have been functionally transferred in pieces, resulting in split proteins that presumably interact in trans within mitochondria, fulfilling the same role as the ancestral ...
Ryan M R, Gawryluk, Michael W, Gray
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Mitochondrial morphological features are associated with fission and fusion events. [PDF]
PLoS ONE, 2014 Mitochondria are dynamic organelles that undergo constant remodeling through the regulation of two opposing processes, mitochondrial fission and fusion.
Laura M Westrate +4 more
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