Results 1 to 10 of about 4,246 (265)
TMEM16F and dynamins control expansive plasma membrane reservoirs
Nature Communications, 2021 Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane
Christine Deisl +3 more
doaj +2 more sources
Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]
Microbial Cell, 2016 The dynamins represent a superfamily of proteins that have been shown to function in a wide range of membrane fusion and fission events. An increasing number of mutations in the human classical dynamins, Dyn-1 and Dyn-2 has been reported, with diseases ...
Laila Moustaq +4 more
doaj +6 more sources
Mesoscopic elasticity controls dynamin-driven fission of lipid tubules [PDF]
Scientific ReportsMesoscale physics bridges the gap between the microscopic degrees of freedom of a system and its large-scale continuous behavior and highlights the role of a few key quantities in complex and multiscale phenomena, like dynamin-driven fission of lipid ...
Marco Bussoletti +4 more
doaj +2 more sources
Journal of Cell Science, 2009 The superfamily of dynamins includes classical dynamins and dynamin-related proteins. Classical dynamins are proteins that share sequence similarity with the first described dynamin, which is a large GTPase with five characteristic domains.
Jenny E Hinshaw
exaly +3 more sources
Biogenesis, inheritance, and 3D ultrastructure of the microsporidian mitosome [PDF]
Life Science AllianceQuantitative electron and light microscopy combined with bioinformatics reveal that microsporidian mitosomes grow and divide incrementally and are inherited at the microsporidian centrosome (spindle pole body), whereas mitochondrial dynamins participate ...
Christian Hacker +10 more
doaj +2 more sources
Dynamins maintain nuclear envelope homeostasis and genome stability
Nature CommunicationsThe nuclear envelope is a protective barrier for the genome and a mechanotransduction interface between cytoplasm and nucleus, whose malfunction disrupts nucleocytoplasmic transport, compromises DNA repair, accelerates telomere shortening, and promotes ...
Célia Aveleira +13 more
doaj +2 more sources
The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum [PDF]
mBioDynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events. Plasmodium falciparum encodes three dynamin-like proteins whose functions are poorly understood.
Alexander A. Morano +5 more
doaj +2 more sources
Organelle Dynamics in Apicomplexan Parasites
mBio, 2021 Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate through endodyogeny, during which two daughter cells are formed within the ...
Julie M. J. Verhoef +2 more
doaj +1 more source
Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. [PDF]
J PhysiolAfuwape OAT +4 more
europepmc +2 more sources
mBio, 2023 The dynamin-like protein DnmA and its receptor FisA are essential for mitochondrial division in the fungus Aspergillus nidulans. Our research has demonstrated that H2O2 triggers significant changes in mitochondrial morphology, including constriction ...
Verónica Garrido-Bazán +3 more
doaj +1 more source