Results 1 to 10 of about 3,125 (107)
Dynamins maintain nuclear envelope homeostasis and genome stability [PDF]
Nature CommunicationsThe nuclear envelope is a protective barrier for the genome and a mechanotransduction interface between cytoplasm and nucleus, whose malfunction disrupts nucleocytoplasmic transport, compromises DNA repair, accelerates telomere shortening, and promotes ...
Ira Milosevic +2 more
exaly +3 more sources
Role of GTPase-Dependent Mitochondrial Dynamins in Heart Diseases
Frontiers in Cardiovascular Medicine, 2021 Heart function maintenance requires a large amount of energy, which is supplied by the mitochondria. In addition to providing energy to cardiomyocytes, mitochondria also play an important role in maintaining cell function and homeostasis.
Youyou Yan
exaly +3 more sources
TMEM16F and dynamins control expansive plasma membrane reservoirs
Nature Communications, 2021 Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane
Michael Fine +2 more
exaly +2 more sources
Mesoscopic elasticity controls dynamin-driven fission of lipid tubules [PDF]
Scientific ReportsMesoscale physics bridges the gap between the microscopic degrees of freedom of a system and its large-scale continuous behavior and highlights the role of a few key quantities in complex and multiscale phenomena, like dynamin-driven fission of lipid ...
Marco Bussoletti +4 more
doaj +2 more sources
The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum [PDF]
mBioDynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events. Plasmodium falciparum encodes three dynamin-like proteins whose functions are poorly understood.
Alexander A. Morano +5 more
doaj +2 more sources
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3 [PDF]
Journal of NeuroscienceVadim Arshavsky +2 more
exaly +2 more sources
Organelle Dynamics in Apicomplexan Parasites
mBio, 2021 Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate through endodyogeny, during which two daughter cells are formed within the ...
Julie M. J. Verhoef +2 more
doaj +1 more source
mBio, 2023 The dynamin-like protein DnmA and its receptor FisA are essential for mitochondrial division in the fungus Aspergillus nidulans. Our research has demonstrated that H2O2 triggers significant changes in mitochondrial morphology, including constriction ...
Verónica Garrido-Bazán +3 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2023 In eukaryotes, dynamins and dynamin-related proteins (DRPs) are high–molecular weight GTPases responsible for mechanochemical fission of organelles or membranes.
Gayani Ekanayake +3 more
doaj +1 more source
Cardiolipin targets a dynamin-related protein to the nuclear membrane
eLife, 2021 Dynamins are targeted to specific cellular membranes that they remodel via membrane fusion or fission. The molecular basis of conferring specificity to dynamins for their target membrane selection is not known.
Usha Pallabi Kar +2 more
doaj +1 more source