Results 1 to 10 of about 233,575 (303)

Role of Spectrin in Endocytosis

open access: yesCells, 2022
Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
doaj   +2 more sources

Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles

open access: yesInternational Journal of Nanomedicine, 2019
Noriaki Nagai,1 Fumihiko Ogata,1 Hiroko Otake,1 Yosuke Nakazawa,2 Naohito Kawasaki1 1Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan; 2Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan Purpose: We previously ...
Nagai N   +4 more
doaj   +1 more source

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

open access: yesFrontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka   +3 more
doaj   +1 more source

Transsynaptic N-Cadherin Adhesion Complexes Control Presynaptic Vesicle and Bulk Endocytosis at Physiological Temperature

open access: yesFrontiers in Cellular Neuroscience, 2021
At mammalian glutamatergic synapses, most basic elements of synaptic transmission have been shown to be modulated by specific transsynaptic adhesion complexes.
Sushma Dagar   +2 more
doaj   +1 more source

Emerging roles of proximal tubular endocytosis in renal fibrosis

open access: yesFrontiers in Cell and Developmental Biology, 2023
Endocytosis is a crucial component of many pathological conditions. The proximal tubules are responsible for reabsorbing the majority of filtered water and glucose, as well as all the proteins filtered through the glomerular barrier via endocytosis ...
Min Chen   +3 more
doaj   +1 more source

Endocytosis-Like Vesicle Fission Mediated by a Membrane-Expanding Molecular Machine Enables Virus Encapsulation for In Vivo Delivery

open access: yes, 2023
Biological membranes are functionalized by membrane-associated protein machinery. Membrane-associated transport processes, such as endocytosis, represent a fundamental and universal function mediated by membrane-deforming protein machines, by which small
Ken Yoshizawa (14691376)   +16 more
core   +6 more sources

The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications

open access: yesCells, 2023
Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss
Olga Klaudia Szewczyk-Roszczenko   +8 more
doaj   +1 more source

Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking

open access: yesCells, 2022
Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It occurs via a variety of mechanisms and involves many regulatory proteins.
Chayanika Gundu   +7 more
doaj   +1 more source

The coiled-coil domain of EHD2 mediates inhibition of LeEix2 endocytosis and signaling. [PDF]

open access: yesPLoS ONE, 2009
Endocytosis has been suggested to be crucial for the induction of plant immunity in several cases. We have previously shown that two Arabidopsis proteins, AtEHD1 and AtEHD2, are involved in endocytosis in plant systems. AtEHD2 has an inhibitory effect on
Maya Bar   +3 more
doaj   +1 more source

Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles

open access: yesiScience, 2022
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane.
Gianvito Arpino   +9 more
doaj   +1 more source

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