Results 21 to 30 of about 249,281 (299)

An ultrasensitive sorting mechanism for EGF receptor endocytosis [PDF]

, 2008
Background The EGF receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling ...
Roland Eils, Hoeller, Daniela, Ivayla Vacheva, Schmidt-Glenewinkel, Hannah, Eils, Roland, Hannah Schmidt-Glenewinkel, Đikić, Ivan, Vacheva, Ivayla, Daniela Hoeller, Ivan Dikic   +9 more
core   +1 more source

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Pickersgill, L, Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, Jackson, KG, J. Panovska, Panovska, J., O'Malley, B., Pickersgill, L., Wattis, J.A.D., Jackson, K.G., Blackburn, H., Byrne, H.M.   +22 more
core   +1 more source

A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis. [PDF]

PLoS ONE, 2012
BACKGROUND: Presynaptically neurotoxic phospholipases A(2) inhibit synaptic vesicle recycling through endocytosis. PRINCIPAL FINDINGS: Here we provide insight into the action of a presynaptically neurotoxic phospholipase A(2) ammodytoxin A (AtxA) on ...
Mojca Mattiazzi, Yidi Sun, Heimo Wolinski, Andrej Bavdek, Toni Petan, Gregor Anderluh, Sepp D Kohlwein, David G Drubin, Igor Križaj, Uroš Petrovič   +9 more
doaj   +1 more source

Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits [PDF]

, 1991
The clustering of plasma membrane receptors in clathrin-coated pits depends on determinants within their cytoplasmic domains. In several cases, individual tyrosine residues were shown to be necessary for rapid internalization.
Geffen, I, M Spiess, Spiess, M, Fuhrer, C., C Fuhrer, Spiess, M., I Geffen, Geffen, I., Fuhrer, Christian; https://orcid.org/   +8 more
core   +1 more source

Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses

Cell Reports, 2019
Summary: At presynaptic terminals, neurotransmitters are released by synaptic vesicle exocytosis at the active zone. In order to maintain efficient neurotransmission and proper synaptic structure, sites of vesicle fusion must be cleared rapidly by ...
Marta Orlando, Dietmar Schmitz, Christian Rosenmund, Melissa A. Herman   +3 more
doaj   +1 more source

Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

Cellular Physiology and Biochemistry, 2014
Background: In intestinal epithelial cells, acute regulation of the brush border Na+/H+ exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin.
Nicholas C. Zachos, Bharath Alamelumangpuram, Luke J. Lee, Peng Wang, Olga Kovbasnjuk   +4 more
doaj   +1 more source

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes [PDF]

, 2007
Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival.
Peacock, Lori, Field, Mark C, Natesan, Senthil Kumar A, Matthews, K, Peacock, L, Gibson, W, Matthews, Keith; id_orcid, Natesan, Senthil, Field, MC, Gibson, Wendy   +9 more
core   +1 more source

Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]

, 2003
Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C., Gupta, A.K., Curtis, A.S.G., Gupta, M.   +3 more
core   +1 more source

Analysis of endocytosis at eisosomes [PDF]

, 2011
The yeast plasma membrane contains at least three microdomains – membrane compartment containing Pma1 (MCP), membrane compartment containing TORC2 (MCT) and membrane compartment containing Can1 (MCC).
Rehman, Michael, Rehman, M.
core   +1 more source

Specific Aptamer-Based Probe for Analyzing Biomarker MCP Entry Into Singapore Grouper Iridovirus-Infected Host Cells via Clathrin-Mediated Endocytosis

Frontiers in Microbiology, 2020
Biomarkers have important roles in various physiological functions and disease pathogenesis. As a nucleocytoplasmic DNA virus, Singapore grouper iridovirus (SGIV) causes high economic losses in the mariculture industry.
Qing Yu, Mingzhu Liu, Siting Wu, Siting Wu, Xinxian Wei, Hehe Xiao, Yi Yi, Hao Cheng, Shaowen Wang, Qin Zhang, Qiwei Qin, Pengfei Li   +11 more
doaj   +1 more source