Results 11 to 20 of about 233,575 (303)
Endocytosis of coacervates into liposomes
Journal of the American Chemical Society, 2022 Recent studies have shown that the interactions between condensates and biological membranes is of functional importance. Here, we study how the interaction between complex coacervates and liposomes as model systems can lead to membrane deformation and ...
Tiemei, Lu +6 more
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Physiological Reviews, 1997 Mammalian cells take up extracellular material by a variety of different mechanisms that are collectively termed endocytosis. Endocytic mechanisms serve many important cellular functions including the uptake of extracellular nutrients, regulation of ...
F. R. Maxfield +2 more
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Cold Spring Harbor Perspectives in Biology, 2013 Endocytosis entails selective packaging of cell-surface proteins, such as receptors for cytokines and adhesion components, in cytoplasmic vesicles (endosomes). The series of sorting events that determines the fate of internalized proteins, either degradation in lysosomes or recycling back to the plasma membrane, relies on intrinsic sequence motifs ...
Mellman I, Yarden Y
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A Doubleheader in Endocytosis [PDF]
Neuron, 2007 Synaptojanin1 degrades the signaling lipid phosphatidylinositol-4,5-bisphosphate and facilitates compensatory endocytosis, clathrin-coat disassembly, and vesicle reavailability at active synapses. In this issue of Neuron, Mani et al. provide new information about the separate roles of synaptojanin's two phosphatase domains and its interactions with ...
Zanazzi, George, Matthews, Gary
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Developmental Cell, 2003 Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction ...
Halford, Michael M +2 more
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Plant Signaling & Behavior, 2008 Endocytosis regulates many important and diverse processes in eukaryotic life. EH domain containing proteins function as regulators of endocytosis through protein-protein interactions. Several interactors of mammalian EHDs were identified, including clathrin machinery components.
Maya, Bar +3 more
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Cell Reports, 2013 Rapid endocytosis, which takes only a few seconds, is widely observed in secretory cells. Although it is more efficient in recycling vesicles than in slow clathrin-mediated endocytosis, its underlying mechanism, thought to be clathrin independent, is ...
Jianhua Xu +7 more
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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis [PDF]
, 2014 Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic.
Willox, Anna K. +5 more
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Regulation of EGFR Endocytosis by CBL During Mitosis
Cells, 2018 The overactivation of epidermal growth factor (EGF) receptor (EGFR) is implicated in various cancers. Endocytosis plays an important role in EGFR-mediated cell signaling.
Ping Wee, Zhixiang Wang
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An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]
, 2014 Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding +9 more
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