Results 11 to 20 of about 249,281 (299)
Physiological Reviews, 1997 Mammalian cells take up extracellular material by a variety of different mechanisms that are collectively termed endocytosis. Endocytic mechanisms serve many important cellular functions including the uptake of extracellular nutrients, regulation of cell-surface receptor expression, maintenance of cell polarity, and antigen presentation.
S, Mukherjee, R N, Ghosh, F R, Maxfield
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International Journal of Nanomedicine, 2019 Noriaki Nagai,1 Fumihiko Ogata,1 Hiroko Otake,1 Yosuke Nakazawa,2 Naohito Kawasaki1 1Faculty of Pharmacy, Kindai University, Higashi-Osaka 577-8502, Japan; 2Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan Purpose: We previously ...
Nagai N +4 more
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Trends in Cell Biology, 1993 The presence of an endocytic pathway in cells from a wide range of species and the conservation of the proteins involved in this process throughout evolution suggest that endocytosis is of fundamental importance for the eukaryotic cell. However, some surprising recent results have shown that both Dictyostelium discoideum and Saccharomyces cerevisiae ...
Riezman H
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Cold Spring Harbor Perspectives in Biology, 2013 Endocytosis entails selective packaging of cell-surface proteins, such as receptors for cytokines and adhesion components, in cytoplasmic vesicles (endosomes). The series of sorting events that determines the fate of internalized proteins, either degradation in lysosomes or recycling back to the plasma membrane, relies on intrinsic sequence motifs ...
Mellman I, Yarden Y
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Exocytosis and Endocytosis [PDF]
The Plant Cell, 1999 Exocytosis is a general term used to denote vesicle fusion at the plasma membrane, and it is the final step in the secretory pathway that typically begins in the endoplasmic reticulum (ER), passes through the Golgi apparatus, and ends at the outside of the cell.
, Battey +3 more
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Plant Signaling & Behavior, 2008 Endocytosis regulates many important and diverse processes in eukaryotic life. EH domain containing proteins function as regulators of endocytosis through protein-protein interactions. Several interactors of mammalian EHDs were identified, including clathrin machinery components.
Maya, Bar +3 more
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Developmental Cell, 2003 Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction ...
Halford, Michael M +2 more
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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis [PDF]
, 2014 Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic.
Willox, Anna K. +5 more
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A Doubleheader in Endocytosis [PDF]
Neuron, 2007 Synaptojanin1 degrades the signaling lipid phosphatidylinositol-4,5-bisphosphate and facilitates compensatory endocytosis, clathrin-coat disassembly, and vesicle reavailability at active synapses. In this issue of Neuron, Mani et al. provide new information about the separate roles of synaptojanin's two phosphatase domains and its interactions with ...
Zanazzi, George, Matthews, Gary
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An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]
, 2014 Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding +9 more
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