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Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers [PDF]
Cell Reports, 2012 Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the ...
Comert Kural +6 more
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Dynamics of the formation of flat clathrin lattices in response to growth factor stimulus. [PDF]
PLoS Computational BiologyClathrin assemblies on the cell membrane are critical for endocytosis and signal transduction in cells. Specifically, the Ω-shaped clathrin assembly functions as the coat of endocytic vesicles, while the flat clathrin assembly, also known as the flat ...
Lingxia Qiao +3 more
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Clathrin in mitotic spindles [PDF]
American Journal of Physiology-Cell Physiology, 2000 Subconfluent cultures of Madin-Darby canine kidney (MDCK) and CV-1 cells were immunostained with two monoclonal antibodies (MAbs), MAb X-22 and MAb 23, against clathrin heavy chain and with polyclonal antiserum against a conserved region of all mammalian clathrin light chains.
C T, Okamoto, J, McKinney, Y Y, Jeng
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Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks [PDF]
Nature CommunicationsClathrin-mediated endocytosis is essential for membrane traffic, impacting a diverse range of cellular processes including cell signaling homeostasis, cell adhesion, and receptor recycling.
Brandon T. Malady +10 more
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Clathrin Independent Endocytosis [PDF]
, 2016 The existence of endocytic pathways that do not rely on the coat protein clathrin have been known for some time. However, until recently the mechanisms involved in these pathways, as well as their functions, cargoes, and dynamics were largely unknown. Recent advances are leading to a new understanding of the magnitude of clathrin-independent pathways ...
Parton, R. G., R.G. Parton
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A CIE change in our understanding of endocytic mechanisms
Frontiers in Cell and Developmental Biology, 2023 The past six decades have seen major advances in our understanding of endocytosis, ranging from descriptive studies based on electron microscopy to biochemical and genetic characterization of factors required for vesicle formation.
Daniel J. Rioux +2 more
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A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly. [PDF]
PLoS ONE, 2016 The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin binding motifs to assemble clathrin triskelia into cages. However, the precise mechanism of clathrin assembly is not yet known.
Lia Moshkanbaryans +4 more
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Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses
eLife, 2022 At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity.
Lisa AE Catsburg +3 more
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Frontiers in Synaptic Neuroscience, 2022 Four modes of endocytosis and subsequent synaptic vesicle (SV) recycling have been described at the presynapse to ensure the availability of SVs for synaptic release.
Alp Paksoy +5 more
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Clathrin exchange during clathrin-mediated endocytosis [PDF]
The Journal of Cell Biology, 2001 During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical, there must be a structural rearrangement of clathrin as invagination occurs.
Wu, Xufeng +5 more
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