The ∼ 16 kDa C-terminal sequence of clathrin assembly protein AP180 is essential for efficient clathrin binding. [PDF]
PLoS ONE, 2014 Brain-specific AP180 is present in clathrin coats at equal concentration to the adapter complex, AP2, and assembles clathrin faster than any other protein in vitro.
Ling-Shan Chan +3 more
doaj +1 more source
A functional study of AUXILIN-LIKE1 and 2, two putative clathrin uncoating factors in Arabidopsis [PDF]
, 2018 Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME is essential for many developmental and physiological
Adamowski, Maciek +5 more
core +2 more sources
Clathrin-dependent endocytosis [PDF]
Biochemical Journal, 2004 The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
Seyed Ali, Mousavi +3 more
openaire +2 more sources
Clathrin Adaptor Complex-interacting Protein Irc6 Functions through the Conserved C-Terminal Domain. [PDF]
, 2019 Clathrin coats drive transport vesicle formation from the plasma membrane and in pathways between the trans-Golgi network (TGN) and endosomes. Clathrin adaptors play central roles orchestrating assembly of clathrin coats.
Costaguta, Giancarlo +2 more
core +2 more sources
Clathrin Heavy Chain subunits coordinate endo- and exocytic traffic and affect stomatal movement [PDF]
, 2017 The current model for vesicular traffic to and from the plasma membrane is accepted but the molecular requirements for this coordination are not well defined.
Blatt, Michael R. +4 more
core +2 more sources
eLife, 2014 The discovery of an ancient protein complex reveals the evolutionary relationships between the proteins that help to form vesicles.
Thomas U Schwartz
doaj +1 more source
Brain clathrin and clathrin-associated proteins. [PDF]
Biochemical Journal, 1982 The assembly of clathrin into baskets or cages in vitro may depend on formation of complex between clathrin and a polypeptide doublet migrating in the 30000-mol.wt. region. Clathrin with several associated proteins was isolated from coated-vesicle fractions of bovine cerebral cortex.
M P, Lisanti +4 more
openaire +2 more sources
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
, 2007 Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core +1 more source
Flat clathrin lattices are linked to metastatic potential in colorectal cancer
iScience, 2023 Summary: Clathrin assembles at the cells’ plasma membrane in a multitude of clathrin-coated structures (CCSs). Among these are flat clathrin lattices (FCLs), alternative clathrin structures that have been found in specific cell types, including cancer ...
Charlotte Cresens +6 more
doaj +1 more source
The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells
Membranes, 2014 Receptor-mediated endocytosis in renal proximal tubule epithelial cells (PTECs) is important for the reabsorption and metabolization of proteins and other substances, including carrier-bound vitamins and trace elements, in glomerular filtrates ...
Shankhajit De +2 more
doaj +1 more source