A role for amphiphysin in AP-1/clathrin coat formation [PDF]
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. Clathrin, in combination with different adaptor proteins, is the major coat protein for vesicle formation at the plasma membrane, endosomes, and the ...
Huser Studer, Sonja
core +1 more source
Recruitment of AP-1 clathrin adaptors to liposomal membranes [PDF]
Protein and membrane traffic between organelles within the endocytic and exocytic pathway is mediated most prominently by coated vesicles. These vesicles are formed by the assembly of cytosolic coat proteins onto the donor membrane, which deform it into ...
Meyer, Daniel Markus
core +1 more source
An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy [PDF]
Current knowledge of the structural changes taking place during clathrin-mediated endocytosis is largely based on electron microscopy images of fixed preparations and x-ray crystallography data of purified proteins.
Merrifield, C.J. +40 more
core +1 more source
The ∼ 16 kDa C-terminal sequence of clathrin assembly protein AP180 is essential for efficient clathrin binding. [PDF]
Brain-specific AP180 is present in clathrin coats at equal concentration to the adapter complex, AP2, and assembles clathrin faster than any other protein in vitro.
Ling-Shan Chan +3 more
doaj +1 more source
A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin [PDF]
An essential stage in endocytic coated vesicle recycling is the dissociation of clathrin from the vesicle coat by the molecular chaperone, Hsc70 and the J-domain-containing protein, auxilin, in an ATP-dependent process.
Petr Kuzmic +14 more
core +1 more source
A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
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The discovery of an ancient protein complex reveals the evolutionary relationships between the proteins that help to form vesicles.
Thomas U Schwartz
doaj +1 more source
Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles [PDF]
Cryo-electron tomography reveals the conformational changes and clathrin interactions of AP2 during coated vesicle assembly.
Kovtun, Oleksiy +4 more
openaire +4 more sources
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation [PDF]
The interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved.
Cristina Gutiérrez-Caballero +11 more
core +1 more source
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly [PDF]
The self-assembly of the protein clathrin on biological membranes facilitates essential processes of endocytosis in biological systems and has provided a source of inspiration for materials design by the highly ordered structural appearance. By mimicking
Diana Sobota (6944451) +6 more
core +2 more sources

