Results 31 to 40 of about 80,290 (296)

Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]

open access: yes, 2010
This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Reynolds, A   +5 more
core   +1 more source

An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]

open access: yes, 2014
Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding   +9 more
core   +1 more source

The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells

open access: yesMembranes, 2014
Receptor-mediated endocytosis in renal proximal tubule epithelial cells (PTECs) is important for the reabsorption and metabolization of proteins and other substances, including carrier-bound vitamins and trace elements, in glomerular filtrates ...
Shankhajit De   +2 more
doaj   +1 more source

Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways [PDF]

open access: yes, 2013
Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment.
Peter Tompa   +11 more
core   +1 more source

A new role for clathrin adaptor proteins 1 and 3 in lipoplex trafficking [PDF]

open access: yes, 2014
Intracellular protein trafficking through secretory and endocytic pathways depends on the function of adaptor proteins that bind motifs on cargo proteins.
Gumbs, Jade   +7 more
core   +2 more sources

SNX4 in complex with clathrin and dynein: implications for endosome movement. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Sorting nexins (SNXs) constitute a family of proteins classified by their phosphatidylinositol (PI) binding Phox homology (PX) domain. Some members regulate intracellular trafficking.
Sigrid S Skånland   +3 more
doaj   +1 more source

Clathrin Light Chains: Not to Be Taken so Lightly

open access: yesFrontiers in Cell and Developmental Biology, 2021
Clathrin is a cytosolic protein involved in the intracellular trafficking of a wide range of cargo. It is composed of three heavy chains and three light chains that together form a triskelion, the subunit that polymerizes to form a clathrin coated ...
Jyoti Das   +4 more
doaj   +1 more source

Clathrin-independent, cholesterol and dynamin-dependent uptake of B19V in MDCK II cells.

open access: yes, 2023
MDCK II cells grown on TC inserts were pre-treated for 30 min with drugs interfering with clathrin, caveolae-mediated endocytosis, and dynamin function, and infected with B19V at pH 6.1.
Corinne Suter (15853142)   +5 more
core   +1 more source

Characterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivo.

open access: yesPLoS ONE, 2010
Clathrin and clathrin-dependent events are evolutionary conserved although it is believed that there are differences in the requirement for clathrin in yeast and higher vertebrates. Clathrin is a long-lived protein and thus, with clathrin knockdowns only
Petra Neumann-Staubitz   +3 more
doaj   +1 more source

Clathrin-dependent endocytosis [PDF]

open access: yesBiochemical Journal, 2004
The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
Seyed Ali, Mousavi   +3 more
openaire   +2 more sources

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