eLife, 2014 The discovery of an ancient protein complex reveals the evolutionary relationships between the proteins that help to form vesicles.
Thomas U Schwartz
doaj +1 more source
An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]
, 2014 Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding +9 more
core +1 more source
Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles [PDF]
Science Advances, 2020 Cryo-electron tomography reveals the conformational changes and clathrin interactions of AP2 during coated vesicle assembly.
Kovtun, Oleksiy +4 more
openaire +4 more sources
Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]
, 2010 This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Reynolds, A +5 more
core +1 more source
Transmission electron microscopy of a chc1 (clathrin) mutant in yeast [PDF]
, 2012 Electron micrographs of chc1 (clathrin heavy chain) mutant yeast cells.
Ethan Perlstein (97610) +1 more
core +1 more source
The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells
Membranes, 2014 Receptor-mediated endocytosis in renal proximal tubule epithelial cells (PTECs) is important for the reabsorption and metabolization of proteins and other substances, including carrier-bound vitamins and trace elements, in glomerular filtrates ...
Shankhajit De +2 more
doaj +1 more source
Flat clathrin lattices are linked to metastatic potential in colorectal cancer
iScience, 2023 Summary: Clathrin assembles at the cells’ plasma membrane in a multitude of clathrin-coated structures (CCSs). Among these are flat clathrin lattices (FCLs), alternative clathrin structures that have been found in specific cell types, including cancer ...
Charlotte Cresens +6 more
doaj +1 more source
Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways [PDF]
, 2013 Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment.
Peter Tompa +11 more
core +1 more source
SNX4 in complex with clathrin and dynein: implications for endosome movement. [PDF]
PLoS ONE, 2009 BACKGROUND:Sorting nexins (SNXs) constitute a family of proteins classified by their phosphatidylinositol (PI) binding Phox homology (PX) domain. Some members regulate intracellular trafficking.
Sigrid S Skånland +3 more
doaj +1 more source
A new role for clathrin adaptor proteins 1 and 3 in lipoplex trafficking [PDF]
, 2014 Intracellular protein trafficking through secretory and endocytic pathways depends on the function of adaptor proteins that bind motifs on cargo proteins.
Gumbs, Jade +7 more
core +1 more source