Results 11 to 20 of about 64,892 (258)
Dynamics of the formation of flat clathrin lattices in response to growth factor stimulus. [PDF]
PLoS Computational BiologyClathrin assemblies on the cell membrane are critical for endocytosis and signal transduction in cells. Specifically, the Ω-shaped clathrin assembly functions as the coat of endocytic vesicles, while the flat clathrin assembly, also known as the flat ...
Lingxia Qiao +3 more
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Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers
Cell Reports, 2012 Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the ...
Comert Kural +6 more
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Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks [PDF]
Nature CommunicationsClathrin-mediated endocytosis is essential for membrane traffic, impacting a diverse range of cellular processes including cell signaling homeostasis, cell adhesion, and receptor recycling.
Brandon T. Malady +10 more
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A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly. [PDF]
PLoS ONE, 2016 The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin binding motifs to assemble clathrin triskelia into cages. However, the precise mechanism of clathrin assembly is not yet known.
Lia Moshkanbaryans +4 more
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A CIE change in our understanding of endocytic mechanisms
Frontiers in Cell and Developmental Biology, 2023 The past six decades have seen major advances in our understanding of endocytosis, ranging from descriptive studies based on electron microscopy to biochemical and genetic characterization of factors required for vesicle formation.
Daniel J. Rioux +2 more
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Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses
eLife, 2022 At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity.
Lisa AE Catsburg +3 more
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Frontiers in Synaptic Neuroscience, 2022 Four modes of endocytosis and subsequent synaptic vesicle (SV) recycling have been described at the presynapse to ensure the availability of SVs for synaptic release.
Alp Paksoy +5 more
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Clathrin exchange during clathrin-mediated endocytosis [PDF]
The Journal of Cell Biology, 2001 During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical, there must be a structural rearrangement of clathrin as invagination occurs.
Wu, Xufeng +5 more
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Clathrin Adaptor GGA1 Polymerizes Clathrin into Tubules [PDF]
Journal of Biological Chemistry, 2007 GGAs, a class of monomeric clathrin adaptors, are involved in the sorting of cargo at the trans-Golgi network of eukaryotic cells. They are modular structures consisting of the VHS, the GAT, hinge, and GAE domains, which have been shown to interact directly with cargo, ARF, clathrin, and accessory proteins, respectively.
Fang, Zhang +5 more
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Plants, 2023 Clathrin is an evolutionarily highly conserved evolutionary protein consisting of clathrin light chains (CLC) and clathrin heavy chains (CHC), and these form its basic structure. Clathrin is an important host factor in the process of viral infection.
Mengguo Yuan +7 more
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