Results 41 to 50 of about 80,290 (296)

Clathrin is essential for meiotic spindle function in oocytes [PDF]

, 2010
In the mammalian ovary, oocytes are arrested at prophase of meiosis I until a hormonal stimulus triggers resumption of meiosis. During the subsequent meiotic maturation process, which includes completion of the first meiotic division and formation of the
Biology of Reproductive Cells, Crystal and Structural Chemistry, Wieger Hemrika, Algemeen Onderzoek DGK, Roland A P Romijn, Dep Biochemie en Celbiologie, Bernard A J Roelen, Hemrika, W., van Haeften, T., Roelen, B.A.J., Colenbrander, B., Sub Crystal and Structural Chemistry, Dep Gezondheidszorg Landbouwhuisdieren, Romijn, R.A.P., Theo van Haeften, Ben Colenbrander, Stoorvogel, W., Willem Stoorvogel, Hölzenspies, J.J., Jurriaan J Hölzenspies   +19 more
core   +1 more source

Clathrin is spindle-associated but not essential for mitosis.

PLoS ONE, 2008
BackgroundClathrin is a multimeric protein involved in vesicle coat assembly. Recently clathrin distribution was reported to change during the cell cycle and was found to associate with the mitotic spindle.
Joana Borlido, Greg Veltri, Antony P Jackson, Ian G Mills   +3 more
doaj   +1 more source

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

Frontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka, Hiromitsu Tanaka, Junichiro Funahashi, Tomoo Hirano   +3 more
doaj   +1 more source

An ultrasensitive sorting mechanism for EGF receptor endocytosis [PDF]

, 2008
Background The EGF receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling ...
Roland Eils, Hoeller, Daniela, Ivayla Vacheva, Schmidt-Glenewinkel, Hannah, Eils, Roland, Hannah Schmidt-Glenewinkel, Đikić, Ivan, Vacheva, Ivayla, Daniela Hoeller, Ivan Dikic   +9 more
core   +1 more source

Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization.

PLoS Pathogens, 2009
Many viruses that enter cells by clathrin-dependent endocytosis are significantly larger than the dimensions of a typical clathrin-coated vesicle.
David K Cureton, Ramiro H Massol, Saveez Saffarian, Tomas L Kirchhausen, Sean P J Whelan   +4 more
doaj   +1 more source

Arabidopsis clathrin adaptor EPSIN1 but not MODIFIED TRANSPORT TO THE VACOULE1 contributes to effective plant immunity against pathogenic Pseudomonas bacteria

Plant Signaling & Behavior, 2023
In eukaryotes, EPSINs are Epsin N-terminal Homology (ENTH) domain-containing proteins that serve as monomeric clathrin adaptors at the plasma membrane (PM) or the trans-Golgi Network (TGN)/early endosomes (EE).
Kelly Mason, Erica LaMontagne-Mueller, Michael Sauer, Antje Heese   +3 more
doaj   +1 more source

Human Coronavirus 229E Uses Clathrin-Mediated Endocytosis as a Route of Entry in Huh-7 Cells

Biomolecules
Human coronavirus 229E (HCoV-229E) is an endemic coronavirus responsible for approximately one-third of “common cold” cases. To infect target cells, HCoV-229E first binds to its receptor on the cell surface and then can follow different pathways ...
Sabina Andreu, Inés Ripa, José Antonio López-Guerrero, Raquel Bello-Morales   +3 more
doaj   +1 more source

Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases

Frontiers in Cellular Neuroscience, 2022
Endocytosis is a process essential to the health and well-being of cell. It is required for the internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of cell signalling.
Kate L. Prichard, Nicholas S. O'Brien, Sari R. Murcia, Jennifer R. Baker, Adam McCluskey   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

"In vitro" reconstitution of "trans"-Golgi exit and the effect of GAG attachment on protein sorting [PDF]

, 2007
The trans-Golgi network is one of the main sorting stations for proteins and lipids in the eukaryotic endomembrane system. Yet, the mechanisms for sorting and transport out of the trans-Golgi network remain poorly understood.
Kobialka, Szymon
core   +1 more source