Results 41 to 50 of about 75,443 (301)

Clathrin Light Chains: Not to Be Taken so Lightly

Frontiers in Cell and Developmental Biology, 2021
Clathrin is a cytosolic protein involved in the intracellular trafficking of a wide range of cargo. It is composed of three heavy chains and three light chains that together form a triskelion, the subunit that polymerizes to form a clathrin coated ...
Jyoti Das, Jyoti Das, Mahak Tiwari, Mahak Tiwari, Deepa Subramanyam   +4 more
doaj   +1 more source

Clathrin is essential for meiotic spindle function in oocytes [PDF]

, 2010
In the mammalian ovary, oocytes are arrested at prophase of meiosis I until a hormonal stimulus triggers resumption of meiosis. During the subsequent meiotic maturation process, which includes completion of the first meiotic division and formation of the
Biology of Reproductive Cells, Crystal and Structural Chemistry, Wieger Hemrika, Algemeen Onderzoek DGK, Roland A P Romijn, Dep Biochemie en Celbiologie, Bernard A J Roelen, Hemrika, W., van Haeften, T., Roelen, B.A.J., Colenbrander, B., Sub Crystal and Structural Chemistry, Dep Gezondheidszorg Landbouwhuisdieren, Romijn, R.A.P., Theo van Haeften, Ben Colenbrander, Stoorvogel, W., Willem Stoorvogel, Hölzenspies, J.J., Jurriaan J Hölzenspies   +19 more
core   +1 more source

Clathrin-dependent endocytosis [PDF]

Biochemical Journal, 2004
The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
Seyed Ali, Mousavi, Lene, Malerød, Trond, Berg, Rune, Kjeken   +3 more
openaire   +2 more sources

WSSV enters hemocytes via pIgR-CaM-clathrin-mediated endocytosis. [PDF]

, 2019
A, B, CPZ, an inhibitor of clathrin-mediated endocytosis, was injected into shrimp, and the quantity of WSSV was detected using qPCR with vp28 as an indicator. C, Efficiency of Mjclathrin-RNAi in hemocytes and intestine was determined using qPCR.
Jie-Jie Sun (3603746), Ming-Chong Yang (3603743), Guo-Juan Niu (5700848), Xiao-Fan Zhao (32716), Ji-Dong Xu (5700842), Shuai Wang (109515), Zhong-Hua He (6308378), Jin-Xing Wang (32715)   +7 more
core   +1 more source

Large self-assembled clathrin lattices spontaneously disassemble without sufficient adaptor proteins.

PLoS Computational Biology, 2022
Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins.
Si-Kao Guo, Alexander J Sodt, Margaret E Johnson   +2 more
doaj   +1 more source

Clathrin is spindle-associated but not essential for mitosis.

PLoS ONE, 2008
BackgroundClathrin is a multimeric protein involved in vesicle coat assembly. Recently clathrin distribution was reported to change during the cell cycle and was found to associate with the mitotic spindle.
Joana Borlido, Greg Veltri, Antony P Jackson, Ian G Mills   +3 more
doaj   +1 more source

Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization.

PLoS Pathogens, 2009
Many viruses that enter cells by clathrin-dependent endocytosis are significantly larger than the dimensions of a typical clathrin-coated vesicle.
David K Cureton, Ramiro H Massol, Saveez Saffarian, Tomas L Kirchhausen, Sean P J Whelan   +4 more
doaj   +1 more source

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

Frontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka, Hiromitsu Tanaka, Junichiro Funahashi, Tomoo Hirano   +3 more
doaj   +1 more source

Arabidopsis clathrin adaptor EPSIN1 but not MODIFIED TRANSPORT TO THE VACOULE1 contributes to effective plant immunity against pathogenic Pseudomonas bacteria

Plant Signaling & Behavior, 2023
In eukaryotes, EPSINs are Epsin N-terminal Homology (ENTH) domain-containing proteins that serve as monomeric clathrin adaptors at the plasma membrane (PM) or the trans-Golgi Network (TGN)/early endosomes (EE).
Kelly Mason, Erica LaMontagne-Mueller, Michael Sauer, Antje Heese   +3 more
doaj   +1 more source

An ultrasensitive sorting mechanism for EGF receptor endocytosis [PDF]

, 2008
Background The EGF receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling ...
Roland Eils, Hoeller, Daniela, Ivayla Vacheva, Schmidt-Glenewinkel, Hannah, Eils, Roland, Hannah Schmidt-Glenewinkel, Đikić, Ivan, Vacheva, Ivayla, Daniela Hoeller, Ivan Dikic   +9 more
core   +1 more source