Results 61 to 70 of about 80,290 (296)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Synaptic vesicles are primed for fast clathrin-mediated endocytosis at the ribbon synapse
Frontiers in Molecular Neuroscience, 2014 Retrieval of synaptic vesicles can occur 1-10 s after fusion, but the role of clathrin during this process has been unclear because the classical mode of clathrin-mediated endocytosis (CME) is an order of magnitude slower, as during retrieval of surface ...
Ilaria ePelassa +8 more
doaj +1 more source
The Ins and Outs of Antigen Uptake in B cells
Frontiers in Immunology, 2022 A review of our current knowledge of B cell antigen uptake mechanisms, the relevance of these processes to pathology, and outstanding questions in the field.
Adam Nathan McShane, Dessislava Malinova
doaj +1 more source
Transmission electron microscopy of a chc1 (clathrin) mutant in yeast
, 2012 Electron micrographs of chc1 (clathrin heavy chain) mutant yeast cells.
Ethan Perlstein (97610) +1 more
core +1 more source
Conformation Switching of Clathrin Light Chain Regulates Clathrin Lattice Assembly [PDF]
, 2010 SummaryClathrin-coated vesicle formation is responsible for membrane traffic to and from the endocytic pathway during receptor-mediated endocytosis and organelle biogenesis, influencing how cells relate to their environment.
Wilbur, Jeremy D. +7 more
core +1 more source
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
Advanced Functional Materials, EarlyView.A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Clathrin facilitates the morphogenesis of retrovirus particles.
PLoS Pathogens, 2011 The morphogenesis of retroviral particles is driven by Gag and GagPol proteins that provide the major structural component and enzymatic activities required for particle assembly and maturation.
Fengwen Zhang +4 more
doaj +1 more source
Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells
Frontiers in Microbiology, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Mei Li +18 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Clathrin-Independent Pathways of Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 There are many pathways of endocytosis at the cell surface that apparently operate at the same time. With the advent of new molecular genetic and imaging tools, an understanding of the different ways by which a cell may endocytose cargo is increasing by leaps and bounds.
Mayor, Satyajit +2 more
openaire +5 more sources