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Dynamin Rings: Not Just for Fission
The GTPase dynamin has captivated researchers for over two decades, even managing to establish its own research field. Dynamin's allure is partly due to its unusual biochemical properties as well as its essential role in multiple cellular processes, which include the regulation of clathrin‐mediated endocytosis and of actin cytoskeleton. On the basis of
Sever, Sanja, Chang, Joann, Gu, Changkyu
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SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity.
Dynamin I is a highly regulated GTPase enzyme enriched in nerve terminals which mediates vesicle fission during synaptic vesicle endocytosis. One regulatory mechanism involves its interactions with proteins containing Src homology 3 (SH3) domains.
Sai Krishnan +2 more
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A feedback loop between dynamin and actin recruitment during clathrin-mediated endocytosis.
Clathrin-mediated endocytosis proceeds by a sequential series of reactions catalyzed by discrete sets of protein machinery. The final reaction in clathrin-mediated endocytosis is membrane scission, which is mediated by the large guanosine triophosphate ...
Marcus J Taylor +2 more
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Bovine respiratory syncytial virus (BRSV) is an RNA virus with envelope that causes acute, febrile, and highly infectious respiratory diseases in cattle. However, the manner and mechanism of BRSV entry into cells remain unclear.
Yang Liu +6 more
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Bacterial dynamin homolog regulates growth phase-dependent c-di-GMP production
The bacterial second messenger bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) governs the transition from motile to sessile lifestyle by suppressing flagellar motility and promoting the synthesis of the extracellular biofilm matrix.
Xuanlin Chen +4 more
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alexae. Dynamine alexae Peñalver & Grimaldi, 2006 Nymphalidae: Biblidinae. Dominican Republic, Cordillera Septentrional between Santago and Puerto Plata, Dominican Amber; Aquitanian, early Miocene. Depository: AMNH (holotype, DR-18-2). Published figures: Peñalver & Grimaldi (2006: Figs 3–5).
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Role of the Host Membrane Trafficking Protein Dynamin 2 in Cell-to-Cell Spread of Bacterial Pathogens. [PDF]
Ireton K.
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Deployment of endocytic machinery to periactive zones of nerve terminals is independent of active zone assembly and evoked release. [PDF]
Emperador-Melero J +4 more
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Dynamic regulation of TASK-1 channels under cellular stress. [PDF]
Yu Y, Curry J, Tankersley S, Hu K.
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