Results 1 to 10 of about 28,974 (239)

SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity. [PDF]

PLoS ONE, 2015
Dynamin I is a highly regulated GTPase enzyme enriched in nerve terminals which mediates vesicle fission during synaptic vesicle endocytosis. One regulatory mechanism involves its interactions with proteins containing Src homology 3 (SH3) domains.
Sai Krishnan, Michael Collett, Phillip J Robinson   +2 more
doaj   +2 more sources

Role of the Host Membrane Trafficking Protein Dynamin 2 in Cell-to-Cell Spread of Bacterial Pathogens [PDF]

Cells
Although evolutionarily distant, the bacteria Listeria monocytogenes, Shigella flexneri, and Burkholderia thailandensis each undergo a “cell-to-cell” spreading process that allows these pathogens to disseminate within human tissues. Spread initiates when
Keith Ireton
doaj   +2 more sources

Dynamin-Like Protein B of Dictyostelium Contributes to Cytokinesis Cooperatively with Other Dynamins [PDF]

Cells, 2019
Dynamin is a large GTPase responsible for diverse cellular processes, such as endocytosis, division of organelles, and cytokinesis. The social amoebozoan, Dictyostelium discoideum, has five dynamin-like proteins: dymA, dymB, dlpA, dlpB, and dlpC.
Koushiro Fujimoto, Masahito Tanaka, A.Y. K. Md. Masud Rana, Md. Golam Sarowar Jahan, Go Itoh, Masatsune Tsujioka, Taro Q. P. Uyeda, Shin-ya Miyagishima, Shigehiko Yumura   +8 more
doaj   +3 more sources

Decapod iridescent virus 1 (DIV1) enters hematopoietic Cherax quadricarinatus cells via caveola-mediated endocytosis in a pH-dependent manner [PDF]

Journal of Virology
Decapod iridescent virus 1 (DIV1), the first isolated species of the genus Decapodiridovirus (family Iridoviridae), is a major pathogen threatening farmed decapods, causing large-scale disease outbreaks and high mortality.
Qin Zheng, Xiaojuan Chen, Furong Zhao, Junhao Zhang, Jianming Chen   +4 more
doaj   +2 more sources

Immunolocalization of Dynamin I Protein in Projection Neurons of the Visual System of the Adult Cat [PDF]

Journal of Experimental Neuroscience, 2009
We here report on the immunolocalization of Dynamin I (Dyn I) in neurons of the visual system of the cat. The lateral geniculate nucleus (LGN) complex displayed abundant Dyn I immunoreactivity in typical relay cells of the X-, Y- and W-pathway.
Lieselotte Cnops, Annemie Cuyvers, Tjing-Tjing Hu, Lutgarde Arckens   +3 more
doaj   +3 more sources

Confocal Microscopy Investigations of Biopolymeric PLGA Nanoparticle Uptake in Arabidopsis thaliana L. Cultured Cells and Plantlet Roots

Plants, 2023
To date, most endocytosis studies in plant cells have focused on clathrin-dependent endocytosis, while limited evidence is available on clathrin-independent pathways.
Giulia De Angelis, Camilla Badiali, Laura Chronopoulou, Cleofe Palocci, Gabriella Pasqua   +4 more
doaj   +1 more source

The in Vivo Phosphorylation Sites of Rat Brain Dynamin I [PDF]

Journal of Biological Chemistry, 2007
Dynamin I (dynI) is phosphorylated in synaptosomes at Ser(774) and Ser(778) by cyclin-dependent kinase 5 to regulate recruitment of syndapin I for synaptic vesicle endocytosis, and in PC12 cells on Ser(857). Hierarchical phosphorylation of Ser(774) precedes phosphorylation of Ser(778).
Graham, Mark E., Anggono, Victor, Bache, Nicolai, Larsen, Martin R., Craft, George E., Robinson, Phillip J.   +5 more
openaire   +4 more sources

Inositol hexakisphosphate promotes dynamin I- mediated endocytosis [PDF]

Proceedings of the National Academy of Sciences, 2002
Membrane homeostasis is maintained by exocytosis and endocytosis. The molecular mechanisms regulating the interplay between these two processes are not clear. Inositol hexakisphosphate (InsP 6 ) is under metabolic control and serves as a signal in the pancreatic β cell stimulus-secretion ...
Marianne, Høy, Alexander M, Efanov, Alejandro M, Bertorello, Sergei V, Zaitsev, Hervør L, Olsen, Krister, Bokvist, Barbara, Leibiger, Ingo B, Leibiger, Jean, Zwiller, Per-Olof, Berggren, Jesper, Gromada   +10 more
openaire   +2 more sources

Dynamin inhibitor impairsToxoplasma gondiiinvasion [PDF]

FEMS Microbiology Letters, 2009
The protozoan parasite Toxoplasma gondii infects its host cells through an active mechanism. In this work, we obtained evidence that host cells also play a fundamental role during the infection process. We found that previous incubation of the host cells, but not the parasites, with Dynasore, a small molecule that inhibits dynamin GTPase activity ...
Lucio Ayres, Caldas, Márcia, Attias, Wanderley, de Souza   +2 more
openaire   +2 more sources

Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis [PDF]

Nature Neuroscience, 2006
Dynamin I is dephosphorylated at Ser-774 and Ser-778 during synaptic vesicle endocytosis (SVE) in nerve terminals. Phosphorylation was proposed to regulate the assembly of an endocytic protein complex with amphiphysin or endophilin. Instead, we found it recruits syndapin I for SVE and does not control amphiphysin or endophilin binding in rat ...
Anggono, V, Smillie, KJ, Graham, ME, Valova, VA, Cousin, MA, Robinson, PJ   +5 more
openaire   +7 more sources