Results 1 to 10 of about 50,252 (279)

SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity. [PDF]

PLoS ONE, 2015
Dynamin I is a highly regulated GTPase enzyme enriched in nerve terminals which mediates vesicle fission during synaptic vesicle endocytosis. One regulatory mechanism involves its interactions with proteins containing Src homology 3 (SH3) domains.
Sai Krishnan, Michael Collett, Phillip J Robinson   +2 more
doaj   +2 more sources

Decapod iridescent virus 1 (DIV1) enters hematopoietic Cherax quadricarinatus cells via caveola-mediated endocytosis in a pH-dependent manner [PDF]

Journal of Virology
Decapod iridescent virus 1 (DIV1), the first isolated species of the genus Decapodiridovirus (family Iridoviridae), is a major pathogen threatening farmed decapods, causing large-scale disease outbreaks and high mortality.
Qin Zheng, Xiaojuan Chen, Furong Zhao, Junhao Zhang, Jianming Chen   +4 more
doaj   +2 more sources

Confocal Microscopy Investigations of Biopolymeric PLGA Nanoparticle Uptake in Arabidopsis thaliana L. Cultured Cells and Plantlet Roots

Plants, 2023
To date, most endocytosis studies in plant cells have focused on clathrin-dependent endocytosis, while limited evidence is available on clathrin-independent pathways.
Giulia De Angelis, Camilla Badiali, Laura Chronopoulou, Cleofe Palocci, Gabriella Pasqua   +4 more
doaj   +1 more source

The yeast dynamin-like GTPase Vps1 mediates Atg9 transport to the phagophore assembly site in Saccharomyces cerevisiae

Autophagy Reports, 2023
Macroautophagy/autophagy is a degradative pathway that plays an important role in maintaining cellular homeostasis in eukaryotes. During autophagy, cisternal compartments called phagophores are generated to sequester intracellular components; these ...
Yan Hu, Fulvio Reggiori
doaj   +1 more source

Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways

Microorganisms, 2022
Peptidoglycan (PGN), a polymeric glycan macromolecule, is a major constituent of the bacterial cell wall and a conserved pathogen-associated molecular pattern (PAMP) that triggers immune responses through cytosolic sensors.
Narcis I. Popescu, Jackie Cochran, Elizabeth Duggan, Jędrzej Kluza, Robert Silasi, Kenneth Mark Coggeshall   +5 more
doaj   +1 more source

Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. [PDF]

PLoS ONE, 2013
Heart failure due to diastolic dysfunction exacts a major economic, morbidity and mortality burden in the United States. Therapeutic agents to improve diastolic dysfunction are limited. It was recently found that Dynamin related protein 1 (Drp1) mediates
Danchen Gao, Li Zhang, Ranvir Dhillon, Ting-Ting Hong, Robin M Shaw, Jianhua Zhu   +5 more
doaj   +1 more source

Karenia brevis Extract Induces Cellular Entry through Distinct Mechanisms in Phagocytic RAW 264.7 Macrophages versus Non-Phagocytic Vero Cells

Marine Drugs, 2023
Marine algae extracts are an important area of potential drug discovery; however, nearly all studies to date have used non-fluorescent-based methods to determine changes in target cell activity. Many of the most robust immunological and cellular analyses
Laurie A. Minns, Kathryn T. Sausman, Ariel P. Brown, Robert A. York, Jennifer R. McCall   +4 more
doaj   +1 more source

The Relationship between Mutations in Gene-Specific Domains of Salivary Fibronectin (cFn) and Dynamin-2 (Dynm-2) and the Development of Porphyromonas gingivalis-Initiated Periodontitis

Journal of Molecular Pathology, 2022
Periodontitis is a chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. Its high prevalence and negative effects on quality of life make it one of the current problems in dentistry.
Elena A. Oleinik, Anna V. Goncharenko
doaj   +1 more source

Bezafibrate Improves Mitochondrial Fission and Function in DNM1L-Deficient Patient Cells

Cells, 2020
Mitochondria are involved in many cellular processes and their main role is cellular energy production. They constantly undergo fission and fusion, and these counteracting processes are under strict balance. The cytosolic dynamin-related protein 1, Drp1,
Liza Douiev, Ruth Sheffer, Gabriella Horvath, Ann Saada   +3 more
doaj   +1 more source

Regulatory Mechanism of Peroxisome Number Reduction Caused by FgPex4 and FgPex22-like Deletion in Fusarium graminearum

Journal of Fungi, 2023
Peroxisomes are single-membrane-bound organelles that play critical roles in eukaryotic cellular functions. Peroxisome quantity is a key factor influencing the homeostasis and pathogenic processes of pathogenic fungi.
Chunjie Liu, Zhuoyu Bi, Hao Xu, Renjie Zhang, Jiayi Wang, Yuancun Liang, Li Zhang, Jinfeng Yu   +7 more
doaj   +1 more source