Results 31 to 40 of about 50,252 (279)

Dynamin recruitment by clathrin coats: a physical step? [PDF]

, 2003
Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G., Fournier, J. -B., Galatola, P.   +2 more
core   +2 more sources

Two dynamin-like proteins stabilize FtsZ rings during Streptomyces sporulation [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Bacterial dynamins were discovered ∼10 y ago and the explosion in genome sequencing has shown that they radiate throughout the bacteria, being present in >1,000 species. In eukaryotes, dynamins play critical roles in the detachment of endocytic vesicles from the plasma membrane, the division of chloroplasts and peroxisomes ...
Susan Schlimpert, Sebastian Wasserstrom, Govind Chandra, Maureen J. Bibb, Kim C. Findlay, Klas Flärdh, Mark J. Buttner   +6 more
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Entacapone Treatment Modulates Hippocampal Proteins Related to Synaptic Vehicle Trafficking

Cells, 2020
Entacapone, a reversible inhibitor of catechol-O-methyl transferase, is used for patients in Parkinson’s disease because it increases the bioavailability and effectiveness of levodopa.
Dae Young Yoo, Hyo Young Jung, Woosuk Kim, Kyu Ri Hahn, Hyun Jung Kwon, Sung Min Nam, Jin Young Chung, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang   +9 more
doaj   +1 more source

Signal Recognition Particle (SRP) and SRP Receptor: A New Paradigm for Multistate Regulatory GTPases [PDF]

, 2009
The GTP-binding proteins or GTPases comprise a superfamily of proteins that provide molecular switches in numerous cellular processes. The “GTPase switch” paradigm, in which a GTPase acts as a bimodal switch that is turned “on” and “off” by external ...
Schmid, Sandra L., Shan, Shu-ou, Zhang, Xin   +2 more
core   +2 more sources

The in Vivo Phosphorylation Sites of Rat Brain Dynamin I

Journal of Biological Chemistry, 2007
Dynamin I (dynI) is phosphorylated in synaptosomes at Ser(774) and Ser(778) by cyclin-dependent kinase 5 to regulate recruitment of syndapin I for synaptic vesicle endocytosis, and in PC12 cells on Ser(857). Hierarchical phosphorylation of Ser(774) precedes phosphorylation of Ser(778).
Graham, Mark E., Anggono, Victor, Bache, Nicolai, Larsen, Martin R., Craft, George E., Robinson, Phillip J.   +5 more
openaire   +4 more sources

Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis

EMBO reports, 2023
AbstractMycobacterium tuberculosis (Mtb) secretes extracellular vesicles (EVs) containing a variety of proteins, lipoproteins, and lipoglycans. While emerging evidence suggests that EVs contribute to tuberculosis pathogenesis, the factors and molecular mechanisms involved in mycobacterial EV production have not been identified.
Shamba Gupta, Madhuri Bhagavathula, Vartika Sharma, Nishant Sharma, Nevadita Sharma, Ashis Biswas, Ainhoa Palacios, Vivian Salgueiro, Jose L Lavín, Navneet Dogra, Padmini Salgame, Rafael Prados‐Rosales, G Marcela Rodríguez   +12 more
openaire   +2 more sources

Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process [PDF]

, 2016
Under basal conditions the action potential firing rate of adrenal chromaffin cells is lower than 0.5 Hz. The maintenance of the secretory response at such frequencies requires a continuous replenishment of releasable vesicles.
Alvarez, Yanina Daniela, Bayonés, Lucas, Belingheri, Ana Verónica, Cárdenas, Ana M., González-Jamett, Arlek M., Marengo, Fernando Diego, Montenegro, Mauricio Norman, Moya Diaz, José Abelino   +7 more
core   +1 more source

Interactions of Phocein with Nucleoside-Diphosphate Kinase, Eps15, and Dynamin I [PDF]

Journal of Biological Chemistry, 2002
Phocein, an intracellular protein interacting with striatin, bears a few homologies with the sigma-subunits of clathrin adaptor proteins (Baillat, G., Moqrich, A., Castets, F., Baude, A., Bailly, Y., Benmerah, A., and Monneron, A. (2001) Mol. Biol. Cell 12, 663-673).
Gilbert, Baillat, Stephane, Gaillard, Francis, Castets, Ariane, Monneron   +3 more
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DNM1 encephalopathy: A new disease of vesicle fission. [PDF]

, 2017
ObjectiveTo evaluate the phenotypic spectrum caused by mutations in dynamin 1 (DNM1), encoding the presynaptic protein DNM1, and to investigate possible genotype-phenotype correlations and predicted functional consequences based on structural modeling ...
Campbell, Colleen A, Cervenka, Mackenzie C, Cilio, Maria R, Cohen, Julie S, Dlugos, Dennis J, Epi4K Consortium, EuroEPINOMICS-RES NLES Working Group, Fatemi, Ali, Helbig, Ingo, Helbig, Katherine L, Hernandez-Hernandez, Laura, Hollingsworth, Georgie, Huether, Robert, Joshi, Charuta N, Kaplan, Richard A, Kirsch, Heidi, Kolbe, Diana L, Lawson, John A, Littlejohn, Rebecca, Lourenço, Charles, Maher, Bridget, McClellan, Rebecca, McLean, Scott D, Muhle, Hiltrud, Møller, Rikke S, Neubauer, Bernd A, Nunes, Mark E, Palmer, Elizabeth, Pena, Sérgio DJ, Pendziwiat, Manuela, Sagawa, Yoshimi, Sarco, Dean P, Scheffer, Ingrid E, Shinde, Deepali N, Sisodiya, Sanjay M, Slavotinek, Anne, Stephani, Ulrich, von Spiczak, Sarah, Yuen, Amy   +38 more
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Mechanistic insights into mutually exclusive splicing in dynamin 1 [PDF]

Bioinformatics, 2013
Abstract Summary: Mutually exclusive splicing is a strictly regulated pattern of alternative splicing. A specific group of mutually exclusive splicing events has been shown to be regulated by the formation of specific RNA secondary structures. This type of regulation has been shown to exist only in arthropods.
openaire   +2 more sources