Results 21 to 30 of about 63,952 (280)
Monitoring of dynamin during the Toxoplasma gondii cell cycle [PDF]
, 2016 The obligate intracellular protozoan parasite Toxoplasma gondii actively invades virtually all warm-blooded nucleated cells. This process results in a non-fusogenic vacuole, inside which the parasites replicate continuously until egress signaling is ...
Attias, Marcia +4 more
core +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Viruses, 2023 Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) canonically utilizes clathrin-mediated endocytosis (CME) and several other endocytic mechanisms to invade airway epithelial cells. Endocytic inhibitors, particularly those targeting CME-related
Mohamed Hessien +11 more
doaj +1 more source
Phosphorylation of dynamin by ERK2 inhibits the dynamin‐microtubule interaction [PDF]
FEBS Letters, 1996 In the present study we show that purified bovine brain dynamin can be phosphorylated by MAP kinase, ERK2, with a stoichiometry of 1 mol phosphate/mol dynamin. The phosphorylated serine residue is located within the C‐terminal 10 kDa of dynamin. Dynamin I phosphorylated by ERK2 can be specifically dephosphorylated by calcineurin but not by protein ...
Earnest, Svetlana +3 more
openaire +2 more sources
Structure and function of bacterial dynamin-like proteins [PDF]
, 2012 Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core +1 more source
Effect of 4 Weeks of Moderate-Intensity Endurance Exercise and Lithium Administration on Blood Glucose Level in STZ-Induced Type 1 Diabetes Mellitus Mice [PDF]
운동과학, 2022 Purpose The purpose of this study was to investigate the effects of short-term endurance exercise and lithium treatment on fasting blood glucose in rats with type 1 diabetes (T1DM).
Su-Ryun Jung
doaj +1 more source
Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]
, 2007 The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY +7 more
core +2 more sources
Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking
Cells, 2022 Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It occurs via a variety of mechanisms and involves many regulatory proteins.
Chayanika Gundu +7 more
doaj +1 more source
Dynamin Subunit Interactions Revealed [PDF]
Developmental Cell, 2010 Dynamin family members are large GTPases that assemble into multimeric spirals. These spirals promote membrane fission or fusion, or they inhibit processes such as viral replication. Two new studies by Chappie et al. and Gao et al. in a recent issue of Nature identify interactions between subunits of dynamin spirals, advancing mechanistic understanding
van der Bliek, Alexander M. +1 more
openaire +2 more sources
Dynamin recruitment by clathrin coats: a physical step? [PDF]
, 2003 Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G. +2 more
core +2 more sources