Results 11 to 20 of about 41,917 (266)
Phosphorylation of dynamin by ERK2 inhibits the dynamin‐microtubule interaction [PDF]
FEBS Letters, 1996 In the present study we show that purified bovine brain dynamin can be phosphorylated by MAP kinase, ERK2, with a stoichiometry of 1 mol phosphate/mol dynamin. The phosphorylated serine residue is located within the C‐terminal 10 kDa of dynamin. Dynamin I phosphorylated by ERK2 can be specifically dephosphorylated by calcineurin but not by protein ...
Earnest, Svetlana +3 more
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Dynamin 1 is required for memory formation. [PDF]
PLoS ONE, 2014 Dynamin 1-3 isoforms are known to be involved in endocytotic processes occurring during synaptic transmission. No data has directly linked dynamins yet with normal animal behavior.
Mauro Fà +4 more
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SNARE Filtering by Dynamin [PDF]
Cell, 2004 Fission and fusion are the two elementary steps of membrane traffic. The mechanoenzyme dynamin acts at the fission step, but, in this issue of Cell, suggest an additional role of dynamin in preparing membranes for fusion.
Antonny, B., Antonny, Bruno
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Kalirin12 interacts with dynamin [PDF]
BMC Neuroscience, 2009 Abstract Background Guanine nucleotide exchange factors (GEFs) and their target Rho GTPases regulate cytoskeletal changes and membrane trafficking. Dynamin, a large force-generating GTPase, plays an essential role in membrane tubulation and fission in cells. Kalirin12, a neuronal RhoGEF, is found in growth cones early
Mains Richard E +3 more
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Dynamin Subunit Interactions Revealed [PDF]
Developmental Cell, 2010 Dynamin family members are large GTPases that assemble into multimeric spirals. These spirals promote membrane fission or fusion, or they inhibit processes such as viral replication. Two new studies by Chappie et al. and Gao et al. in a recent issue of Nature identify interactions between subunits of dynamin spirals, advancing mechanistic understanding
van der Bliek, Alexander M. +1 more
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Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms [PDF]
The Journal of Cell Biology, 1998 A role for dynamin in clathrin-mediated endocytosis is now well established. However, mammals express three closely related, tissue-specific dynamin isoforms, each with multiple splice variants. Thus, an important question is whether these isoforms and splice variants function in vesicle formation from distinct intracellular organelles.
Altschuler, Yoram +6 more
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A Corkscrew Model for Dynamin Constriction [PDF]
Structure, 2007 Numerous vesiculation processes throughout the eukaryotic cell are dependent on the protein dynamin, a large GTPase that constricts lipid bilayers. We have combined X-ray crystallography and cryo-electron microscopy (cryo-EM) data to generate a coherent model of dynamin-mediated membrane constriction.
Mears, Jason A. +2 more
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Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin [PDF]
Journal of Cell Science, 2018 ABSTRACT mTORC1 plays a crucial role in protein synthesis and cell proliferation and growth. It is activated by growth factors and amino acids, including essential amino acids (EAAs), such as leucine; Leu enters cells via the Leu transporter LAT1–4F2hc (also known as SLC7A5–SLC3A2) and potentially via endocytosis.
Avinash Persaud +3 more
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Frontiers in Cell and Developmental Biology, 2022 Tilapia Lake Virus (TiLV) is an emerging virus lethal to tilapia, which threatens the global tilapia aquaculture with severe implications for food security.
Reem Abu Rass +5 more
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Journal of Cell Science, 2009 The superfamily of dynamins includes classical dynamins and dynamin-related proteins. Classical dynamins are proteins that share sequence similarity with the first described dynamin, which is a large GTPase with five characteristic domains.
Jürgen A W, Heymann, Jenny E, Hinshaw
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