Results 11 to 20 of about 4,246 (265)

Arabidopsis Dynamin-Related Protein AtDRP2A Contributes to Late Flg22-Signaling and Effective Immunity Against Pseudomonas syringae Bacteria

open access: yesMolecular Plant-Microbe Interactions, 2023
In eukaryotes, dynamins and dynamin-related proteins (DRPs) are high–molecular weight GTPases responsible for mechanochemical fission of organelles or membranes.
Gayani Ekanayake   +3 more
doaj   +1 more source

Cardiolipin targets a dynamin-related protein to the nuclear membrane

open access: yeseLife, 2021
Dynamins are targeted to specific cellular membranes that they remodel via membrane fusion or fission. The molecular basis of conferring specificity to dynamins for their target membrane selection is not known.
Usha Pallabi Kar   +2 more
doaj   +1 more source

The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3. [PDF]

open access: yesJ Neurosci
Hanke-Gogokhia C   +7 more
europepmc   +2 more sources

Changes of different connexins and mitochondrial dynamins in early acute kidney injury after liver transplantation [PDF]

open access: yesXin yixue, 2023
Objective To explore the potential relationship between different connexins and mitochondrial dynamic imbalance and mitochondrial injury in early acute kidney injury after liver transplantation.
Mai Kangfeng, Li Jiaai, Wei Jingru, Chen Chaojin, Li Xiaoyun
doaj   +1 more source

Role of GTPase-Dependent Mitochondrial Dynamins in Heart Diseases

open access: yesFrontiers in Cardiovascular Medicine, 2021
Heart function maintenance requires a large amount of energy, which is supplied by the mitochondria. In addition to providing energy to cardiomyocytes, mitochondria also play an important role in maintaining cell function and homeostasis.
Jiangen Liu   +3 more
doaj   +1 more source

Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1. [PDF]

open access: yesPLoS ONE, 2014
Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves translocation from the cytosol to the mitochondrial ...
Itsasne Bustillo-Zabalbeitia   +5 more
doaj   +1 more source

Dynamin and Cytokinesis [PDF]

open access: yesTraffic, 2006
Animal and plant cytokineses appear morphologically distinct. Recent studies, however, have revealed that these cellular processes have many things in common, including the requirement of co‐ordinated membrane trafficking and cytoskeletal dynamics. At the intersection of these two processes are the members of the dynamin family of ubiquitous eukaryotic
Catherine A, Konopka   +3 more
openaire   +2 more sources

Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer’s disease synapse model

open access: yeseLife, 2022
Elevation of soluble wild-type (WT) tau occurs in synaptic compartments in Alzheimer’s disease. We addressed whether tau elevation affects synaptic transmission at the calyx of Held in slices from mice brainstem. Whole-cell loading of WT human tau (h-tau)
Tetsuya Hori   +9 more
doaj   +1 more source

The dynamin superfamily [PDF]

open access: yesCurrent Biology, 2018
The dynamin superfamily comprises a growing assortment of multi-domain GTPases, found from bacteria to man, that are distinguished from typical GTPases of the Ras, Rab and G-protein families by their modular structure (Figure 1), relatively large size (>70 kDa), and low affinity for guanine nucleotides.
Rajesh, Ramachandran, Sandra L, Schmid
openaire   +2 more sources

A highly-sensitive high throughput assay for dynamin's basal GTPase activity. [PDF]

open access: yesPLoS ONE, 2017
Clathrin-mediated endocytosis is the major pathway by which cells internalize materials from the external environment. Dynamin, a large multidomain GTPase, is a key regulator of clathrin-mediated endocytosis.
Aparna Mohanakrishnan   +5 more
doaj   +1 more source

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