Results 11 to 20 of about 4,246 (265)
In eukaryotes, dynamins and dynamin-related proteins (DRPs) are high–molecular weight GTPases responsible for mechanochemical fission of organelles or membranes.
Gayani Ekanayake +3 more
doaj +1 more source
Cardiolipin targets a dynamin-related protein to the nuclear membrane
Dynamins are targeted to specific cellular membranes that they remodel via membrane fusion or fission. The molecular basis of conferring specificity to dynamins for their target membrane selection is not known.
Usha Pallabi Kar +2 more
doaj +1 more source
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3. [PDF]
Hanke-Gogokhia C +7 more
europepmc +2 more sources
Changes of different connexins and mitochondrial dynamins in early acute kidney injury after liver transplantation [PDF]
Objective To explore the potential relationship between different connexins and mitochondrial dynamic imbalance and mitochondrial injury in early acute kidney injury after liver transplantation.
Mai Kangfeng, Li Jiaai, Wei Jingru, Chen Chaojin, Li Xiaoyun
doaj +1 more source
Role of GTPase-Dependent Mitochondrial Dynamins in Heart Diseases
Heart function maintenance requires a large amount of energy, which is supplied by the mitochondria. In addition to providing energy to cardiomyocytes, mitochondria also play an important role in maintaining cell function and homeostasis.
Jiangen Liu +3 more
doaj +1 more source
Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1. [PDF]
Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves translocation from the cytosol to the mitochondrial ...
Itsasne Bustillo-Zabalbeitia +5 more
doaj +1 more source
Animal and plant cytokineses appear morphologically distinct. Recent studies, however, have revealed that these cellular processes have many things in common, including the requirement of co‐ordinated membrane trafficking and cytoskeletal dynamics. At the intersection of these two processes are the members of the dynamin family of ubiquitous eukaryotic
Catherine A, Konopka +3 more
openaire +2 more sources
Elevation of soluble wild-type (WT) tau occurs in synaptic compartments in Alzheimer’s disease. We addressed whether tau elevation affects synaptic transmission at the calyx of Held in slices from mice brainstem. Whole-cell loading of WT human tau (h-tau)
Tetsuya Hori +9 more
doaj +1 more source
The dynamin superfamily comprises a growing assortment of multi-domain GTPases, found from bacteria to man, that are distinguished from typical GTPases of the Ras, Rab and G-protein families by their modular structure (Figure 1), relatively large size (>70 kDa), and low affinity for guanine nucleotides.
Rajesh, Ramachandran, Sandra L, Schmid
openaire +2 more sources
A highly-sensitive high throughput assay for dynamin's basal GTPase activity. [PDF]
Clathrin-mediated endocytosis is the major pathway by which cells internalize materials from the external environment. Dynamin, a large multidomain GTPase, is a key regulator of clathrin-mediated endocytosis.
Aparna Mohanakrishnan +5 more
doaj +1 more source

