Results 31 to 40 of about 3,215 (217)

MoDnm1 Dynamin Mediating Peroxisomal and Mitochondrial Fission in Complex with MoFis1 and MoMdv1 Is Important for Development of Functional Appressorium in Magnaporthe oryzae. [PDF]

open access: yesPLoS Pathogens, 2016
Dynamins are large superfamily GTPase proteins that are involved in various cellular processes including budding of transport vesicles, division of organelles, cytokinesis, and pathogen resistance.
Kaili Zhong   +7 more
doaj   +1 more source

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei

open access: yesMicrobial Cell, 2016
The dynamins represent a superfamily of proteins that have been shown to function in a wide range of membrane fusion and fission events. An increasing number of mutations in the human classical dynamins, Dyn-1 and Dyn-2 has been reported, with diseases ...
Laila Moustaq   +4 more
doaj   +1 more source

Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation

open access: yeseLife, 2022
The formation of a clathrin-coated vesicle (CCV) is a major membrane remodeling process that is crucial for membrane traffic in cells. Besides clathrin, these vesicles contain at least 100 different proteins although it is unclear how many are essential ...
Cansu Küey   +4 more
doaj   +1 more source

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.

open access: yesPLoS ONE, 2017
Prion diseases are neurodegenerative conditions characterized by the conformational conversion of the cellular prion protein (PrPC), an endogenous membrane glycoprotein of uncertain function, into PrPSc, a pathological isoform that replicates by imposing
Claudia Stincardini   +16 more
doaj   +1 more source

Defective membrane remodeling in neuromuscular diseases: insights from animal models. [PDF]

open access: yesPLoS Genetics, 2012
Proteins involved in membrane remodeling play an essential role in a plethora of cell functions including endocytosis and intracellular transport. Defects in several of them lead to human diseases.
Belinda S Cowling   +3 more
doaj   +1 more source

Syntaphilin Binds to Dynamin-1 and Inhibits Dynamin-dependent Endocytosis [PDF]

open access: yesJournal of Biological Chemistry, 2003
Syntaphilin is a brain-specific syntaxin-binding partner first characterized as an inhibitor of SNARE complex formation and neurotransmitter release. Here we show that syntaphilin also binds to dynamin-1 and through this interaction inhibits dynamin-mediated endocytosis. Immunoprecipitation studies from cross-linked rat synaptosomes demonstrate that an
Sunit, Das   +2 more
openaire   +2 more sources

F-actin Bundle Sedimentation Assay

open access: yesBio-Protocol, 2019
Understanding the molecular mechanism governing the higher-order regulation of actin dynamics requires chemically-defined and quantitative assays. Recently, the membrane remodeling large GTPase, dynamin, has been identified as a new actin cross-linking ...
Shan-Shan Lin   +2 more
doaj   +1 more source

Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms [PDF]

open access: yesThe Journal of Cell Biology, 1998
A role for dynamin in clathrin-mediated endocytosis is now well established. However, mammals express three closely related, tissue-specific dynamin isoforms, each with multiple splice variants. Thus, an important question is whether these isoforms and splice variants function in vesicle formation from distinct intracellular organelles.
Altschuler, Yoram   +6 more
openaire   +4 more sources

Platelet granule exocytosis: A comparison with chromaffin cells

open access: yesFrontiers in Endocrinology, 2013
The rapid secretion of bioactive amines from chromaffin cells constitutes an important component of the fight or flight response of mammals to stress.
Jennifer eFitch-Tewfik   +1 more
doaj   +1 more source

A proteomic study of memory after imprinting in the domestic chick

open access: yesFrontiers in Behavioral Neuroscience, 2015
The intermediate and medial mesopallium (IMM) of the domestic chick forebrain has previously been shown to be a memory system for visual imprinting. Learning-related changes occur in certain plasma membrane and mitochondrial proteins in the IMM.
Maia eMeparishvili   +6 more
doaj   +1 more source

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