Results 31 to 40 of about 170,782 (263)
Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. [PDF]
PLoS Biology, 2016 Deficiency of the protein Wolfram syndrome 1 (WFS1) is associated with multiple neurological and psychiatric abnormalities similar to those observed in pathologies showing alterations in mitochondrial dynamics.
Michal Cagalinec +12 more
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Mitochondrial Dynamics in Pulmonary Hypertension
Biomedicines, 2023 Mitochondria are essential organelles for energy production, calcium homeostasis, redox signaling, and other cellular responses involved in pulmonary vascular biology and disease processes. Mitochondrial homeostasis depends on a balance in mitochondrial fusion and fission (dynamics).
Ed Wilson Santos +4 more
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Research in Cardiovascular Medicine, 2018 Mitochondria as dynamic organelle constantly undergo fusion and fission reactions, leading to continuous reconstruction of the mitochondrial network for elongated or fragmentation shapes and ultimately the mitophagy.
Babak Ebadi +4 more
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Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model. [PDF]
PLoS ONE, 2013 Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders.
Guo Luo +6 more
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Unveiling the potential of mitochondrial dynamics as a therapeutic strategy for acute kidney injury
Frontiers in Cell and Developmental Biology, 2023 Acute Kidney Injury (AKI), a critical clinical syndrome, has been strongly linked to mitochondrial malfunction. Mitochondria, vital cellular organelles, play a key role in regulating cellular energy metabolism and ensuring cell survival.
Yajie Hao +4 more
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006 Higher plant mitochondria are dynamic, pleomorphic organelles. The higher plant chondriome (all mitochondria in a cell collectively) is typically composed of numerous, physically discrete, mitochondria. However, frequent inter-mitochondrial fusion, enabling the mixing and recombination of mtDNA, ensures that the higher plant chondriome functions, at ...
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Mitochondrial dynamics and neurodegeneration [PDF]
Current Neurology and Neuroscience Reports, 2009 Mitochondria are key organelles in eukaryotic cells that not only generate adenosine triphosphate but also perform such critical functions as hosting essential biosynthetic pathways, calcium buffering, and apoptotic signaling. In vivo, mitochondria form dynamic networks that undergo frequent morphologic changes through fission and fusion.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior +11 more
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Scientific ReportsSelective degradation of dysfunctional or excess mitochondria is a fundamental process crucial for cell homeostasis in almost all eukaryotes. This process relies on autophagy, an intracellular self-eating system conserved from yeast to humans and is thus
Yuan Tian, Koji Okamoto
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New therapeutic directions in type II diabetes and its complications: mitochondrial dynamics
Frontiers in Endocrinology, 2023 As important organelles of energetic and metabolism, changes in the dynamic state of mitochondria affect the homeostasis of cellular metabolism. Mitochondrial dynamics include mitochondrial fusion and mitochondrial fission.
Shengnan Wang +7 more
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