Results 11 to 20 of about 3,715,868 (307)

Mitochondrial Dynamics in Mitochondrial Diseases

open access: yesDiseases, 2016
Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial ...
Juan M. Suárez-Rivero   +9 more
doaj   +4 more sources

Inhibition of Mitochondrial Dynamics by Mitochondrial Division Inhibitor-1 Suppresses Cell Migration and Metastatic Markers in Colorectal Cancer HCT116 Cells [PDF]

open access: yesJournal of Experimental Pharmacology
Tahir Mehmood,1,2 Qandeel Nasir,2 Iqra Younis,2 Chatchai Muanprasat1 1Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangpla, Bangplee, Samut Prakarn, Thailand; 2Department of Biological Sciences ...
Mehmood T   +3 more
doaj   +1 more source

Players in Mitochondrial Dynamics and Female Reproduction

open access: yesFrontiers in Molecular Biosciences, 2021
Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and mitochondrial quality control.
Weiwei Zou   +12 more
doaj   +1 more source

Correcting abnormal mitochondrial dynamics to facilitate tumor treatment

open access: yesMitochondrial Communications, 2023
Mitochondrial dynamics are closely related to various cellular physiological activities, including cell proliferation, homeostasis, and cell migration, and are regulated by a variety of enzymes, proteins and cytokines.
Bowen Yang, Yumeng Lin, Ying-Qiang Shen
doaj   +1 more source

Mitochondrial dynamics in neurodegeneration [PDF]

open access: yesTrends in Cell Biology, 2013
It has been only 15 years since studies began on the molecular mechanisms underlying mitochondrial fission and fusion using simple model organisms such as Drosophila, yeast, and Caenorhabditis elegans. Beyond the primary functions of mitochondrial fission and fusion in controlling organelle shape, size, and number, it became clear that these dynamic ...
Itoh, Kie   +3 more
openaire   +5 more sources

Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer

open access: yesJournal of Translational Medicine, 2023
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu   +7 more
doaj   +1 more source

Sphingolipids and Mitochondrial Dynamic [PDF]

open access: yesCells, 2020
For decades, sphingolipids have been related to several biological functions such as immune system regulation, cell survival, and proliferation. Recently, it has been reported that sphingolipids could be biomarkers in cancer and in other human disorders such as metabolic diseases.
Lais Brigliadori Fugio   +2 more
openaire   +3 more sources

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

open access: yesMembranes, 2022
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi   +2 more
doaj   +1 more source

Mitochondrial dynamics and apoptosis [PDF]

open access: yesGenes & Development, 2008
In healthy cells, mitochondria continually divide and fuse to form a dynamic interconnecting network. The molecular machinery that mediates this organelle fission and fusion is necessary to maintain mitochondrial integrity, perhaps by facilitating DNA or protein quality control.
Der-Fen, Suen   +2 more
openaire   +2 more sources

Effects of fission and mitophagy on mitochondrial functionality under accelerated damage conditions: A mathematical modeling approach

open access: yesFrontiers in Applied Mathematics and Statistics, 2023
There is growing evidence that mitochondrial dynamics play a role in mitochondrial function quality control. Recent studies have discovered that physical activity can aid in maintaining a healthy mitochondrial population and may even counteract the ...
Ángel J. Zamora-Ramírez   +1 more
doaj   +1 more source

Home - About - Disclaimer - Privacy