Results 11 to 20 of about 184,138 (308)
Mitochondrial Dynamics in Mitochondrial Diseases
Diseases, 2016 Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial ...
Juan M. Suárez-Rivero +9 more
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Mitochondrial dynamics and mitochondrial quality control
Redox Biology, 2015 Mitochondria are cellular energy powerhouses that play important roles in maintaining cell survival, cell death and cellular metabolic homeostasis. Timely removal of damaged mitochondria via autophagy (mitophagy) is thus critical for cellular homeostasis
Hong-Min Ni +2 more
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Journal of Experimental PharmacologyTahir Mehmood,1,2 Qandeel Nasir,2 Iqra Younis,2 Chatchai Muanprasat1 1Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangpla, Bangplee, Samut Prakarn, Thailand; 2Department of Biological Sciences ...
Mehmood T +3 more
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Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection
Biochimica Et Biophysica Acta - Bioenergetics, 2017 Mitochondrial dysfunction is a hallmark of many diseases. The retrograde signaling initiated by dysfunctional mitochondria can bring about global changes in gene expression that alters cell morphology and function. Typically, this is attributed to disruption of important mitochondrial functions, such as ATP production, integration of metabolism ...
Satish Srinivasan +2 more
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Mitochondrial dynamics and cancer
Seminars in Cancer Biology, 2009 Mitochondrial morphology is regulated by continuous fusion and fission events that are essential for maintaining a normal mitochondrial function. If the last years have witnessed major discoveries in the characterization of the fission and fusion machineries, little is known about the physiological role of mitochondrial dynamics.
Grandemange, Stéphanie +2 more
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Players in Mitochondrial Dynamics and Female Reproduction
Frontiers in Molecular Biosciences, 2021 Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and mitochondrial quality control.
Weiwei Zou +12 more
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Correcting abnormal mitochondrial dynamics to facilitate tumor treatment
Mitochondrial Communications, 2023 Mitochondrial dynamics are closely related to various cellular physiological activities, including cell proliferation, homeostasis, and cell migration, and are regulated by a variety of enzymes, proteins and cytokines.
Bowen Yang, Yumeng Lin, Ying-Qiang Shen
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Mitochondrial dynamics and apoptosis [PDF]
Genes & Development, 2008 In healthy cells, mitochondria continually divide and fuse to form a dynamic interconnecting network. The molecular machinery that mediates this organelle fission and fusion is necessary to maintain mitochondrial integrity, perhaps by facilitating DNA or protein quality control.
Der-Fen, Suen +2 more
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Journal of Translational Medicine, 2023 Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu +7 more
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Mitochondrial dynamics in neurodegeneration [PDF]
Trends in Cell Biology, 2013 It has been only 15 years since studies began on the molecular mechanisms underlying mitochondrial fission and fusion using simple model organisms such as Drosophila, yeast, and Caenorhabditis elegans. Beyond the primary functions of mitochondrial fission and fusion in controlling organelle shape, size, and number, it became clear that these dynamic ...
Itoh, Kie +3 more
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