Results 21 to 30 of about 3,715,868 (307)
Disturbance of Mitochondrial Dynamics and Mitochondrial Therapies in Atherosclerosis [PDF]
Life, 2021 Mitochondrial dysfunction is associated with a wide range of chronic human disorders, including atherosclerosis and diabetes mellitus. Mitochondria are dynamic organelles that undergo constant turnover in living cells. Through the processes of mitochondrial fission and fusion, a functional population of mitochondria is maintained, that responds to the ...
Alexander M. Markin +7 more
openaire +3 more sources
Mitochondrial Dynamics in Diabetes [PDF]
Antioxidants & Redox Signaling, 2011 Mitochondria are at the center of cellular energy metabolism and regulate cell life and death. The cell biological aspect of mitochondria, especially mitochondrial dynamics, has drawn much attention through implications in human pathology, including neurological disorders and metabolic diseases. Mitochondrial fission and fusion are
Yisang, Yoon +3 more
openaire +2 more sources
Mitochondrial dynamics and cancer [PDF]
Tumor Biology, 2017 Cancer is among the leading causes of death worldwide, and the number of new cases continues to rise. Despite recent advances in diagnosis and therapeutic strategies, millions of cancer-related deaths occur, indicating the need for better therapies and diagnostic strategies.
Paola Maycotte +5 more
openaire +3 more sources
The control of mitochondrial morphology and dynamics in Arabidopis thaliana [PDF]
, 2012 Mitochondria are ubiquitous eukaryotic organelles which carry out a range of essential functions, most notably the production of ATP through the process of oxidative phosphorylation.
Scott, Iain
core +2 more sources
Frontiers in Cell and Developmental Biology, 2020 Cardiac ischemia-reperfusion (I/R) injury is associated with mitochondrial dysfunction. Recent studies have reported that mitochondrial function is determined by mitochondrial dynamics.
Yuanyan Deng +5 more
doaj +1 more source
Frontiers in Neuroscience, 2021 In neurodegenerative diseases, neurodegeneration has been related to several mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria, impaired mitophagy, and blocked mitochondria mitochondrial transport in axons.
Danying Yang +16 more
doaj +1 more source
Emergence of the mitochondrial reticulum from fission and fusion dynamics [PDF]
, 2012 Mitochondria form a dynamic tubular reticulum within eukaryotic cells. Currently, quantitative understanding of its morphological characteristics is largely absent, despite major progress in deciphering the molecular fission and fusion machineries ...
Michael Meyer-Hermann +13 more
core +1 more source
Impacts of impaired mitochondrial dynamics in hearing loss: Potential therapeutic targets
Frontiers in Neuroscience, 2022 Mitochondria are the powerhouse of the cells. Under physiological conditions, mitochondrial fission and fusion maintain a dynamic equilibrium in the cytoplasm, which is referred to as mitochondrial dynamics.
Tianyuan Zou +29 more
doaj +1 more source
Mitochondrial dynamics in astrocytes [PDF]
Biochemical Society Transactions, 2014 Astrocytes exhibit cellular excitability through variations in their intracellular calcium (Ca2+) levels in response to synaptic activity. Astrocyte Ca2+ elevations can trigger the release of neuroactive substances that can modulate synaptic transmission and plasticity, hence promoting bidirectional communication with neurons.
Stephen, TL +2 more
openaire +3 more sources
Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem Cells
Frontiers in Cell and Developmental Biology, 2020 Mesenchymal stem cells (MSCs) are pivotal to tissue homeostasis, repair, and regeneration due to their potential for self-renewal, multilineage differentiation, and immune modulation.
Lin Ren +17 more
doaj +1 more source