Results 51 to 60 of about 2,483,935 (295)

Coordinated Translocation of Presequence-Containing Precursor Proteins Across Two Mitochondrial Membranes: Knowns and Unknowns of How TOM and TIM23 Complexes Cooperate With Each Other

Frontiers in Physiology, 2022
The vast majority of mitochondrial proteins are encoded in the nuclear genome and synthesized on cytosolic ribosomes as precursor proteins with specific mitochondrial targeting signals. Mitochondrial targeting signals are very diverse, however, about 70%
Marcel G. Genge, Dejana Mokranjac
doaj   +1 more source

A mitochondrial import receptor for the ADP/ATP carrier [PDF]

, 1990
We have identified a mitochondrial outer membrane protein of 72 kd (MOM72) that exhibits the properties of an import receptor for the ADP/ATP carrier (AAC), the most abundant mitochondrial protein.
Söllner, Thomas, Pfanner, Nikolaus, Pfaller, Rupert, Neupert, Walter, Griffiths, Gareth   +4 more
core   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert, Pfanner, Nikolaus, Steger, Heinrich F., Rassow, Joachim, Neupert, Walter   +4 more
core   +1 more source

Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain

Frontiers in Cell and Developmental Biology, 2022
Mitochondria are complex organelles containing 13 proteins encoded by mitochondrial DNA and over 1,000 proteins encoded on nuclear DNA. Many mitochondrial proteins are associated with the inner or outer mitochondrial membranes, either peripherally or as ...
David R. L. Robinson, Daniella H. Hock, Linden Muellner-Wong, Linden Muellner-Wong, Roopasingam Kugapreethan, Boris Reljic, Boris Reljic, Elliot E. Surgenor, Elliot E. Surgenor, Carlos H. M. Rodrigues, Carlos H. M. Rodrigues, Nikeisha J. Caruana, Nikeisha J. Caruana, David A. Stroud, David A. Stroud   +14 more
doaj   +1 more source

Comparative Analysis of Methodological Aspects of the Study of Extracellular Vesicles and Extracellular Mitochondria: From Isolation to Internalization

Current Issues in Molecular Biology
Mitochondrial transfer in mammals has been proven to occur both under physiological conditions and during pathological conditions. It has been shown that neighboring cells can exchange mitochondria via nanotunnel tubes.
Natalia Yunusova, Dmitry Svarovsky, Evgenya Kaigorodova, Alexey Dobrodeev, Virab Sisakian, Svetlana Tamkovich   +5 more
doaj   +1 more source

Players in Mitochondrial Dynamics and Female Reproduction

Frontiers in Molecular Biosciences, 2021
Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and mitochondrial quality control.
Weiwei Zou, Weiwei Zou, Weiwei Zou, Dongmei Ji, Dongmei Ji, Dongmei Ji, Zhiguo Zhang, Zhiguo Zhang, Zhiguo Zhang, Li Yang, Yunxia Cao, Yunxia Cao, Yunxia Cao   +12 more
doaj   +1 more source

The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid. [PDF]

, 2013
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core ...
George Desmond Clark-Walker (281878), George Desmond Clark-Walker, Dosztányi Zsuzsanna, Zsuzsanna Dosztányi (57464), Clark-Walker, George Desmond, Zsuzsanna Dosztányi, Clark-Walker George Desmond, David C. Hayward (198611), David C. Hayward, Hayward David C., Hayward, David C., Dosztányi, Zsuzsanna, David C Hayward   +12 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exploratory analysis of mitochondrial transcription factor A as a putative biomarker for osteoporosis: a cross-sectional study

Frontiers in Endocrinology
BackgroundNumerous studies have linked mitochondrial dysfunction to osteoporosis; however, the roles of mitochondrial transcription factor A (TFAM) and oxidative stress in osteoporosis are unclear.
Yinyin Zhang, Guoying Wu, Jialu Hou, Qipei Liu, Zehua Guo, Yukai Zhang, Ying Li   +6 more
doaj   +1 more source

Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein interaction network. [PDF]

PLoS ONE, 2011
Mitochondria are major players on the production of energy, and host several key reactions involved in basic metabolism and biosynthesis of essential molecules.
Jian Cui, Jinghua Liu, Yuhua Li, Tieliu Shi   +3 more
doaj   +1 more source