Results 51 to 60 of about 910,991 (300)

Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy [PDF]

, 2019
The mosaic distribution of cytochrome c oxidase(+) (COX+) and COX - muscle fibers in mitochondrial disorders allows the sampling of fibers with compensated and decompensated mitochondrial function from the same individual.
Doll, S., Geyer, P., Klopstock, T., Mann, M., Murgia, M., Tan, J.   +5 more
core   +3 more sources

Mitochondrial Protein Homeostasis and Cardiomyopathy

International Journal of Molecular Sciences, 2022
Human mitochondrial disorders impact tissues with high energetic demands and can be associated with cardiac muscle disease (cardiomyopathy) and early mortality. However, the mechanistic link between mitochondrial disease and the development of cardiomyopathy is frequently unclear.
Emily Wachoski-Dark, Tian Zhao, Aneal Khan, Timothy E. Shutt, Steven C. Greenway   +4 more
openaire   +2 more sources

Biochemical and Proteomic Analyses in Drought-Tolerant Wheat Mutants Obtained by Gamma Irradiation

Plants
The bread wheat cultivar (Triticum aestivum L. cv. Sagittario) as a parental line and its mutant, drought-tolerant lines (Mutant lines 4 and 5) were subjected to polyethylene glycol (PEG)-induced drought.
Ayşe Şen, Tamer Gümüş, Aslıhan Temel, İrfan Öztürk, Özge Çelik   +4 more
doaj   +1 more source

Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein interaction network. [PDF]

PLoS ONE, 2011
Mitochondria are major players on the production of energy, and host several key reactions involved in basic metabolism and biosynthesis of essential molecules.
Jian Cui, Jinghua Liu, Yuhua Li, Tieliu Shi   +3 more
doaj   +1 more source

The PINK1/Parkin pathway: a mitochondrial quality control system? [PDF]

, 2009
Significant insight into the mechanisms that contribute to dopaminergic neurodegeneration in Parkinson disease has been gained from the analysis of genes linked to rare heritable forms of parkinsonism such as PINK1 and parkin, loss-of-function mutations ...
Pallanck, L.J., Whitworth, A.J.
core   +1 more source

Sorting pathways of mitochondrial inner membrane proteins [PDF]

, 1990
Two distinct pathways of sorting and assembly of nuclear-encoded mitochondrial inner membrane proteins are described. In the first pathway, precursor proteins that carry amino-terminal targeting signals are initially translocated via contact sites ...
Hartl, Franz-Ulrich, Horwich, Arthur, Mahlke, Kerstin, Martin, Jörg, Neupert, Walter, Pfanner, Nikolaus   +5 more
core   +2 more sources

Processing of mitochondrial precursor proteins [PDF]

Biomedica biochimica acta, 1991
The mitochondrial processing enzyme consists of two components, the mitochondrial processing peptidase (MPP) and processing enhancing protein (PEP). MPP and PEP act cooperatively in proteolytic processing of mitochondrial precursor proteins. Most of the mitochondrial precursors possess aminoterminal presequences (also called "targeting sequences" or ...
Arretz, Michael, Neupert, Walter, Schneider, Helmut, Wienhues, Ulla   +3 more
core   +3 more sources

Contact sites between inner and outer membranes [PDF]

, 1990
Contact sites between both mitochondrial membranes play a predominant role in the transport of nuclear-coded precursor proteins into mitochondria. The characterization of contact sites was greatly advanced by the reversible accumulation of precursor ...
Attardi, Chen, Dumont, Eilers, Hackenbrock, Hartl, Hartl, Hartl, Hawlitschek, Hurt, Kellems, Nargang, Nicholson, Ostermann, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pon, Rassow, Rosenberg, Schleyer, Schwaiger, Stuart, Sztul, Söllner, Söllner, Vestweber   +30 more
core   +1 more source

Synthesis and assembly of mitochondrial proteins [PDF]

, 1988
Das, Rathindra C., Neupert, Walter, Nicholson, Donald W., Robbins, P. W.   +3 more
core   +4 more sources

Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding [PDF]

, 1994
Mdj1p, a novel member of the DnaJ family, is a heat shock protein that is associated with the inner membrane of mitochondria of Saccharomyces cerevisiae.
Amin, Arretz, Atencio, Bankier, Bardwell, Blumberg, Caplan, Caplan, Caplan, Cheng, Chirico, Church, Craig, Daum, Dear, Deshaies, Ellis, Feldheim, Gamer, Georgopoulos, Gibson, Glick, Hartl, Hill, Kang, Kobayashi, Krieg, Laemmli, Langer, Liberek, Luke, Manning-Krieg, Martin, Myers, Neupert, Neupert, Newman, Olson, Ostermann, Pearson, Pelham, Pfanner, Philippsen, Praekelt, Rassow, Riles, Rothblatt, Sadler, Sanger, Scherer, Schröder, Schwarz, Schwarz, Sherman, Sikorski, Silver, Smith, Southern, Stueber, Wickner, Young, Zhang, Zhong, Zylicz   +63 more
core   +1 more source