Results 11 to 20 of about 690,576 (265)

Evaluating the mitochondrial function [PDF]

open access: yesDiabetology & Metabolic Syndrome, 2012
We have read the article by Xia et.al. entitled as "L-carnitine ameliorated fatty liver in high-calorie diet/STZ induced type 2 diabetic mice by improving mitochondrial function" with great interest. In this article, the authors concluded that L-carnitine might be an effective liver cell protector for delaying the progression of type 2 diabetes ...
Akgul Emin   +2 more
doaj   +3 more sources

CFTR activity and mitochondrial function

open access: yesRedox Biology, 2013
Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
Angel Gabriel Valdivieso   +1 more
doaj   +4 more sources

Bioenergetic changes and mitochondrial dysfunction in mania versus euthymia in bipolar disorder type I

open access: yesEuropean Psychiatry, 2023
Introduction Current evidence has hypothesized the involvement of mitochondrial dysfunction during the acute episodes of BD compared to symptomatic remission.
A. Giménez-Palomo   +12 more
doaj   +1 more source

Comment on Yeste et al. Polyphenols and IUGR Pregnancies: Intrauterine Growth Restriction and Hydroxytyrosol Affect the Development and Neurotransmitter Profile of the Hippocampus in a Pig Model. Antioxidants 2021, 10, 1505

open access: yesAntioxidants, 2022
Intrauterine growth restriction (IUGR) affects 5–10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al.
Glòria Garrabou   +11 more
doaj   +1 more source

PINK1 in mitochondrial function [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
Rare, inherited mutations causing familial forms of Parkinson's disease (PD) have provided much insight into some of the molecular mechanisms that underlie both the genetic and sporadic forms of the disease. The role of mitochondria in sporadic PD has been debated for a little over 20 years, since the identification of complex I deficiency in the ...
Helene, Plun-Favreau, John, Hardy
openaire   +2 more sources

The Impact of Mitochondrial Deficiencies in Neuromuscular Diseases

open access: yesAntioxidants, 2020
Neuromuscular diseases (NMDs) are a heterogeneous group of acquired or inherited rare disorders caused by injury or dysfunction of the anterior horn cells of the spinal cord (lower motor neurons), peripheral nerves, neuromuscular junctions, or skeletal ...
Judith Cantó-Santos   +2 more
doaj   +1 more source

Mitochondrial Function in Sepsis [PDF]

open access: yesShock, 2016
Mitochondria are an essential part of the cellular infrastructure, being the primary site for high-energy adenosine triphosphate production through oxidative phosphorylation. Clearly, in severe systemic inflammatory states, like sepsis, cellular metabolism is usually altered, and end organ dysfunction is not only common, but also predictive of long ...
Nishkantha, Arulkumaran   +8 more
openaire   +2 more sources

Relevance of sex-differenced analyses in bioenergetics and nutritional studies

open access: yesFrontiers in Nutrition, 2022
Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males.
Glòria Garrabou   +7 more
doaj   +1 more source

Mitochondrial Functioning ≠ General Intelligence [PDF]

open access: yesJournal of Intelligence, 2020
Geary puts forward an appealing argument for the consideration of mitochondrial functioning as a candidate for a formative g Geary (2019); it is also an ambitious argument [...]
Alexander O. Savi   +3 more
openaire   +5 more sources

Unravelling inclusion body myositis using a patient‐derived fibroblast model

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology.
Judith Cantó‐Santos   +18 more
doaj   +1 more source

Home - About - Disclaimer - Privacy