Results 31 to 40 of about 690,576 (265)

#69 : Decline in Mitochondrial Function of Human Embryo with Maternal Aging

Fertility & Reproduction, 2023
Background and Aims: Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo.
Shu Hashimoto, Yoshiharu Morimoto
doaj   +1 more source

Mitochondrial Functions in Infection and Immunity [PDF]

Trends in Cell Biology, 2020
Mitochondria have a central role in regulating a range of cellular activities and host responses upon bacterial infection. Multiple pathogens affect mitochondria dynamics and functions to influence their intracellular survival or evade host immunity.
Tiku, Varnesh, Tan, Man-Wah, Đikić, Ivan   +2 more
openaire   +4 more sources

Mechanisms of Cell Damage and Protection in Ischemia/Reperfusion and Experimental Rationale for the Use of Lithium-Based Preparations in Anesthesiology

Общая реаниматология, 2013
Pharmaceuticals based on lithium ions have been already used in clinical practice for over 60 years for the treatment of bipolar disorders and remain a basic pharmacological therapy for patients with this disease.
V. V. Moroz, D. N. Silachev, E. Yu. Plotnikov, L. D. Zorova, I. B. Pevzner, O. A. Grebenchikov, V. V. Likhvantsev   +6 more
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Mitochondrial function of human embryo: Decline in their quality with maternal aging

Reproductive Medicine and Biology, 2022
Background Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo.
Shu Hashimoto, Yoshiharu Morimoto
doaj   +1 more source

Differential Metabolism of Medium-Chain Fatty Acids in Differentiated Human-Induced Pluripotent Stem Cell-Derived Astrocytes

Frontiers in Physiology, 2019
Medium-chain triglyceride (MCT) ketogenic diets increase ketone bodies, which are believed to act as alternative energy substrates in the injured brain. Octanoic (C8:0) and decanoic (C10:0) acids, which produce ketone bodies through β-oxidation, are used
Sarah Sonnay, Anirikh Chakrabarti, Jonathan Thevenet, Andreas Wiederkehr, Nicolas Christinat, Mojgan Masoodi, Mojgan Masoodi   +6 more
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Colonic Oxidative and Mitochondrial Function in Parkinson’s Disease and Idiopathic REM Sleep Behavior Disorder

Parkinson's Disease, 2017
Objective. To determine potential mitochondrial and oxidative alterations in colon biopsies from idiopathic REM sleep behavior disorder (iRBD) and Parkinson’s disease (PD) subjects. Methods.
C. Morén, Í. González-Casacuberta, J. Navarro-Otano, D. Juárez-Flores, D. Vilas, G. Garrabou, J. C. Milisenda, C. Pont-Sunyer, M. Catalán-García, M. Guitart-Mampel, E. Tobías, F. Cardellach, F. Valldeoriola, A. Iranzo, E. Tolosa   +14 more
doaj   +1 more source

Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2 G2019S -Parkinson’s disease

Journal of Translational Medicine, 2018
Background Mutations in leucine rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). Mitochondrial and autophagic dysfunction has been described as etiologic factors in different experimental models of PD. We aimed
Diana Luz Juárez-Flores, Ingrid González-Casacuberta, Mario Ezquerra, María Bañó, Francesc Carmona-Pontaque, Marc Catalán-García, Mariona Guitart-Mampel, Juan José Rivero, Ester Tobias, Jose Cesar Milisenda, Eduard Tolosa, Maria Jose Marti, Ruben Fernández-Santiago, Francesc Cardellach, Constanza Morén, Glòria Garrabou   +15 more
doaj   +1 more source

Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength

Nature Communications, 2022
Mitochondrial function is important for muscle maintenance and function, and mitochondrial proteolysis maintains mitochondrial integrity and function. Here the authors report that that loss of LONP1-dependent mitochondrial proteolysis in muscle causes ...
Zhisheng Xu, Tingting Fu, Qiqi Guo, Danxia Zhou, Wanping Sun, Zheng Zhou, Xinyi Chen, Jingzi Zhang, Lin Liu, Liwei Xiao, Yujing Yin, Yuhuan Jia, Erkai Pang, Yuncong Chen, Xin Pan, Lei Fang, Min-sheng Zhu, Wenyong Fei, Bin Lu, Zhenji Gan   +19 more
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Avocado Oil Prevents Kidney Injury and Normalizes Renal Vasodilation after Adrenergic Stimulation in Hypertensive Rats: Probable Role of Improvement in Mitochondrial Dysfunction and Oxidative Stress

Life, 2021
Hypertension impairs the function of the kidney and its vasculature. Adrenergic activation is involved in these processes by promoting oxidative stress and mitochondrial dysfunction.
Cristian Adrián Márquez-Ramírez, Berenice Eridani Olmos-Orizaba, Claudia Isabel García-Berumen, Elizabeth Calderón-Cortés, Rocío Montoya-Pérez, Alfredo Saavedra-Molina, Alain Raimundo Rodríguez-Orozco, Christian Cortés-Rojo   +7 more
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Telomeres and Mitochondrial Function [PDF]

Circulation Research, 2011
### Telomere Dysfunction Induces Metabolic and Mitochondrial Compromise Sahin et al Nature. 2011;470:359–365. A new study provides insight into aging and age-related diseases by linking telomere dysfunction to a decline in mitochondrial number and function.
openaire   +2 more sources