Results 31 to 40 of about 13,400,035 (354)
#69 : Decline in Mitochondrial Function of Human Embryo with Maternal Aging
Fertility & Reproduction, 2023 Background and Aims: Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo.
Shu Hashimoto, Yoshiharu Morimoto
doaj +1 more source
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. [PDF]
, 2011 To broadly explore mitochondrial structure and function as well as the communication of mitochondria with other cellular pathways, we constructed a quantitative, high-density genetic interaction map (the MITO-MAP) in Saccharomyces cerevisiae.
Cassidy-Stone, Ann +9 more
core +2 more sources
Mitochondrial function in sepsis [PDF]
European Journal of Clinical Investigation, 2013 AbstractBackgroundThe relevance of mitochondrial dysfunction as to pathogenesis of multiple organ dysfunction and failure in sepsis is controversial. This focused review evaluates the evidence for impaired mitochondrial function in sepsis.DesignReview of original studies in experimental sepsis animal models and clinical studies on mitochondrial ...
Jeger Victor +3 more
openaire +3 more sources
Antioxidants, 2020 Idiopathic Parkinson’s disease (iPD) and type 2 diabetes mellitus (T2DM) are chronic, multisystemic, and degenerative diseases associated with aging, with eventual epidemiological co-morbidity and overlap in molecular basis. This study aims to explore if
Diana Luz Juárez-Flores +22 more
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Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics
Redox Biology, 2020 Hydrogen sulfide (H2S) was once considered to have only toxic properties, until it was discovered to be an endogenous signaling molecule. The effects of H2S are dose dependent, with lower concentrations being beneficial and higher concentrations ...
B. Paul, S. Snyder, K. Kashfi
semanticscholar +1 more source
Disorders of mitochondrial function [PDF]
Current Opinion in Pediatrics, 2008 Mitochondrial diseases are a major category of childhood illness that produce a wide variety of symptoms and multisystemic disorders. This review highlights recent clinically important developments in diagnostic evaluation and treatment of mitochondrial diseases.Major advances have been made in understanding the genetic bases of mitochondrial diseases.
Debray, François-Guillaume +2 more
openaire +3 more sources
The essential role of mitochondrial dynamics in antiviral immunity. [PDF]
, 2018 Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun +3 more
core +2 more sources
Общая реаниматология, 2013 Pharmaceuticals based on lithium ions have been already used in clinical practice for over 60 years for the treatment of bipolar disorders and remain a basic pharmacological therapy for patients with this disease.
V. V. Moroz +6 more
doaj +1 more source
Mitochondrial function in immune cells in health and disease.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020 One of the main functions of mitochondria is production of ATP for cellular energy needs, however, it becomes more recognized that mitochondria are involved in differentiation and activation processes of immune cells. Upon activation, immune cells have a
M. Faas, P. Vos
semanticscholar +1 more source
A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. [PDF]
, 2018 BACKGROUND:Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood.
Aschbacher, Kirstin +7 more
core +1 more source