Results 71 to 80 of about 1,445,221 (211)

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome [PDF]

, 2009
Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-1 beta (IL-1 beta) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes triggered by microbial ligands, danger-associated molecular patterns
Mohamed Lamkanfi, James L. Mueller, Alberto C. Vitari, Shahram Misaghi, Anna Fedorova, Kurt Deshayes, Wyne P. Lee, Hal M. Hoffman, Vishva M. Dixit, Aguilar-Bryan, Ashcroft, Boyden, Cassel, Clement, Dostert, Duncan, Halle, Hamon, Hoffman, Hornung, Kanneganti, Kanneganti, Laliberte, Lamkanfi, Lamkanfi, Locovei, Ma, Mariathasan, Mariathasan, Martinon, Marty, Meyer, Miki, Miki, Pelegrin, Pelegrin, Perregaux, Riddle, Rosengren, Schott, Solle, Stoller, Sutterwala, Yvan-Charvet   +43 more
core   +2 more sources

The Three Pillars of ATP Production in Mammalian Sperm: Integrating Gluconeogenesis Into the Metabolic Framework

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose Mammalian sperm require a large amount of ATP to sustain motility. While glycolysis and oxidative phosphorylation (OXPHOS) are established ATP sources, they cannot fully explain motility maintenance under glucose‐deprived conditions.
Kosei Oishi, Reiji Tokito, Yasushi Yumura, Manabu Yoshida, Kaoru Yoshida, Masatsugu Asada, Koyuki Mikami, Hiroyuki Watanabe, Yuki Muranishi, Yasuyuki Kurihara   +9 more
wiley   +1 more source

Effect of Transcutaneous Acupoint Electrical Stimulation on Urinary Retention and Urinary ATP in Elderly Patients After Laparoscopic Cholecystectomy: A Prospective, Randomized, Controlled Clinical Trial

Clinical Interventions in Aging, 2022
Yanfang Zhang, Lirong Gong, Yuan Zhang, Shuan Dong, Jia Shi, Xiangyun Li, Yan Guo, Simeng He, Xiaoyang Wu, Shasha Liu, Huayang Liu, Lantian Zhang, Jianbo Yu Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical
Zhang Y, Gong L, Zhang Y, Dong S, Shi J, Li X, Guo Y, He S, Wu X, Liu S, Liu H, Zhang L, Yu J   +12 more
doaj  

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy

British Journal of Pharmacology, Volume 183, Issue 2, Page 296-312, January 2026.
Background and Purpose Neuroinflammation is increasingly recognised to contribute to drug‐resistant epilepsy. Activation of ATP‐gated P2X7 receptors has emerged as an important upstream mechanism, and increased P2X7 receptor expression is present in the seizure focus in rodent models and patients. Pharmacological antagonists of P2X7 receptors attenuate
Jaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H. M. Prehn, David C. Henshall, Tobias Engel   +6 more
wiley   +1 more source

BIOREMEDIATION OF CADMIUM CONTAMINATED WATER: BACTERIAL ACCUMULATION AND SURFACE COMPLEXITY BY REVIBACILLUS AGRI C15 AND BREVIBACILLUS AGRI C15 CDR [PDF]

مجلة الأنبار للعلوم الزراعية
Brevibacillus agri C15 and Brevibacillus agri C15 CdR have been reported as a tool for do uptake of cadmium (Cd). Nevertheless, it is unclear whether these strains contrast in their adsorption behaviors and surface complexation could be one of the ...
N. M. T. Jebril, A. K. Murad, R. Boden
doaj   +1 more source

Application of luciferase assay for ATP to antimicrobial drug susceptibility [PDF]

, 1977
The susceptibility of bacteria, particularly those derived from body fluids, to antimicrobial agents is determined in terms of an ATP index measured by culturing a bacterium in a growth medium.
Barza, M. J., Chappelle, E. W., Picciolo, G. L., Tuttle, S. A., Vellend, H., Weinstein, L.   +5 more
core   +1 more source

Ontogeny of purinergic receptor-regulated Ca2+ signaling in mouse cortical collecting duct epithelium [PDF]

, 2002
Changes in ATP-induced increase in {[}Ca2+], during collecting duct ontogeny were studied in primary monolayer cultures of mouse ureteric bud (UB) and cortical collecting duct (CCD) cells by Fura-PE3 fluorescence ratio imaging.
Borscheid, R., Braun, G. S., Horster, M. F., Huber, S. M., Tschop, J.   +4 more
core   +1 more source

Effects of CMV on T and NK Cells; With Emphasis on Immunometabolism

BioMed Research International, Volume 2026, Issue 1, 2026.
CMV is masterful at manipulating stress responses and conducting them in a way that yields beneficial outcomes. CMV always causes metabolic changes in the infected cells. However, nutritional status affects the pattern of events following CMV infection.
Haideh Namdari, Mohsen keshavarz, Maryam Hosseini, Farzad Parvizpour, Asrin Emami, Elahe Izadi, Milad Shahbazi Asl, Mehdi Shahgolzari, Farhad Rezaei, Baisakhi Banerjee   +9 more
wiley   +1 more source

The effectiveness of human SAGE medium compared to other conventional culture media on the ovine early embryonic development, in vitro [PDF]

Iraqi Journal of Veterinary Sciences
Developing an optimal in vitro embryo culture medium with high blastocyst rates and good-quality embryos remains challenging and controversial, as most culture media directly impact mammalian embryonic development.
Saif O. Al-Hafedh, Fatin Cedden, Ahmed O. Gatea   +2 more
doaj   +1 more source

Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]

, 2013
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Bhella, David, Hacker, Christian, Howell, Matthew, Lucocq, John   +3 more
core   +2 more sources