Results 81 to 90 of about 1,445,221 (211)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, Volume 599, Issue 23, Page 3524-3536, December 2025.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Fondová schémata jako možná řešení finanční udržitelnosti dánského penzijního systému

open access: yesTrendy v podnikání, 2020
The financial sustainability of pension systems is one of the crucial topics in the context of population aging. The issue of financial sustainability is primarily associated with public unfunded pension schemes, where there is an increase in future ...
Jan Pokorný, Pavlína Hejduková
doaj   +1 more source

Reagentless Real‐Time ATP Monitoring with New DNA Aptamers

open access: yesSmall, Volume 21, Issue 48, December 3, 2025.
A new aptamer is discovered via in vitro selection that binds to adenosine triphosphate (ATP) with high affinity (KD = 0.7 µm) and rejects closely related analogs including adenosine diphosphate (ADP), adenosine monophosphate (AMP), and adenosine. A fluorescent molecular beacon based on the aptamer enables continuous analyte monitoring in cell culture ...
Adara Bacon   +5 more
wiley   +1 more source

How did the world come into being? [PDF]

open access: yes, 2015
A fleeting and light-hearted Festschrift contribution on Leeds students' work collecting oral accounts of how the world came into ...
Hall, ATP
core   +2 more sources

Mitochondrial Dysfunction Contributes to Decompensation in a Zebrafish Model of Isoproterenol‐Induced Heart Failure

open access: yesActa Physiologica, Volume 241, Issue 12, December 2025.
ABSTRACT Aim Heart failure is a clinical syndrome where the heart's structural or functional impairment leads to inadequate blood flow to meet the body's metabolic demands. Mitochondrial dysfunction is increasingly recognized as a central contributor underlying the contractile impairment observed in the failing heart.
Manuel Vicente   +6 more
wiley   +1 more source

ATP-dependent chromatosome remodeling [PDF]

open access: yes, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Dimitrov S.   +6 more
core   +1 more source

Calcium binding to a remote site can replace magnesium as cofactor for mitochondrial Hsp90 (TRAP1) ATPase activity. [PDF]

open access: yes, 2018
The Hsp90 molecular chaperones are ATP-dependent enzymes that maintain protein homeostasis and regulate many essential cellular processes. Higher eukaryotes have organelle-specific Hsp90 paralogs that are adapted to each subcellular environment.
Agard, David A, Elnatan, Daniel
core  

Single molecule thermodynamics of ATP synthesis by F$_1$-ATPase

open access: yes, 2015
F$_\mathrm{o}$F$_1$-ATP synthase is a factory for synthesizing ATP in virtually all cells. Its core machinery is the subcomplex F$_1$-motor (F$_1$-ATPase) and performs the reversible mechanochemical coupling. Isolated F$_1$-motor hydrolyzes ATP, which is
Muneyuki, Eiro, Toyabe, Shoichi
core   +1 more source

Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs [PDF]

open access: yes, 1999
Background and Purpose-N-Methyl-D-aspartate (NMDA) elicits neuronally mediated cerebral arteriolar vasodilation that is reduced by ischemia/reperfusion (I/R).
David W. Busija   +4 more
core   +1 more source

Improved methods for counting bacteria in physiological fluids [PDF]

open access: yes, 1974
Bacterial population detection is based on detection of adenosine triphosphate (ATP), chemical present in all living matter. Amount of ATP in sample, after chemically removing all nonbacterial ATP, is directly related to bacterial population. Sensitivity
Picciolo, G. L.
core   +1 more source

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