Effects of CMV on T and NK Cells; With Emphasis on Immunometabolism
CMV is masterful at manipulating stress responses and conducting them in a way that yields beneficial outcomes. CMV always causes metabolic changes in the infected cells. However, nutritional status affects the pattern of events following CMV infection.
Haideh Namdari +9 more
wiley +1 more source
Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]
ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Schuurman-Wolters, Gea, +14 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
ATP-induced changes in intracellular calcium and extracellular H+ flux.
(A) 1 μM ATP increased intracellular calcium as reported by changes in the fluorescence of the calcium indicator Oregon Green. Subsequent ATP-induced alterations in Oregon Green fluorescence were blocked by 1 μM thapsigargin applied for 15 minutes. (B) A
Robert Paul Malchow (4872022) +10 more
core +1 more source
Reagentless Real‐Time ATP Monitoring with New DNA Aptamers
A new aptamer is discovered via in vitro selection that binds to adenosine triphosphate (ATP) with high affinity (KD = 0.7 µm) and rejects closely related analogs including adenosine diphosphate (ADP), adenosine monophosphate (AMP), and adenosine. A fluorescent molecular beacon based on the aptamer enables continuous analyte monitoring in cell culture ...
Adara Bacon +5 more
wiley +1 more source
Die Infrarotspektroskopie in Verbindung mit photoaktivierbaren Substraten wurde zur Untersuchung von Substrat-Protein-Wechselwirkungen eingesetzt. Dabei wurden Konformationsänderungen der Ca2+-ATPase des Sarkoplasmatischen Retikulums bei Bindung des ...
Liu, Man
core
Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M +43 more
core +1 more source
Mechanistic insights into ATP hydrolysis by the ABC transporter TAP
The transporter associated with antigen processing (TAP) plays a pivotal role in the adaptive immune response against virus-infected or malignantly transformed cells.
Chen, Min
core
Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Spyer, K. Michael +7 more
core +1 more source
En el presente documento, se presenta un algoritmo que permite distinguir de forma clara y precisa, las faltas transitorias de las permanentes. Adicionalmente se determina el instante de extinción del arco secundario, para así evitar o controlar de forma
Miguel Martínez
doaj

