Results 11 to 20 of about 365,133 (265)
Journal of Alzheimer's Disease, 2010 Caffeine causes most of its biological effects via antagonizing all types of adenosine receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons and glial cells of all brain areas. In consequence, caffeine, when acting as an AR antagonist, is doing the opposite of activation of adenosine receptors due to removal of ...
Ribeiro, Joaquim A., Sebastião, Ana M
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Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug? [PDF]
The Journal of Pharmacology and Experimental Therapeutics, 2019 Adenosine receptors (ARs) represent key drug targets in many human pathologies, including cardiovascular, neurologic, and inflammatory diseases. To overcome the very rapid metabolization of adenosine, metabolically stable AR agonists and antagonists were developed.
Rouquette, Marie +9 more
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Computerized Modeling of Adenosine Triphosphate, Adenosine Triarsenate and Adenosine Trivanadate [PDF]
Molecules, 2012 Computerized molecular models of adenosine triphosphate, adenosine tri-arsenate and adenosine trivanadate have been generated using the molecular mechanics technique. The analysis of structural parameters indicated that, at least theoretically, adenosine triarsenate is a realistic candidate for replacement of adenosine triphosphate in biochemical ...
Nascimento, Valter A. +2 more
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Extracellular adenosine triphosphate and adenosine in cancer [PDF]
Oncogene, 2010 Adenosine triphosphate (ATP) is actively released in the extracellular environment in response to tissue damage and cellular stress. Through the activation of P2X and P2Y receptors, extracellular ATP enhances tissue repair, promotes the recruitment of immune phagocytes and dendritic cells, and acts as a co-activator of NLR family, pyrin domain ...
Stagg, J., Smyth, M. J.
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Adenosine washing improves the retention rate of fat grafts under conditions of obesity [PDF]
Archives of Aesthetic Plastic SurgeryBackground Fat grafting is a commonly employed aesthetic procedure for contour enhancement. However, outcome prediction is challenging due to the complex regeneration and remodeling processes involved.
Beom Jun Kim +3 more
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Adenosinergic System Involvement in Ischemic Stroke Patients’ Lymphocytes
Cells, 2020 Adenosine modulates many physiological processes through the interaction with adenosine receptors (ARs) named as A1, A2A, A2B, and A3ARs. During ischemic stroke, adenosine mediates neuroprotective and anti-inflammatory effects through ARs activation. One
Silvia Pasquini +7 more
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Frontiers in Bioscience-Elite, 2022 Basidiomycetes-X, of which Japanese vernacular name is Echigoshirayukidake, is a local speciality mushroom found and cultivated in Japan that has been distributed as a precious cuisine material or as a functional food with medicinal properties ...
Toshio Sakamoto +9 more
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Nanomaterials, 2021 Carbon nanotube field effect transistor (CNT FET) aptasensors have been investigated for the detection of adenosine using two different aptamer sequences, a 35-mer and a 27-mer.
Hong Phan T. Nguyen +2 more
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The Effect of Low-Doses of Caffeine and Taurine on Convulsive Seizure Parameters in Rats
Behavioral Sciences, 2020 Introduction: Caffeine, an adenosine-receptor blocker, is believed to have neuronal excitatory effects, while Taurine, a mammalian amino acid, was shown to have neuroinhibitory effects.
Mohamed Jailani +9 more
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Frontiers in Pharmacology, 2017 Adenosine is an ancient extracellular signaling molecule that regulates various biological functions via activating four G-protein-coupled receptors, A1, A2A, A2B, and A3 adenosine receptors. As such, several studies have highlighted a role for adenosine signaling in affecting the T cell development in the thymus. Recent studies indicate that adenosine
Krisztina Köröskényi +5 more
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