Results 71 to 80 of about 22,572 (176)

Circadian Clock: A Regulator of Immunity in Autoimmune Diseases

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
This review explores the intricate connections between circadian clocks and immune responses in autoimmune diseases. We aim to open new avenues for therapeutic interventions, including chronotherapy and targeting clock genes, with the potential to improve treatment outcomes in autoimmune diseases.
Ye‐Jun Wu, Shu‐Ying Zhang, Hong‐Yu Chen, Xin‐Ran He, Guang‐Rui Yang   +4 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, Volume 3, Issue 5, September 2025.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Optical redox imaging of ANT1-deficient muscles

Journal of Innovative Optical Health Sciences
Adenine nucleotide translocator (ANT) is a mitochondrial protein involved in the exchange of ADP and ATP across the mitochondrial inner membrane. It plays a crucial role in cellular energy metabolism by facilitating the transport of ATP synthesized ...
He N. Xu, Ryan M. Morrow, Min Feng, Huaqing Zhao, Douglas Wallace, Lin Z. Li   +5 more
doaj   +1 more source

COMPARATIVE STUDY OF SIGNIFICANCE OF NON-INVASIVE DIAGNOSTIC METHODS IN INFLAMMATORY DISEASES OF THE HEART

Российский кардиологический журнал, 2018
Aim. To evaluate diagnostic significance of non-invasive methods of myocarditis diagnostics.Material  and  methods. To the study, 141 patient included with suspected myocarditis (104 males, 37 females; age 11-69, mean age 42,7±13,7 y. o.).
V. A. Titov, E. S. Ignatieva, L. B. Mitrofanova, D. V. Ryzhkova, D. A. Zverev, D. S. Lebedev, О. M. Moiseeva   +6 more
doaj   +1 more source

Emerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.
Anwar Ali, Quratulain Babar, Ayesha Saeed, Domenico Sergi, Nenad Naumovski, Isam A. Mohamed Ahmed, Ghalia Shamlan, Halah Abdulrahman Hafiz, Muhammad Faisal Manzoor, Joanna Trafialek, Felix Kwashie Madilo   +10 more
wiley   +1 more source

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source

Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases

Pharmaceuticals, 2010
Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are the most common human adult-onset neurodegenerative diseases.
Lee J. Martin
doaj   +1 more source

The mitochondrial permeability transition, F-ATP synthase and the adenine nucleotide translocator: Where do we stand?

Biochimica et Biophysica Acta, 2022
P. Bernardi, Michela Carraro, G. Lippe
semanticscholar   +1 more source

Assessing the relative role of F-ATP synthase and adenine nucleotide translocator in the permeability transition

Biochimica et Biophysica Acta, 2022
Ludovica Tommasin, Michela Carraro, P. Bernardi   +2 more
semanticscholar   +1 more source

Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (FRG1) expression during human myogenic differentiation

BMC Biology, 2009
Background Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder associated with the partial deletion of integral numbers of 3.3 kb D4Z4 DNA repeats within the subtelomere of chromosome 4q.
Marozzi Anna, Meneveri Raffaella, Mora Marina, Brunelli Silvia, Cheli Stefania, Grasser Florian, Ramirez Gabriella, Bodega Beatrice, Mueller Stefan, Battaglioli Elena, Ginelli Enrico   +10 more
doaj   +1 more source