Results 101 to 110 of about 114,992 (358)

Metal‐free phthalimide‐labeled peptide nucleic acids for electrochemical biosensing applications

Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Peptide nucleic acids (PNAs) are neutral mimics of natural DNA and RNA biopolymers that have caught the attention of researchers working on the identification of specific sequences of nucleobases in DNA/RNA strands. For this purpose, specific analytical protocols need to be developed to optimize the nucleic acid recognition ability of PNAs ...
Mirko Magni, Sergio Dall'Angelo, Clara Baldoli, Emanuela Licandro, Luigi Falciola, Patrizia R. Mussini   +5 more
wiley   +1 more source

Production of riboflavin and related cofactors by biotechnological processes

Microbial Cell Factories, 2020
Riboflavin (RF) and its active forms, the cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), have been extensively used in the food, feed and pharmaceutical industries.
Shuang Liu, Wenya Hu, Zhiwen Wang, Tao Chen   +3 more
doaj   +1 more source

Recent advances in experimental techniques to probe fast excited-state dynamics in biological molecules in the gas phase : dynamics in nucleotides, amino acids and beyond [PDF]

, 2013
In many chemical reactions, an activation barrier must be overcome before a chemical transformation can occur. As such, understanding the behaviour of molecules in energetically excited states is critical to understanding the chemical changes that these ...
Hadden DJ, Lodish H, Rossle S, Satzger H, Scoles G, Vastola FJ, Yang X   +6 more
core   +1 more source

Interaction of Oligonucleotides with Gold Nanoparticles: Factors Beyond Electrostatic and Van‐Der Waals Forces

Advanced Materials Interfaces, EarlyView.
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur, Nicola Cavallini, Debora Ferrari, Laura Fabris   +3 more
wiley   +1 more source

Non‐traditional encryption methods: Moving toward electrochemical cryptography

Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Cybersecurity and encryption are critical in diverse applications from simple emails to high‐priority government secrets. It is best accomplished by an “unbreakable” cipher or one which is only decrypted by those with a matching cipher key to the initial encryption.
Giana Biddle, Leif McGoldrick, Jan Halamek   +2 more
wiley   +1 more source

A DNP‐Supported Solid‐State NMR Approach to Study Nucleic Acids In Situ Reveals Berberine‐Stabilized Hoogsteen Structures in Mitochondria

Angewandte Chemie, EarlyView.
Mitochondria are vital for energy production and rely on intricate nucleic acid structures to regulate gene expression. Using DNP‐ssNMR (dynamic nuclear polarization solid‐state NMR), we observed G‐quadruplex formation in intact mitochondria treated with berberine.
Michaela Dzurov Krafčíková, David Beriashvili, Salima Bahri, Menno Bergmeijer, Stuart C. Howes, Andrei Gurinov, Friedrich G. Förster, Gert E. Folkers, Marc Baldus   +8 more
wiley   +2 more sources

Identification, Heterologous Expression, and Functional Characterization of Bacillus subtilis YutF, a HAD Superfamily 5'-Nucleotidase with Broad Substrate Specificity. [PDF]

PLoS ONE, 2016
5'-nucleotidases (EC 3.1.3.5) catalyze the hydrolytic dephosphorylation of 5'-ribonucleotides and 5'-deoxyribonucleotides as well as complex nucleotides, such as uridine 5'-diphosphoglucose (UDP-glucose), nicotinamide adenine dinucleotide and flavin ...
Natalia P Zakataeva, Dmitriy V Romanenkov, Yuliya R Yusupova, Victoria S Skripnikova, Takayuki Asahara, Sergey V Gronskiy   +5 more
doaj   +1 more source

Influence of the environment and probes on rapid DNA sequencing via transverse electronic transport [PDF]

, 2007
We study theoretically the feasibility of using transverse electronic transport within a nanopore for rapid DNA sequencing. Specifically, we examine the effects of the environment and detection probes on the distinguishability of the DNA bases.
Akeson, Aksimentiev, Biance, Braslavsky, Chen, Collins, Deamer, Deamer, Di Ventra, Fologea, Fologea, Foloppe, Gracheva, Grun, Harrell, Heng, Ji, Johan Lagerqvist, Jorgensen, Kale, Kasianowicz, Lagerqvist, Lander, Lemay, Li, Li, Li, Lin, MacKerell, Mannion, Massimiliano Di Ventra, Mathé, Meller, Meller, Meller, Michael Zwolak, Nakane, Rabin, Rappe, Sauer-Budge, Storm, Venter, Vercoutere, Yang, Zwolak   +44 more
core   +3 more sources

Statistical distributions of sequencing by synthesis with probabilistic nucleotide incorporation [PDF]

Journal of Computational Biology. June 2009, 16(6): 817-827, 2014
Sequencing by synthesis is used in many next-generation DNA sequencing technologies. Some of the technologies, especially those exploring the principle of single-molecule sequencing, allow incomplete nucleotide incorporation in each cycle. We derive statistical distributions for sequencing by synthesis by taking into account the possibility that ...
arxiv   +1 more source

PNA Functionalized Gold Nanoparticles on TiO2 Nanotubes Biosensor for Electrochemical DNA Fragment Detection

Advanced Materials Interfaces, EarlyView.
This experiment investigates the development of a highly sensitive biosensor platform incorporating AuNPs with TiO2‐NTs as electrode materials. Robust PNA probes and an optimized hybridization protocol are employed to enhance performance. An appropriate level of AuNPs on the surface effectively prevents non‐specific binding of target DNA fragments ...
Younghwan Kim, Swomitra Kumar Mohanty
wiley   +1 more source